Resveratrol as a novel treatment for diseases with mTOR pathway hyperactivation (Q38552040)

4 September 2017

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title

Resveratrol as a novel treatment for diseases with mTOR pathway hyperactivation (English)

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4 September 2017

Anya Alayev

1

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4 September 2017

Sara Malka Berger

series ordinal

2

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4 September 2017

Marina K Holz

series ordinal

3

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4 September 2017

language of work or name

English

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publication date

22 July 2015

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Annals of the New York Academy of Sciences

4 September 2017

published in

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4 September 2017

volume

1348

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4 September 2017

issue

1

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4 September 2017

page(s)

116-123

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Wine, alcohol, platelets, and the French paradox for coronary heart disease

4 September 2017

cites work

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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

21 January 2018

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Resveratrol analog, 3,4,5,4'-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts

21 January 2018

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Resveratrol analogs: promising chemopreventive agents

21 January 2018

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Biosynthesis of methylated resveratrol analogs through the construction of an artificial biosynthetic pathway in E. coli.

21 January 2018

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Pterostilbene, an Active Constituent of Blueberries, Stimulates Nitric Oxide Production via Activation of Endothelial Nitric Oxide Synthase in Human Umbilical Vein Endothelial Cells.

21 January 2018

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Anti-tumor properties of cis-resveratrol methylated analogs in metastatic mouse melanoma cells

21 January 2018

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Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

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Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses

21 January 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

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Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

21 January 2018

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Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol

21 January 2018

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Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells.

21 January 2018

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Resveratrol as a therapeutic agent for neurodegenerative diseases

21 January 2018

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Resveratrol and life extension.

21 January 2018

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Resveratrol, obesity and diabetes.

21 January 2018

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Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis

21 January 2018

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Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1

21 January 2018

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mTOR signaling for biological control and cancer

21 January 2018

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Identification and characterization of a mitogen-activated S6 kinase

21 January 2018

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Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

21 January 2018

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Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

21 January 2018

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

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Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

21 January 2018

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Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy

21 January 2018

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Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling

21 January 2018

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

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Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells

21 January 2018

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DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

21 January 2018

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Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR

21 January 2018

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Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

21 January 2018

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Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation

21 January 2018

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

21 January 2018

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

21 January 2018

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Resveratrol is not a direct activator of SIRT1 enzyme activity

21 January 2018

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SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

21 January 2018

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SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase

21 January 2018

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Breast cancer incidence rates in U.S. women are no longer declining

21 January 2018

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Breast cancer statistics, 2011

21 January 2018

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Phytoestrogen exposure elevates PTEN levels

21 January 2018

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Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice

21 January 2018

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Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.

21 January 2018

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Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo

21 January 2018

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Effect of resveratrol on growth of 4T1 breast cancer cells in vitro and in vivo

21 January 2018

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SIRT1 negatively regulates the mammalian target of rapamycin

21 January 2018

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Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway

21 January 2018

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Monitoring autophagic degradation of p62/SQSTM1.

21 January 2018

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Role and regulation of autophagy in cancer

21 January 2018

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The double-edged sword of autophagy modulation in cancer

21 January 2018

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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Anti- and pro-tumor functions of autophagy

21 January 2018

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

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Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

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A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

21 January 2018

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

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Autophagy takes flight in Drosophila

21 January 2018

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Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy

21 January 2018

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Life and death partners: apoptosis, autophagy and the cross-talk between them

21 January 2018

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Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

21 January 2018

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mTOR: more targets of resveratrol?

21 January 2018

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Resveratrol and cancer: focus on in vivo evidence

21 January 2018

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Human, rat, and mouse metabolism of resveratrol.

21 January 2018

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Absorption of trans-resveratrol in rats

21 January 2018

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Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts

21 January 2018

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Lymphangioleiomyomatosis - a wolf in sheep's clothing.

21 January 2018

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Frequent estrogen and progesterone receptor immunoreactivity in renal angiomyolipomas from women with pulmonary lymphangioleiomyomatosis

21 January 2018

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Lymphangioleiomyomatosis: a clinical update.

21 January 2018

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Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

21 January 2018

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Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells

21 January 2018

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Overcoming endocrine therapy resistance by signal transduction inhibition

21 January 2018

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Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

21 January 2018

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The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells

21 January 2018

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Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling

21 January 2018

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Effects of combining rapamycin and resveratrol on apoptosis and growth of TSC2-deficient xenograft tumors

21 January 2018

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One-Year Consumption of a Grape Nutraceutical Containing Resveratrol Improves the Inflammatory and Fibrinolytic Status of Patients in Primary Prevention of Cardiovascular Disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/NYAS.12829

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4 September 2017

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