Class III β-tubulin in normal and cancer tissues (Q38404084)

2 September 2017

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title

Class III β-tubulin in normal and cancer tissues (English)

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2 September 2017

part of the series

Gene Wiki Review Series

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author name string

Marisa Mariani

1

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2 September 2017

Roshan Karki

2

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2 September 2017

Manuela Spennato

3

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2 September 2017

Deep Pandya

4

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2 September 2017

Shiquan He

5

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2 September 2017

Mirko Andreoli

6

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2 September 2017

Paul Fiedler

7

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2 September 2017

Cristiano Ferlini

8

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2 September 2017

language of work or name

English

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publication date

1 April 2015

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2 September 2017

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2 September 2017

volume

563

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2 September 2017

issue

2

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2 September 2017

page(s)

109-114

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Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells'

2 September 2017

cites work

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12 December 2020

Aberrant localization of the neuronal class III beta-tubulin in astrocytomas

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12 December 2020

Class III β‐tubulin in human development and cancer

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12 December 2020

Immunological discrimination of beta-tubulin isoforms in developing mouse brain. Post-translational modification of non-class-III beta-tubulins

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12 December 2020

Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel

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12 December 2020

Podophyllotoxin as a probe for the colchicine binding site of tubulin

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12 December 2020

Epidermal growth factor-responsive laryngeal squamous cancer cell line Hep2 is more sensitive than unresponsive CO-K3 one to quercetin and tamoxifen apoptotic effects.

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12 December 2020

Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology

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12 December 2020

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

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12 December 2020

The role of cysteine residues as redox-sensitive regulatory switches

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12 December 2020

Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients.

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12 December 2020

The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.

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12 December 2020

Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy.

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12 December 2020

Clinical significance of class III beta-tubulin expression and its predictive value for resistance to docetaxel-based chemotherapy in gastric cancer.

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12 December 2020

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

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12 December 2020

The betaI/betaIII-tubulin isoforms and their complexes with antimitotic agents. Docking and molecular dynamics studies

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12 December 2020

Expression of class III beta tubulin in cervical cancer patients administered preoperative radiochemotherapy: correlation with response to treatment and clinical outcome

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12 December 2020

Class III -Tubulin Expression and Benefit from Adjuvant Cisplatin/Vinorelbine Chemotherapy in Operable Non-Small Cell Lung Cancer: Analysis of NCIC JBR.10

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12 December 2020

Expression of beta-tubulin isotypes in human primary ovarian carcinoma

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12 December 2020

Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells

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12 December 2020

Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer

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12 December 2020

Hypoxia induces class III beta-tubulin gene expression by HIF-1alpha binding to its 3' flanking region

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12 December 2020

From plasma membrane to cytoskeleton: a novel function for semaphorin 6A.

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12 December 2020

Looking at drug resistance mechanisms for microtubule interacting drugs: does TUBB3 work?

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12 December 2020

How do microtubule-targeted drugs work? An overview

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12 December 2020

Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin

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12 December 2020

Class III beta-tubulin is constitutively coexpressed with glial fibrillary acidic protein and nestin in midgestational human fetal astrocytes: implications for phenotypic identity

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12 December 2020

The roles of cys124 and ser239 in the functional properties of human betaIII tubulin

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12 December 2020

Class III beta-tubulin isotype predicts response in advanced breast cancer patients randomly treated either with single-agent doxorubicin or docetaxel

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12 December 2020

Proteomic characterization of cytoskeletal and mitochondrial class III beta-tubulin

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12 December 2020

Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with carboplatin and paclitaxel.

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12 December 2020

Molecular mechanisms of patupilone resistance

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12 December 2020

Loss of class III beta-tubulin induced by histone deacetylation is associated with chemosensitivity to paclitaxel in malignant melanoma cells

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12 December 2020

Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer

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12 December 2020

Overexpression of class III beta-tubulin predicts good response to taxane-based chemotherapy in ovarian clear cell adenocarcinoma

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12 December 2020

Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin

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12 December 2020

Beta3-tubulin is induced by estradiol in human breast carcinoma cells through an estrogen-receptor dependent pathway.

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12 December 2020

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. II. gamma-Tubulin

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12 December 2020

Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77

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12 December 2020

Increased expression of class III beta-tubulin in castration-resistant human prostate cancer

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12 December 2020

Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin

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12 December 2020

Possible regulation of the in vitro assembly of bovine brain tubulin by the bovine thioredoxin system

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12 December 2020

Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance

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12 December 2020

Expression of class III beta-tubulin correlates with unfavorable survival outcome in patients with resected non-small cell lung cancer

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12 December 2020

Differential expression and cellular distribution of gamma-tubulin and betaIII-tubulin in medulloblastomas and human medulloblastoma cell lines

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12 December 2020

Class III beta-tubulin shows unique expression patterns in a variety of neoplastic and non-neoplastic lymphoproliferative disorders

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12 December 2020

betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer

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12 December 2020

Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget disease

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12 December 2020

HuR regulates beta-tubulin isotype expression in ovarian cancer

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12 December 2020

Mutations in the neuronal ß-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects

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12 December 2020

Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy.

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12 December 2020

The miR-200 family controls -tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients

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12 December 2020

Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development

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12 December 2020

Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials

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12 December 2020

Is class III beta-tubulin a true predictive marker of sensitivity to vinorelbine in non-small cell lung cancer? Chemosensitivity data evidence

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12 December 2020

Class III β-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer

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12 December 2020

Targeting βIII-tubulin in glioblastoma multiforme: from cell biology and histopathology to cancer therapeutics

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12 December 2020

Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells

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12 December 2020

A Novel Xenogeneic Co-Culture System to Examine Neuronal Differentiation Capability of Various Adult Human Stem Cells

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12 December 2020

RT-PCR versus immunohistochemistry for correlation and quantification of ERCC1, BRCA1, TUBB3 and RRM1 in NSCLC

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12 December 2020

Transcriptional and post-transcriptional regulation of βIII-tubulin protein expression in relation with cell cycle-dependent regulation of tumor cells

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12 December 2020

Differential in vitro sensitivity to patupilone versus paclitaxel in uterine and ovarian carcinosarcoma cell lines is linked to tubulin-beta-III expression

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12 December 2020

Association between class III β-tubulin expression and response to paclitaxel/vinorebine-based chemotherapy for non-small cell lung cancer: a meta-analysis

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12 December 2020

Tubulins as therapeutic targets in cancer: from bench to bedside

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12 December 2020

Novel drugs targeting microtubules: the role of epothilones.

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12 December 2020

High TUBB3 expression, an independent prognostic marker in patients with early non-small cell lung cancer treated by preoperative chemotherapy, is regulated by K-Ras signaling pathway.

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12 December 2020

Gender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancer.

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12 December 2020

The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis

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12 December 2020

Clinical implications of REST and TUBB3 in ovarian cancer and its relationship to paclitaxel resistance

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12 December 2020

Randomized, Open-Label, Phase III Study Comparing Patupilone (EPO906) With Pegylated Liposomal Doxorubicin in Platinum-Refractory or -Resistant Patients With Recurrent Epithelial Ovarian, Primary Fallopian Tube, or Primary Peritoneal Cancer

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12 December 2020

High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer

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12 December 2020

βIII-Tubulin: biomarker of taxane resistance or drug target?

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12 December 2020

MiR-200c and HuR in ovarian cancer

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12 December 2020

Free testosterone drives cancer aggressiveness: evidence from US population studies

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12 December 2020

A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.

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12 December 2020

Class III β-tubulin overexpression within the tumor microenvironment is a prognostic biomarker for poor overall survival in ovarian cancer patients treated with neoadjuvant carboplatin/paclitaxel

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12 December 2020

Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdown

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12 December 2020

βIII-tubulin overexpression is an independent predictor of prostate cancer progression tightly linked to ERG fusion status and PTEN deletion

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12 December 2020

Plasma testosterone in the general population, cancer prognosis and cancer risk: a prospective cohort study

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12 December 2020

Sox9 and Hif-2α regulate TUBB3 gene expression and affect ovarian cancer aggressiveness

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12 December 2020

Immunohistochemistry of a spontaneous murine ovarian teratoma with neuroepithelial differentiation. Neuron-associated beta-tubulin as a marker for primitive neuroepithelium

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12 December 2020

Expression of neural markers by undifferentiated mesenchymal-like stem cells from different sources

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12 December 2020

Association of ABCB1, β tubulin I, and III with multidrug resistance of MCF7/DOC subline from breast cancer cell line MCF7.

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12 December 2020

GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1.

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12 December 2020

Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells.

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12 December 2020

TUBB3/βIII-tubulin acts through the PTEN/AKT signaling axis to promote tumorigenesis and anoikis resistance in non-small cell lung cancer

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12 December 2020

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes

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12 December 2020

Oxygen-collagen priority and the early metazoan fossil record

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12 December 2020

Microtubule dynamics in vitro are regulated by the tubulin isotype composition

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12 December 2020

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes

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12 December 2020

Effects of podophyllotoxin and VP-16-213 on microtubule assembly in vitro and nucleoside transport in HeLa cells

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12 December 2020

10.1016/J.GENE.2015.03.061

Identifiers

DOI

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2 September 2017

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