Neuroprotective therapies for glaucoma. (Q38384978)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

review article

2 references

26 January 2021

Neuroprotective therapies for glaucoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

25 April 2019

neuroprotective agent

1 reference

26 January 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Ping Huang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

Chun Zhang

series ordinal

3

1 reference

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3 March 2020

language of work or name

English

0 references

publication date

11 March 2015

3 references

25 April 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

26 January 2021

Drug Design, Development and Therapy

3 references

25 April 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

26 January 2021

9

1 reference

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3 March 2020

page(s)

1469-1479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial

3 March 2020

copyright license

2 references

25 April 2019

26 January 2021

on focus list of Wikimedia project

ScienceSource

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cites work

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Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model

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Minocycline upregulates pro-survival genes and downregulates pro-apoptotic genes in experimental glaucoma

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Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress-mediated mitochondrial alteration in a mouse model of glaucoma

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Lycium barbarum (wolfberry) reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection.

6 September 2017

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Challenges in the development of glaucoma neuroprotection therapy

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Neuro-protection of retinal stem cells transplantation combined with copolymer-1 immunization in a rat model of glaucoma

6 September 2017

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Etanercept, a widely used inhibitor of tumor necrosis factor-α (TNF-α), prevents retinal ganglion cell loss in a rat model of glaucoma

6 September 2017

1 reference

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Definition of glaucoma: clinical and experimental concepts

6 September 2017

1 reference

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Transplantation of BDNF-secreting mesenchymal stem cells provides neuroprotection in chronically hypertensive rat eyes

6 September 2017

1 reference

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Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: Implications for glaucoma

6 September 2017

1 reference

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Effect of CNTF on retinal ganglion cell survival in experimental glaucoma

6 September 2017

1 reference

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Protective autoimmunity in the nervous system

6 September 2017

1 reference

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Reduced NGF level and TrkA protein and TrkA gene expression in the optic nerve of rats with experimentally induced glaucoma

6 September 2017

1 reference

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A placebo-controlled 3-year study of a calcium blocker on visual field and ocular circulation in glaucoma with low-normal pressure

6 September 2017

1 reference

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Apoptosis: a review of programmed cell death

6 September 2017

1 reference

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Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma

6 September 2017

1 reference

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The number of people with glaucoma worldwide in 2010 and 2020

6 September 2017

1 reference

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Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures

6 September 2017

1 reference

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Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures

6 September 2017

1 reference

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Pharmacologic neuroprotection with an inhibitor of nitric oxide synthase for the treatment of glaucoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Antigenic specificity of immunoprotective therapeutic vaccination for glaucoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Hypothesis for a common basis for neuroprotection in glaucoma and Alzheimer's disease: anti-apoptosis by alpha-2-adrenergic receptor activation

6 September 2017

1 reference

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Neurotrophins and their receptors: a convergence point for many signalling pathways

6 September 2017

1 reference

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Expression and activation of STAT proteins during mouse retina development

6 September 2017

1 reference

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Neuroprotective effect of memantine in different retinal injury models in rats

6 September 2017

1 reference

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Microglia as neuroprotective, immunocompetent cells of the CNS.

6 September 2017

1 reference

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Up-regulation of brain-derived neurotrophic factor expression by brimonidine in rat retinal ganglion cells

6 September 2017

1 reference

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Neurotrophins as synaptic modulators

6 September 2017

1 reference

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Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucoma

6 September 2017

1 reference

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GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle

6 September 2017

1 reference

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Delayed increase of Ca2 influx elicited by glutamate: role in neuronal death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

The nerve growth factor 35 years later

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

The prevalence and types of glaucoma in an urban Indian population: the Singapore Indian Eye Study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Prevalence of primary open angle glaucoma in a rural adult Chinese population: the Handan eye study.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Antioxidant effect of a Ginkgo biloba extract (EGb 761) on the retina

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Epidemiology of glaucoma in Japan--a nationwide glaucoma survey

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Improved retinal ganglion cell survival through retinal microglia suppression by a chinese herb extract, triptolide, in the DBA/2J mouse model of glaucoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Effect of Ginkgo biloba extract on visual field progression in normal tension glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Copolymer-1 immunization reduces damage in retinal ganglion cells under high intraocular pressure through altering the expression of retinal neurotrophins

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Retinal concentration and protective effect against retinal ischemia of nilvadipine in rats.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Minocycline delays death of retinal ganglion cells in experimental glaucoma and after optic nerve transection

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Protective effects of various antioxidants during ischemia-reperfusion in the rat retina

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

The Ginkgo biloba extract (EGb 761) provides a neuroprotective effect on retinal ganglion cells in a rat model of chronic glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Neurodegeneration and neuroprotection in glaucoma: development of a therapeutic neuroprotective vaccine: the Friedenwald lecture

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Effect of Ginkgo biloba extract on preexisting visual field damage in normal tension glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Betaxolol, a beta1-adrenoceptor antagonist, protects a transient ischemic injury of the retina

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

A prodrug of a selective inhibitor of inducible nitric oxide synthase is neuroprotective in the rat model of glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Role of alpha-2 adrenergic receptors in neuroprotection and glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Patterns of retinal ganglion cell survival after brain-derived neurotrophic factor administration in hypertensive eyes of rats

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

MK801-a neuroprotectant in rat hypertensive eyes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

TUNEL-Positive Ganglion Cells in Human Primary Open-angle Glaucoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Nitric oxide synthase in the human glaucomatous optic nerve head.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362661

Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma

31 August 2018

1 reference

12 December 2020

Lomerizine, a Ca2 channel blocker, reduces glutamate-induced neurotoxicity and ischemia/reperfusion damage in rat retina

1 reference

12 December 2020

A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study

1 reference

12 December 2020

A rat model for acute rise in intraocular pressure: immune modulation as a therapeutic strategy

1 reference

12 December 2020

Chronology of optic nerve head and retinal responses to elevated intraocular pressure

1 reference

12 December 2020

Expression of nitric oxide synthase-2 (NOS-2) in reactive astrocytes of the human glaucomatous optic nerve head

1 reference

12 December 2020

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis

1 reference

12 December 2020

Longterm effect of topical beta-blockers on intraocular pressure and visual field sensitivity in ocular hypertension and chronic open-angle glaucoma

1 reference

12 December 2020

Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma

1 reference

12 December 2020

Retinal Damage Caused by High Intraocular Pressure–Induced Transient Ischemia is Prevented by Coenzyme Q10 in Rat

1 reference

12 December 2020

Mechanisms of ocular neuroprotection by antioxidant molecules in animal models

1 reference

12 December 2020

Protective effects of flunarizine on ischemic injury in the rat retina

1 reference

12 December 2020

BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons

1 reference

12 December 2020

Antioxidant effects of alpha-, gamma- and succinate-tocopherols in guinea pig retina during ischemia-reperfusion injury

1 reference

12 December 2020

Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats

1 reference

12 December 2020

Effect of Ginkgo biloba on visual field and contrast sensitivity in Chinese patients with normal tension glaucoma: a randomized, crossover clinical trial

1 reference

12 December 2020

Identifiers

DOI

10.2147/DDDT.S80863

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25792807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25792807 AND SRC:MED&resulttype=core&format=json