The importance of co-stimulation in the orchestration of T helper cell differentiation (Q38388255)

2 September 2017

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title

The importance of co-stimulation in the orchestration of T helper cell differentiation (English)

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2 September 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Lisa Rausch

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

Jannie Borst

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

publication date

24 March 2015

1 reference

Immunology & Cell Biology

2 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

volume

93

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

780-788

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801480 AND SRC:MED&resulttype=core&format=json

T-cell development and the CD4-CD8 lineage decision

7 June 2020

cites work

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The role of ThPOK in control of CD4/CD8 lineage commitment

21 January 2018

1 reference

Control of regulatory T cell lineage commitment and maintenance

21 January 2018

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Epigenetic control of T-helper-cell differentiation

21 January 2018

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21 January 2018

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The origins, function, and regulation of T follicular helper cells

21 January 2018

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Heterogeneity and plasticity of T helper cells

21 January 2018

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Plasticity of CD4 T cell lineage differentiation.

21 January 2018

1 reference

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

21 January 2018

1 reference

CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4 T helper 1 cell differentiation

21 January 2018

1 reference

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

21 January 2018

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Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

21 January 2018

1 reference

Phenotypic and functional features of human Th17 cells

21 January 2018

1 reference

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

21 January 2018

1 reference

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

21 January 2018

1 reference

A validated regulatory network for Th17 cell specification

21 January 2018

1 reference

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

1 reference

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 T helper cells

21 January 2018

1 reference

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

1 reference

Inducible Foxp3 regulatory T-cell development by a commensal bacterium of the intestinal microbiota

21 January 2018

1 reference

The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node

21 January 2018

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Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

21 January 2018

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

21 January 2018

1 reference

T-cell activation by dendritic cells in the lymph node: lessons from the movies

21 January 2018

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Stochastic cytokine expression induces mixed T helper cell States

21 January 2018

1 reference

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory

21 January 2018

1 reference

Early Th1 cell differentiation is marked by a Tfh cell-like transition

21 January 2018

1 reference

Genomic views of STAT function in CD4 T helper cell differentiation

21 January 2018

1 reference

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 T cells

21 January 2018

1 reference

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

21 January 2018

1 reference

Induction of Th1/Th17 immune response by Mycobacterium tuberculosis: role of dectin-1, Mannose Receptor, and DC-SIGN.

21 January 2018

1 reference

Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.

21 January 2018

1 reference

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

21 January 2018

1 reference

Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells

21 January 2018

1 reference

IRF4 transcription-factor-dependent CD103( )CD11b( ) dendritic cells drive mucosal T helper 17 cell differentiation.

21 January 2018

1 reference

A functionally specialized population of mucosal CD103 DCs induces Foxp3 regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses

21 January 2018

1 reference

ATP drives lamina propria T(H)17 cell differentiation

21 January 2018

1 reference

Conventional and monocyte-derived CD11b( ) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen

21 January 2018

1 reference

TCR signal quantity and quality in CD4( ) T cell differentiation.

21 January 2018

1 reference

Molecular mechanisms of T cell co-stimulation and co-inhibition

21 January 2018

1 reference

CD28-mediated co-stimulation: a quantitative support for TCR signalling

21 January 2018

1 reference

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

21 January 2018

1 reference

Expression of the murine CD27 ligand CD70 in vitro and in vivo

21 January 2018

1 reference

Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules

21 January 2018

1 reference

CD27 instructs CD4 T cells to provide help for the memory CD8 T cell response after protein immunization

21 January 2018

1 reference

The CD4⁺ T-cell help signal is transmitted from APC to CD8⁺ T-cells via CD27-CD70 interactions

21 January 2018

1 reference

Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3 CD4 regulatory T cells

21 January 2018

1 reference

Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70.

21 January 2018

1 reference

Metabolic regulation of T lymphocytes

21 January 2018

1 reference

Rapamycin promotes expansion of functional CD4 CD25 FOXP3 regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

1 reference

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

21 January 2018

1 reference

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

21 January 2018

1 reference

IL-2 Controls the Stability of Foxp3 Expression in TGF-β–Induced Foxp3 T Cells In Vivo

21 January 2018

1 reference

T-cell-receptor-dependent signal intensity dominantly controls CD4( ) T cell polarization In Vivo

21 January 2018

1 reference

CD27-CD70 interactions sensitise naive CD4 T cells for IL-12-induced Th1 cell development.

21 January 2018

1 reference

A subset of dendritic cells induces CD4 T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.

21 January 2018

1 reference

The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity

21 January 2018

1 reference

Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion

21 January 2018

1 reference

BATF-JUN is critical for IRF4-mediated transcription in T cells

21 January 2018

1 reference

Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

21 January 2018

1 reference

CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1

21 January 2018

1 reference

OX40 (CD134) and OX40 ligand interaction plays an adjuvant role during in vivo Th2 responses.

21 January 2018

1 reference

Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment

21 January 2018

1 reference

OX40 signaling favors the induction of T(H)9 cells and airway inflammation

21 January 2018

1 reference

Transcriptional regulation of th2 differentiation by inducible costimulator

21 January 2018

1 reference

ICOS co-stimulatory receptor is essential for T-cell activation and function

21 January 2018

1 reference

ICOS is essential for effective T-helper-cell responses

21 January 2018

1 reference

Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation

21 January 2018

1 reference

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

21 January 2018

1 reference

c-Maf regulates IL-10 expression during Th17 polarization

21 January 2018

1 reference

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

1 reference

The transcription factor STAT3 is required for T helper 2 cell development

21 January 2018

1 reference

IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation.

21 January 2018

1 reference

CREB-binding protein/p300 co-activation of crystallin gene expression

21 January 2018

1 reference

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

21 January 2018

1 reference

Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2.

21 January 2018

1 reference

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

21 January 2018

1 reference

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8 T cells

21 January 2018

1 reference

CD8 T cells produce the chemokine CXCL10 in response to CD27/CD70 costimulation to promote generation of the CD8 effector T cell pool

21 January 2018

1 reference

Regulation of T(H)2 development by CXCR5 dendritic cells and lymphotoxin-expressing B cells

21 January 2018

1 reference

B Cell-Specific Expression of B7-2 Is Required for Follicular Th Cell Function in Response to Vaccinia Virus

21 January 2018

1 reference

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

21 January 2018

1 reference

The role of ICOS in the CXCR5 follicular B helper T cell maintenance in vivo

21 January 2018

1 reference

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

21 January 2018

1 reference

T follicular helper (TFH) cells in normal and dysregulated immune responses

21 January 2018

1 reference

Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

21 January 2018

1 reference

Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.

21 January 2018

1 reference

Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer

21 January 2018

1 reference

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

21 January 2018

1 reference

OX40L blockade and allergen-induced airway responses in subjects with mild asthma

21 January 2018

1 reference

Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27.

21 January 2018

1 reference

CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

21 January 2018

1 reference

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

21 January 2018

1 reference

Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood

21 January 2018

1 reference

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

21 January 2018

1 reference

Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model.

21 January 2018

1 reference

Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells

21 January 2018

1 reference

12 December 2020

OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4( ) T cells into high IL-4-producing effectors

1 reference

12 December 2020

Regulation of CD27 expression on subsets of mature T-lymphocytes

1 reference

12 December 2020

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

1 reference

12 December 2020

1 reference

12 December 2020

The antigen dose determines T helper subset development by regulation of CD40 ligand

1 reference

12 December 2020

Cutting edge: Th2 response induction by dendritic cells: a role for CD40

1 reference

12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

1 reference

12 December 2020

Inducible T cell antigen 4-1BB. Analysis of expression and function

1 reference

12 December 2020

IL-33-activated dendritic cells are critical for allergic airway inflammation

1 reference

12 December 2020

IL-12 up-regulates T-bet independently of IFN-gamma in human CD4 T cells

1 reference

12 December 2020

Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition

1 reference

12 December 2020

Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo

1 reference

7 January 2021