Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantages (Q38360822)

2 September 2017

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title

Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantages (English)

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2 September 2017

author

Premendu Prakash Mathur

4

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2 September 2017

Ana C Moreira

2

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Pedro F. Oliveira

object named as

Pedro F Oliveira

5

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Mário Sousa

object named as

Mário Sousa

3

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Marco G. Alves

object named as

Marco G Alves

6

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author name string

Mariana M S Reis

1

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2 September 2017

language of work or name

English

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publication date

18 February 2015

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Journal of Applied Toxicology

2 September 2017

published in

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2 September 2017

volume

35

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2 September 2017

issue

8

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2 September 2017

page(s)

870-883

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Effect of lead on Sertoli-germ cell coculture of rat.

2 September 2017

cites work

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Relationship between iron-catalysed lipid peroxidation potential and human sperm function.

21 January 2018

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Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function

21 January 2018

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Molecular mechanisms beyond glucose transport in diabetes-related male infertility.

21 January 2018

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Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

21 January 2018

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Hormonal control of Sertoli cell metabolism regulates spermatogenesis

21 January 2018

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Metformin and male reproduction: effects on Sertoli cell metabolism

21 January 2018

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2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced cytotoxicity accompanied by oxidative stress in rat Sertoli cells: Possible role of mitochondrial fractions of Sertoli cells

21 January 2018

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Impaired semen quality associated with environmental DDT exposure in young men living in a malaria area in the Limpopo Province, South Africa

21 January 2018

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Effect of lead acetate on Sertoli cell lactate production and protein synthesis in vitro

21 January 2018

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Connexin43 gene expression and regulation in the rodent seminiferous epithelium

21 January 2018

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Reproductive and endocrine function in rams exposed to the organochlorine pesticides lindane and pentachlorophenol from conception

21 January 2018

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Oral (gavage) two-generation (one litter per generation) reproduction study of pentachlorophenol (penta) in rats

21 January 2018

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Toxicity testing: creating a revolution based on new technologies

21 January 2018

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Nanomaterials and nanoparticles: sources and toxicity

21 January 2018

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Growth and characterization of polarized monolayers of epididymal epithelial cells and Sertoli cells in dual environment culture chambers

21 January 2018

1 reference

Reproductive toxicity and pharmacokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Effects of high doses on the fertility of male rats

21 January 2018

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The effects of tri-o-cresyl phosphate and metabolites on rat Sertoli cell function in primary culture.

21 January 2018

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Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development

21 January 2018

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Study on the formation of specialized inter-Sertoli cell junctions in vitro

21 January 2018

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Early hypothyroidism in rats causes increased adult testis and reproductive organ size but does not change testosterone levels

21 January 2018

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Reproductive toxicity and tissue concentrations of lindane in adult male rats.

21 January 2018

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Disruption of gap junctional intercellular communication by lindane is associated with aberrant localization of connexin43 and zonula occludens-1 in 42GPA9 Sertoli cells.

21 January 2018

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Human testis steroidogenesis is inhibited by phthalates.

21 January 2018

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Sperm glucose transport and metabolism in diabetic individuals

21 January 2018

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White tea as a promising antioxidant medium additive for sperm storage at room temperature: a comparative study with green tea.

21 January 2018

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Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility

21 January 2018

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Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene

21 January 2018

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A review of three-dimensional in vitro tissue models for drug discovery and transport studies

21 January 2018

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A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones

21 January 2018

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Exposure to TCDD during development permanently alters reproductive function in male Long Evans rats and hamsters: reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status.

21 January 2018

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Interactions between germ cells and Sertoli cells in the testis

21 January 2018

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Are in vitro tests suitable for regulatory use?

21 January 2018

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Phthalate ester effects on rat Sertoli cell function in vitro: effects of phthalate side chain and age of animal

21 January 2018

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Spermatogenesis and cycle of the seminiferous epithelium

21 January 2018

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Cadmium in vivo causes disruption of tight junction-associated microfilaments in rat Sertoli cells

21 January 2018

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Lead exposure causes generation of reactive oxygen species and functional impairment in rat sperm

21 January 2018

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In vitro effects of metal ions (Fe2 , Mn2 , Pb2 ) on sperm motility and lipid peroxidation in human semen

21 January 2018

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Reduced seminal parameters associated with environmental DDT exposure and p,p'-DDE concentrations in men in Chiapas, Mexico: a cross-sectional study

21 January 2018

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Regulation of transepithelial electrical resistance in two-compartment Sertoli cell cultures: in vitro model of the blood-testis barrier.

21 January 2018

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The influence of occupational exposure on male reproductive function

21 January 2018

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Plants for male fertility regulation

21 January 2018

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Assessment of semen function and lipid peroxidation among lead exposed men.

21 January 2018

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Autometallographic detection of mercury in testicular tissue of an infertile man exposed to mercury vapor

21 January 2018

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Structural characteristics of immature rat sertoli cellsin vivo andin vitro

21 January 2018

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Multiple purinergic receptors lead to intracellular calcium increases in cultured rat Sertoli cells

21 January 2018

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Effect of Aroclor 1254 on Sertoli cellular antioxidant system, androgen binding protein and lactate in adult rat in vitro

21 January 2018

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Potential antifertility agents from plants: a comprehensive review

21 January 2018

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The use of 3-D cultures for high-throughput screening: the multicellular spheroid model

21 January 2018

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Effects of TCDD in modulating the expression of Sertoli cell secretory products and markers for cell-cell interaction

21 January 2018

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1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway

21 January 2018

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An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential

21 January 2018

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Urine bisphenol-A (BPA) level in relation to semen quality

21 January 2018

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Effects of Ni(II) and Cu(II) on DNA interaction with the N-terminal sequence of human protamine P2: enhancement of binding and mediation of oxidative DNA strand scission and base damage

21 January 2018

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Effect of mono-(2-ethylhexyl)phthalate on follicle-stimulating hormone responsiveness of cultured rat Sertoli cells

21 January 2018

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Potential new targets involved in 1,3-dinitrobenzene induced testicular toxicity

21 January 2018

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In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability

21 January 2018

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Induction of sister chromatid exchanges by 2,4-dichlorophenoxyacetic acid in somatic and germ cells of mice exposed in vivo.

21 January 2018

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Some aspects relating to the evaluation of the effects of chemicals on male fertility

21 January 2018

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Effect of white tea (Camellia sinensis (L.)) extract in the glycolytic profile of Sertoli cell.

21 January 2018

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Physiology of na /h exchangers in the male reproductive tract: relevance for male fertility

21 January 2018

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Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

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The effect of environmental contaminants on testicular function

21 January 2018

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Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene

21 January 2018

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Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic

21 January 2018

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Influence of gossypol on the secretory function of cultured rat sertoli cells

21 January 2018

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An in vitro system to study Sertoli cell blood-testis barrier dynamics

21 January 2018

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Emerging role for drug transporters at the blood-testis barrier

21 January 2018

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The inhibitory effects of polychlorinated biphenyl Aroclor 1254 on Leydig cell LH receptors, steroidogenic enzymes and antioxidant enzymes in adult rats

21 January 2018

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Effects of polychlorinated biphenyl (Aroclor 1254) on steroidogenesis and antioxidant system in cultured adult rat Leydig cells

21 January 2018

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The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of steroidogenic capacity in rat Leydig cells

21 January 2018

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The Warburg effect revisited--lesson from the Sertoli cell

21 January 2018

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The third dimension bridges the gap between cell culture and live tissue

21 January 2018

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Bisphenol A-induced increase in uterine weight and alterations in uterine morphology in ovariectomized B6C3F1 mice: role of the estrogen receptor

21 January 2018

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The male reproductive system and its susceptibility to endocrine disrupting chemicals

21 January 2018

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Establishment of a rat Sertoli cell line that displays the morphological and some of the functional characteristics of the native cell

21 January 2018

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Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.

21 January 2018

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Metabolic regulation is important for spermatogenesis.

21 January 2018

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The effects of an in utero exposure to 2,3,7,8-tetrachloro-dibenzo-p-dioxin on male reproductive function: identification of Ccl5 as a potential marker

21 January 2018

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Serum and testicular testosterone and androgen binding protein profiles following subchronic treatment with carbendazim

21 January 2018

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Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate.

21 January 2018

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Molecular mechanisms involved in Sertoli cell adaptation to glucose deprivation.

21 January 2018

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Immuno- and bioactive inhibin and inhibin alpha-subunit expression in rat Leydig cell cultures

21 January 2018

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Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility.

21 January 2018

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In vitro testicular toxicity models: opportunities for advancement via biomedical engineering techniques

21 January 2018

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Induction of oxidative stress by lindane in epididymis of adult male rats

21 January 2018

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Single exposure to low dose of lindane causes transient decrease in testicular steroidogenesis in adult male Wistar rats

21 January 2018

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Lindane induces testicular apoptosis in adult Wistar rats through the involvement of Fas-FasL and mitochondria-dependent pathways

21 January 2018

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Light and electron microscopic study of the toxic effect of prolonged lead exposure on the seminiferous tubules of albino rats and the possible protective effect of ascorbic acid

21 January 2018

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p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway

21 January 2018

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Cell-cell interactions in the testis

21 January 2018

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Lead toxicity and the hypothalamic-pituitary-testicular axis

21 January 2018

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The inhibin B response to the testicular toxicant 1, 3 dinitrobenzene in male rats

21 January 2018

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p,p'-DDE induces mitochondria-mediated apoptosis of cultured rat Sertoli cells

21 January 2018

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Neonatal hypothyroidism alters the localization of gap junctional protein connexin 43 in the testis and messenger RNA levels in the epididymis of the rat.

21 January 2018

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Sensitivity of Sertoli and Leydig cells to xenobiotics in in vitro models

21 January 2018

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Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis barrier

21 January 2018

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Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines

21 January 2018

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Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men

21 January 2018

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Epidemiological evidence on reproductive effects of persistent organochlorines in humans

21 January 2018

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Long-lasting effects of lindane on mouse spermatogenesis induced by in utero exposure

21 January 2018

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2,4-Dichlorophenoxyacetic acid effects on nephrotoxicity in rats during late pregnancy and early postnatal periods

21 January 2018

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FSH and testosterone signaling in Sertoli cells

21 January 2018

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Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

21 January 2018

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The effects of 1,3-dinitrobenzene and mono-(2-ethylhexyl)phthalate on hormonally stimulated lactate and pyruvate production by rat Sertoli cell cultures

21 January 2018

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Adverse effects of low level heavy metal exposure on male reproductive function

21 January 2018

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Regulation of blood-testis barrier dynamics: an in vivo study

21 January 2018

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Male reproductive toxicology: comparison of the human to animal models

21 January 2018

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Effects of p,p'-dichlorodiphenyldichloroethylene on the expressions of transferrin and androgen-binding protein in rat Sertoli cells

21 January 2018

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The toxic effects of pentachlorophenol on rat Sertoli cells in vitro

21 January 2018

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Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates

21 January 2018

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No animals harmed: toward a paradigm shift in toxicity testing

21 January 2018

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Effects of thallium on primary cultures of testicular cells

21 January 2018

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Essential Role of Extracellular Matrix (ECM) Overlay in Establishing the Functional Integrity of Primary Neonatal Rat Sertoli Cell/Gonocyte Co-cultures: An Improved In Vitro Model for Assessment of Male Reproductive Toxicity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JAT.3122

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2 September 2017

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