A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation. (Q38365327)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318044 AND SRC:MED&resulttype=core&format=json

2 March 2020

title

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation (English)

1 reference

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2 March 2020

8

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2 March 2020

Jennifer Munkley

1

1 reference

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2 March 2020

Prabhakar Rajan

2

1 reference

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2 March 2020

Hing Y Leung

7

1 reference

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2 March 2020

author name string

Nicholas P Lafferty

3

1 reference

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2 March 2020

Caroline Dalgliesh

4

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2 March 2020

Robert M Jackson

5

1 reference

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2 March 2020

Craig N Robson

6

1 reference

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2 March 2020

language of work or name

English

0 references

publication date

1 January 2014

1 reference

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2 March 2020

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2 March 2020

volume

5

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2 March 2020

issue

1

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2 March 2020

page(s)

131-139

1 reference

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describes a project that uses

2 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3960195/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome

1 reference

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Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis

6 September 2017

1 reference

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Alternatively spliced androgen receptor variants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The tuberous sclerosis complex: balancing proliferation and survival

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

6 September 2017

1 reference

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Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival

6 September 2017

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Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis

6 September 2017

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Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

6 September 2017

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The tuberous sclerosis complex

6 September 2017

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Alternative splicing and biological heterogeneity in prostate cancer

6 September 2017

1 reference

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Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The functional consequences of alternative promoter use in mammalian genomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partners

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Defining the role of mTOR in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Tuberin nuclear localization can be regulated by phosphorylation of its carboxyl terminus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Rheb fills a GAP between TSC and TOR.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Frequent hypermethylation of the RASSF1A gene in prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

The tuberous sclerosis 2 gene product can localize to nuclei in a phosphorylation-dependent manner

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Subcellular distribution of the TSC2 gene product tuberin in human airway smooth muscle cells is driven by multiple localization sequences and is cell-cycle dependent

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Cross-talk between tuberin, calmodulin, and estrogen signaling pathways

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3960195

Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24318044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24318044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.1405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318044 AND SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318044 AND SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24318044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318044 AND SRC:MED&resulttype=core&format=json