Mechanisms of Invasion in Head and Neck Cancer (Q38517084)

3 September 2017

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title

Mechanisms of Invasion in Head and Neck Cancer (English)

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3 September 2017

Lizandra Jimenez

1

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3 September 2017

Sangeeta K Jayakar

series ordinal

2

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3 September 2017

Thomas J Ow

series ordinal

3

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3 September 2017

Jeffrey E Segall

series ordinal

4

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3 September 2017

publication date

5 June 2015

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Archives of Pathology & Laboratory Medicine

3 September 2017

published in

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3 September 2017

volume

139

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3 September 2017

issue

11

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3 September 2017

page(s)

1334-1348

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Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma

3 September 2017

cites work

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12 December 2020

Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway

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12 December 2020

Icotinib inhibits the invasion of Tca8113 cells via downregulation of nuclear factor κB-mediated matrix metalloproteinase expression

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12 December 2020

Soluble fibronectin promotes migration of oral squamous-cell carcinoma cells

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12 December 2020

Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma

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12 December 2020

Slug is a key mediator of hypoxia induced cadherin switch in HNSCC: correlations with poor prognosis.

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12 December 2020

Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation

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12 December 2020

Biological significance of c-erbB family oncogenes in head and neck cancer

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12 December 2020

Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion

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12 December 2020

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

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12 December 2020

Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions.

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12 December 2020

Significance of dysregulated metadherin and microRNA-375 in head and neck cancer.

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12 December 2020

Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A

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12 December 2020

Selaginellatamariscina attenuates metastasis via Akt pathways in oral cancer cells

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12 December 2020

Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β.

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12 December 2020

The epithelial-mesenchymal transition generates cells with properties of stem cells

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12 December 2020

miR-639 regulates transforming growth factor beta-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting FOXC1.

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12 December 2020

DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis

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12 December 2020

Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.

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12 December 2020

The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma

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12 December 2020

Reciprocal effects between microRNA-140-5p and ADAM10 suppress migration and invasion of human tongue cancer cells

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12 December 2020

Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity

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12 December 2020

The impact of perineural invasion and/or lymphovascular invasion on the survival of early-stage oral squamous cell carcinoma patients.

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12 December 2020

Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma

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12 December 2020

TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

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12 December 2020

Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma

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12 December 2020

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.

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12 December 2020

Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells

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12 December 2020

Epidermal growth factor receptor biology in head and neck cancer

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12 December 2020

Low-Level Expression of miR-375 Correlates with Poor Outcome and Metastasis While Altering the Invasive Properties of Head and Neck Squamous Cell Carcinomas

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12 December 2020

Development of a quantitative method to analyse tumour cell invasion in organotypic culture

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12 December 2020

Collagen XVI in health and disease

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12 December 2020

Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma

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12 December 2020

Histological pattern of mandibular invasion by oral squamous cell carcinoma

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12 December 2020

Protection of dietary polyphenols against oral cancer

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12 December 2020

MicroRNA-21 promotes oral cancer invasion via the Wnt/β-catenin pathway by targeting DKK2.

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12 December 2020

Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

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12 December 2020

Uncoupling of epidermal growth factor-dependent proliferation and invasion in a model of squamous carcinoma progression.

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12 December 2020

Digging a little deeper: the stages of invadopodium formation and maturation

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12 December 2020

Hallmarks of Cancer: The Next Generation

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12 December 2020

The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent mechanism

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12 December 2020

Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC).

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12 December 2020

Matrix metalloproteinases and TGFbeta1 modulate oral tumor cell matrix

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12 December 2020

Irradiated fibroblast-induced bystander effects on invasive growth of squamous cell carcinoma under cancer-stromal cell interaction

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12 December 2020

EMMPRIN modulates migration and deposition of TN-C in oral squamous carcinoma

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12 December 2020

Regulation of HGF and SDF-1 expression by oral fibroblasts--implications for invasion of oral cancer

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12 December 2020

microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase Cɛ

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12 December 2020

Endothelial cells expressing Bcl-2 promotes tumor metastasis by enhancing tumor angiogenesis, blood vessel leakiness and tumor invasion

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12 December 2020

Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion.

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12 December 2020

Cigarette smoke condensate promotes pro-tumourigenic stromal-epithelial interactions by suppressing miR-145.

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12 December 2020

CXCR4 Promotes Oral Squamous Cell Carcinoma Migration and Invasion through Inducing Expression of MMP-9 and MMP-13 via the ERK Signaling Pathway

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12 December 2020

Effects of activated fibroblasts on phenotype modulation, EGFR signalling and cell cycle regulation in OSCC cells.

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12 December 2020

Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway

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12 December 2020

Glial cell line-derived neurotrophic factor induces cell migration in human oral squamous cell carcinoma

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12 December 2020

Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways

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12 December 2020

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

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12 December 2020

Validation of the risk model: high-risk classification and tumor pattern of invasion predict outcome for patients with low-stage oral cavity squamous cell carcinoma.

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12 December 2020

Stromal transforming growth factor-beta 1 is crucial for reinforcing the invasive potential of low invasive cancer.

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12 December 2020

Black Tea Polyphenols Reverse Epithelial-to-Mesenchymal Transition and Suppress Cancer Invasion and Proteases in Human Oral Cancer Cells

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12 December 2020

Kinetics of Epidermal Growth Factor in Saliva

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12 December 2020

MicroRNA-29a upregulates MMP2 in oral squamous cell carcinoma to promote cancer invasion and anti-apoptosis

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12 December 2020

Heparanase is involved in the proliferation and invasion of nasopharyngeal carcinoma cells

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12 December 2020

Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype

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12 December 2020

Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN oral squamous cell carcinoma with extranodal spread.

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12 December 2020

Integrin αβ1, αvβ, α6β effectors p130Cas, Src and talin regulate carcinoma invasion and chemoresistance

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12 December 2020

The paracrine effect of cancer-associated fibroblast-induced interleukin-33 regulates the invasiveness of head and neck squamous cell carcinoma

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12 December 2020

Grape Seed Proanthocyanidins Inhibit the Invasiveness of Human HNSCC Cells by Targeting EGFR and Reversing the Epithelial-To-Mesenchymal Transition

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12 December 2020

Regulation of invadopodia by the tumor microenvironment

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12 December 2020

Akt/Ezrin Tyr353/NF-κB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma

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12 December 2020

Tumor cell invasion and survival in head and neck cancer

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12 December 2020

Prognostic value of transforming growth factor beta 1 [TGF-β1] and matrix metalloproteinase 9 [MMP-9] in oral squamous cell carcinoma

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12 December 2020

Matrix metalloproteinases and tumor metastasis

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12 December 2020

HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer

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12 December 2020

Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression

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12 December 2020

Blocking the Na /H exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma

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12 December 2020

Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma

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12 December 2020

Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells

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12 December 2020

Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative

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12 December 2020

Epithelial to mesenchymal transition in head and neck squamous cell carcinoma

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12 December 2020

SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells

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12 December 2020

STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell carcinoma growth in vitro and in vivo

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12 December 2020

Inhibition of TGF-beta1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases

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12 December 2020

Dysregulated miR-363 affects head and neck cancer invasion and metastasis by targeting podoplanin

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12 December 2020

Adhesion rings surround invadopodia and promote maturation

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12 December 2020

Heparin-binding epidermal growth factor-like growth factor is a potent regulator of invasion activity in oral squamous cell carcinoma

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12 December 2020

Physiologic levels of epidermal growth factor in saliva stimulate cell migration of an oral epithelial cell line, HO-1-N-1.

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12 December 2020

The chemokine receptors CXCR1 and CXCR2 regulate oral cancer cell behaviour.

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12 December 2020

The epidermal growth factor receptor ligands at a glance

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12 December 2020

Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis

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12 December 2020

Grape seed proanthocyanidins inhibit the invasive potential of head and neck cutaneous squamous cell carcinoma cells by targeting EGFR expression and epithelial-to-mesenchymal transition

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12 December 2020

Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

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12 December 2020

The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma

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12 December 2020

Antimetastatic effects of licochalcone A on oral cancer via regulating metastasis-associated proteases

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12 December 2020

CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma

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12 December 2020

ECM degradation assays for analyzing local cell invasion

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12 December 2020

Persistent activation of Rac1 in squamous carcinomas of the head and neck: evidence for an EGFR/Vav2 signaling axis involved in cell invasion.

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12 December 2020

Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma

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12 December 2020

Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

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12 December 2020

Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas

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12 December 2020

Membrane Type 1 Matrix Metalloproteinase induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells

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12 December 2020

Suppressive effect of microRNA-126 on oral squamous cell carcinoma in vitro

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12 December 2020

The parotid gland is the main source of human salivary epidermal growth factor

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12 December 2020

Three-dimensional reconstruction of oral tongue squamous cell carcinoma at invasion front

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12 December 2020

Role of stromal thrombospondin-1 in motility and proteolytic activity of oral squamous cell carcinoma cells.

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12 December 2020

A novel high-throughput screening system identifies a small molecule repressive for matrix metalloproteinase-9 expression

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12 December 2020

Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.

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12 December 2020

Histological and molecular aspects of oral squamous cell carcinoma (Review)

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12 December 2020

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

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12 December 2020

Inhibitors of NF-kappaB reverse cellular invasion and target gene upregulation in an experimental model of aggressive oral squamous cell carcinoma

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12 December 2020

The chemokine receptor-CXCR2 plays a critical role in the invasion and metastases of oral squamous cell carcinoma in vitro and in vivo

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12 December 2020

miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis

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12 December 2020

ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness

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12 December 2020

Directed cell invasion and migration during metastasis

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12 December 2020

Down regulation of RhoC by microRNA-138 results in de-activation of FAK, Src and Erk1/2 signaling pathway in head and neck squamous cell carcinoma

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12 December 2020

Comparative analysis of basal lamina type IV collagen α chains, matrix metalloproteinases-2 and -9 expressions in oral dysplasia and invasive carcinoma

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12 December 2020

The molecular biology of head and neck cancer

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12 December 2020

Classifying collective cancer cell invasion

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12 December 2020

Invadopodia formation in oral squamous cell carcinoma: the role of epidermal growth factor receptor signalling

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12 December 2020

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation

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12 December 2020

Markers of epithelial to mesenchymal transition in association with survival in head and neck squamous cell carcinoma (HNSCC).

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12 December 2020

Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma

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12 December 2020

Stat3 is involved in the motility, metastasis and prognosis in lingual squamous cell carcinoma.

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12 December 2020

Effects of epidermal growth factor on the invasive activity and cytoskeleton of oral squamous cell carcinoma cell lines

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12 December 2020

MicroRNAs in human cancer

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12 December 2020

Type IV collagenases in tumor invasion and metastasis

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12 December 2020

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma

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12 December 2020

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma

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12 December 2020

Invadopodia: specialized cell structures for cancer invasion

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12 December 2020

Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma.

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12 December 2020

Perivascular stem cell niche in head and neck cancer

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12 December 2020

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

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12 December 2020

Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells.

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12 December 2020

Transforming growth factor-β1 treatment of oral cancer induces epithelial-mesenchymal transition and promotes bone invasion via enhanced activity of osteoclasts

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12 December 2020

Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression.

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12 December 2020

Oral squamous cell carcinoma invasion is associated with a laminin-5 matrix re-organization but independent of basement membrane and hemidesmosome formation. clues from an in vitro invasion model.

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12 December 2020

Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2, and IL-6.

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12 December 2020

The tumor microenvironment contribution to development, growth, invasion and metastasis of head and neck squamous cell carcinomas

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12 December 2020

Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma

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12 December 2020

DNA copy number variation and loss of heterozygosity in relation to recurrence of and survival from head and neck squamous cell carcinoma: a review

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12 December 2020

microRNAs are important players in head and neck carcinoma: a review

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12 December 2020

SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway

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12 December 2020

MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1.

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12 December 2020

Validation of the histologic risk model in a new cohort of patients with head and neck squamous cell carcinoma.

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12 December 2020

p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway

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12 December 2020

Role of interleukin-8 secreted from human oral squamous cell carcinoma cell lines

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12 December 2020

Functional relevance of urinary-type plasminogen activator receptor-alpha3beta1 integrin association in proteinase regulatory pathways

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12 December 2020

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12 December 2020

AKT primes snail-induced EMT concomitantly with the collective migration of squamous cell carcinoma cells

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12 December 2020

Notch signaling induces EMT in OSCC cell lines in a hypoxic environment

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12 December 2020

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12 December 2020

Induction of type XVI collagen expression facilitates proliferation of oral cancer cells

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12 December 2020

Alphavbeta6 integrin in wound healing and cancer of the oral cavity

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12 December 2020

Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma

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12 December 2020

A study of an in vitro model for invasion of oral squamous cell carcinoma

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12 December 2020

Decreased plakophilin-1 expression promotes increased motility in head and neck squamous cell carcinoma cells

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12 December 2020

Src-homology 2 domain-containing tyrosine phosphatase 2 promotes oral cancer invasion and metastasis

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12 December 2020

Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth

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12 December 2020

Signaling inputs to invadopodia and podosomes

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12 December 2020

EGF receptor activation by GPCRs: an universal pathway reveals different versions

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12 December 2020

HIF-2alpha-mediated activation of the epidermal growth factor receptor potentiates head and neck cancer cell migration in response to hypoxia

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12 December 2020

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

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12 December 2020

Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells

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12 December 2020

The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas

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12 December 2020

Small interfering RNA targeting ILK inhibits metastasis in human tongue cancer cells through repression of epithelial-to-mesenchymal transition

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12 December 2020

Role of insulin-like growth factor-II mRNA-binding protein-3 in invadopodia formation and the growth of oral squamous cell carcinoma in athymic nude mice

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12 December 2020

Epidermal growth factor EGF in human saliva: effect of age, sex, race, pregnancy and sialogogue

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12 December 2020

The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion

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12 December 2020

Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion.

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12 December 2020

miR-29b suppresses proliferation, migration, and invasion of tongue squamous cell carcinoma through PTEN-AKT signaling pathway by targeting Sp1.

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12 December 2020

Clinicobiological progression and prognosis of oral squamous cell carcinoma in relation to the tumor invasive front: impact on prognosis.

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12 December 2020

A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma

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12 December 2020

Docetaxel suppresses invasiveness of head and neck cancer cells in vitro

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12 December 2020

Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells

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12 December 2020

Cross-talk between estrogen receptor and epidermal growth factor receptor in head and neck squamous cell carcinoma

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12 December 2020

Autocrine and paracrine motility factors and their involvement in invasiveness in a human oral carcinoma cell line

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12 December 2020

Matrix Metalloproteinases and Their Inhibitors: Correlation with Invasion and Metastasis in Oral Cancer

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12 December 2020

Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma

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12 December 2020

Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor.

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12 December 2020

Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.

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12 December 2020

Inhibition of epidermal growth factor-induced invasion by dexamethasone and AP-1 decoy in human squamous cell carcinoma cell lines

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12 December 2020

Concomitant loss of p120-catenin and β-catenin membrane expression and oral carcinoma progression with E-cadherin reduction

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12 December 2020

MicroRNAs function as tumor suppressors or oncogenes: aberrant expression of microRNAs in head and neck squamous cell carcinoma

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12 December 2020

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

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12 December 2020

Spatiotemporal regulation of Src and its substrates at invadosomes

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12 December 2020

Targeting Galectin-1 in Carcinoma-Associated Fibroblasts Inhibits Oral Squamous Cell Carcinoma Metastasis by Downregulating MCP-1/CCL2 Expression

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12 December 2020

Is the invasive front of an oral carcinoma the most important area for prognostication?

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12 December 2020

Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells

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12 December 2020

miR-222 regulates the cell biological behavior of oral squamous cell carcinoma by targeting PUMA.

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12 December 2020

Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes

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12 December 2020

Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation

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12 December 2020

Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells

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12 December 2020

Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion.

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12 December 2020

MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines.

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12 December 2020

Signaling pathways required for matrix metalloproteinase-9 induction by betacellulin in head-and-neck squamous carcinoma cells

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12 December 2020

Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop

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12 December 2020

Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells

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12 December 2020

Head and Neck Cancer Stem Cells

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12 December 2020

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

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12 December 2020

The biology of head and neck cancer stem cells

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12 December 2020

Signal transduction pathways involved in epithelial-mesenchymal transition in oral cancer compared with other cancers.

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12 December 2020

YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.

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12 December 2020

A synthetic matrix metalloproteinase inhibitor prevents squamous carcinoma cell proliferation by interfering with epidermal growth factor receptor autocrine loops

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12 December 2020

Combined inhibition of EMMPRIN and epidermal growth factor receptor prevents the growth and migration of head and neck squamous cell carcinoma cells

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12 December 2020

Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor

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12 December 2020

Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell line

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12 December 2020

Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells

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12 December 2020

Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.

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12 December 2020

FAK and Src expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients survival

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12 December 2020

Knockdown of FAK inhibits the invasion and metastasis of Tca‑8113 cells in vitro

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12 December 2020

Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models

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12 December 2020

Wnt5b promotes the cell motility essential for metastasis of oral squamous cell carcinoma through active Cdc42 and RhoA.

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12 December 2020

Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma

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12 December 2020

Tissue inhibitor of metalloproteinases in oral squamous cell carcinomas - a therapeutic target?

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12 December 2020

A CCL2/ROS autoregulation loop is critical for cancer-associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma

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12 December 2020

Hypoxia-inducible factor-1alpha mediates oral squamous cell carcinoma invasion via upregulation of alpha5 integrin and fibronectin

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12 December 2020

Matrix metalloproteases in head and neck cancer

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12 December 2020

Alphavbeta6-Fyn signaling promotes oral cancer progression.

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12 December 2020

Transforming growth factor-beta 1 promotes matrix metalloproteinase-9-mediated oral cancer invasion through snail expression

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12 December 2020

Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation

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12 December 2020

Cortactin Overexpression Regulates Actin-Related Protein 2/3 Complex Activity, Motility, and Invasion in Carcinomas with Chromosome 11q13 Amplification

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12 December 2020

miR-181a-Twist1 pathway in the chemoresistance of tongue squamous cell carcinoma

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12 December 2020

Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling

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12 December 2020

Role of the alpha(v)beta6 integrin in human oral squamous cell carcinoma growth in vivo and in vitro

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12 December 2020

Collagen XVI induces expression of MMP9 via modulation of AP-1 transcription factors and facilitates invasion of oral squamous cell carcinoma

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12 December 2020

Expression of matriptase correlates with tumour progression and clinical prognosis in oral squamous cell carcinoma.

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12 December 2020

Combined inhibition of PLC{gamma}-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion

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12 December 2020

Analysis of Inflammatory Infiltrate, Perineural Invasion, and Risk Score Can Indicate Concurrent Metastasis in Squamous Cell Carcinoma of the Tongue

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12 December 2020

Snail overexpression induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells

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12 December 2020

MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1.

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12 December 2020

Thrombospondin-1 up-regulates tumor cell invasion through the urokinase plasminogen activator receptor in head and neck cancer cells

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12 December 2020

New functions for the matrix metalloproteinases in cancer progression

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12 December 2020

MicroRNA-138 suppresses epithelial–mesenchymal transition in squamous cell carcinoma cell lines

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12 December 2020

Immunohistochemical study of p53, Ki-67, MMP-2 and MMP-9 expression at invasive front of squamous cell and verrucous carcinoma in oral cavity

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12 December 2020

Tumor suppressive microRNA-133a regulates novel targets: moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma

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12 December 2020

Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma

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12 December 2020

Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis

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12 December 2020

EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression

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12 December 2020

miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene

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12 December 2020

RNAi-mediated downregulation of urokinase plasminogen activator receptor inhibits proliferation, adhesion, migration and invasion in oral cancer cells

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12 December 2020

Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.

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12 December 2020

Matrix metalloproteinase-2 as a target for head and neck cancer therapy

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12 December 2020

Syk/JNK/AP-1 signaling pathway mediates interleukin-6-promoted cell migration in oral squamous cell carcinoma

1 reference

12 December 2020

miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma

1 reference

12 December 2020

Tumor microenvironment in head and neck squamous cell carcinoma.

1 reference

12 December 2020

Exosome secretion is enhanced by invadopodia and drives invasive behavior

1 reference

12 December 2020

Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms.

1 reference

12 December 2020

Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma

1 reference

12 December 2020

Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT‐like phenotype change and MMP‐9‐mediated degradation of E‐cadherin

1 reference

12 December 2020

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

1 reference

12 December 2020

Restoration of caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma.

1 reference

12 December 2020

Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasis

1 reference

12 December 2020

MMP-10/stromelysin-2 promotes invasion of head and neck cancer

1 reference

12 December 2020

Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling

1 reference

12 December 2020

EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments

1 reference

12 December 2020

Epithelial–mesenchymal transition and cancer stemness: the Twist1–Bmi1 connection

1 reference

12 December 2020

Lyn kinase mediates cell motility and tumor growth in EGFRvIII-expressing head and neck cancer

1 reference

12 December 2020

Activation of Toll-like receptor-9 promotes cellular migration via up-regulating MMP-2 expression in oral squamous cell carcinoma

1 reference

12 December 2020

GALNT2 enhances migration and invasion of oral squamous cell carcinoma by regulating EGFR glycosylation and activity

1 reference

12 December 2020

An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.

1 reference

12 December 2020

The UCSC Cancer Genomics Browser: update 2015

1 reference

12 December 2020

Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells

1 reference

12 December 2020

Epithelial-mesenchymal transition during invasion of cutaneous squamous cell carcinoma is paralleled by AKT activation.

1 reference

12 December 2020

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression

1 reference

12 December 2020

Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.

1 reference

12 December 2020

Effects of epidermal growth factor on the invasion activity of the oral cancer cell lines HSC3 and SAS.

1 reference

12 December 2020

Over-expression of integrin-linked kinase correlates with aberrant expression of Snail, E-cadherin and N-cadherin in oral squamous cell carcinoma: implications in tumor progression and metastasis.

1 reference

12 December 2020

A new in vitro model for analyzing the biological behavior of well-differentiated squamous cell carcinoma

1 reference

12 December 2020

Overexpression of miR -155 promotes proliferation and invasion of human laryngeal squamous cell carcinoma via targeting SOCS1 and STAT3.

1 reference

12 December 2020

In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages

1 reference

12 December 2020

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

1 reference

12 December 2020

Insights into the role of components of the tumor microenvironment in oral carcinoma call for new therapeutic approaches.

1 reference

12 December 2020

E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs

1 reference

12 December 2020

PIK3CA Is Critical for the Proliferation, Invasiveness, and Drug Resistance of Human Tongue Carcinoma Cells

1 reference

12 December 2020

Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis

1 reference

12 December 2020

Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas

1 reference

12 December 2020

Notch1 signaling pathway participates in cancer invasion by regulating MMPs in lingual squamous cell carcinoma

1 reference

12 December 2020

Oral squamous cell carcinoma: histologic risk assessment, but not margin status, is strongly predictive of local disease-free and overall survival

1 reference

12 December 2020

Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor

1 reference

12 December 2020

Benzyl isothiocyanate inhibits HNSCC cell migration and invasion, and sensitizes HNSCC cells to cisplatin.

1 reference

12 December 2020

Interleukin-6 directly influences proliferation and invasion potential of head and neck cancer cells

1 reference

12 December 2020

Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer

1 reference

12 December 2020

FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion

1 reference

12 December 2020

Connective tissue growth factor modulates oral squamous cell carcinoma invasion by activating a miR-504/FOXP1 signalling.

1 reference

12 December 2020

Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis

1 reference

12 December 2020

Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation

1 reference

12 December 2020

The RANKL/RANK system as a therapeutic target for bone invasion by oral squamous cell carcinoma (Review).

1 reference

12 December 2020

Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.

1 reference

12 December 2020

A miR-centric view of head and neck cancers

1 reference

12 December 2020

Isolation and characterization of myofibroblast cell lines from oral squamous cell carcinoma.

1 reference

12 December 2020

Epigallocatechin-3 gallate inhibits cancer invasion by repressing functional invadopodia formation in oral squamous cell carcinoma.

1 reference

12 December 2020

Primary tumor staging for oral cancer and a proposed modification incorporating depth of invasion: an international multicenter retrospective study

1 reference

12 December 2020

The kallikrein–kinin-system in head and neck squamous cell carcinoma (HNSCC) and its role in tumour survival, invasion, migration and response to radiotherapy

1 reference

12 December 2020

Activation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells.

1 reference

12 December 2020

MicroRNAs in Head and Neck Cancer

1 reference

12 December 2020

TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?

1 reference

12 December 2020

Down-regulation of the microRNA-99 family members in head and neck squamous cell carcinoma

1 reference

12 December 2020

MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas

1 reference

12 December 2020

Radiation-enhanced cell migration/invasion process: a review.

1 reference

12 December 2020

Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma

1 reference

12 December 2020

Copy number variations and cancer

1 reference

12 December 2020

Role of HGF/c-met system in invasion and metastasis of oral squamous cell carcinoma cells in vitro and its clinical significance

1 reference

12 December 2020

The invasive front of carcinomas. The most important area for tumour prognosis?

1 reference

12 December 2020

Regulation of cancer invasiveness by the physical extracellular matrix environment

1 reference

12 December 2020

10.5858/ARPA.2014-0498-RA

Identifiers

DOI

1 reference

3 September 2017

0 references

1 reference