Ikaros and leukaemia (Q38371003)

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English	Ikaros and leukaemia	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

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Europe PubMed Central

Ikaros and leukaemia (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

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based on heuristic

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author name string

Linda Olsson

1

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Europe PubMed Central

PubMed publication ID

2 September 2017

Bertil Johansson

2

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Europe PubMed Central

PubMed publication ID

2 September 2017

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publication date

5 March 2015

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Europe PubMed Central

PubMed publication ID

2 September 2017

British Journal of Haematology

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Europe PubMed Central

PubMed publication ID

2 September 2017

169

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Europe PubMed Central

PubMed publication ID

2 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

479-491

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros confers early temporal competence to mouse retinal progenitor cells

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

An essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary-mediated somatic growth

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Tumor-derived Ikaros 6 acetylates the Bcl-XL promoter to up-regulate a survival signal in pituitary cells

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Regulator of myeloid differentiation and function: The secret life of Ikaros

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

The Ikaros gene is required for the development of all lymphoid lineages

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros gene

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKZF1: a critical role in the pathogenesis of systemic lupus erythematosus?

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Deletions of the transcription factor Ikaros in myeloproliferative neoplasms.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Multiple hematopoietic defects and delayed globin switching in Ikaros null mice

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Cloning and analysis of the human Pax-5 gene promoter

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Relative expression of different Ikaros isoforms in childhood acute leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Acute lymphoblastic leukemia in a patient with Greig cephalopolysyndactyly and interstitial deletion of chromosome 7 del(7)(p11.2 p14) involving the GLI3 and ZNFN1A1 genes

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

JAK mutations in high-risk childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Deletions of immunoglobulin heavy chain and T cell receptor gene regions are uniquely associated with lymphoid blast transformation of chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros isoform x is selectively expressed in myeloid differentiation.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Genetic variants modify susceptibility to leukemia in infants: a Children's Oncology Group report

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Overexpression of the Ikaros 6 isoform is restricted to t(4;11) acute lymphoblastic leukaemia in children and infants and has a role in B-cell survival

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Forced expression of the Ikaros 6 isoform in human placental blood CD34( ) cells impairs their ability to differentiate toward the B-lymphoid lineage

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Germline genomic variants associated with childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Highly sensitive MRD tests for ALL based on the IKZF1 Δ3-6 microdeletion

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Are ARID5B and IKZF1 polymorphisms also associated with childhood acute myeloblastic leukemia: the ESCALE study (SFCE)?

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols

1 reference

https://api.crossref.org/works/10.1111/BJH.13342

21 January 2018

Identifiers

10.1111/BJH.13342

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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