Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses (Q38336111)

2 September 2017

title

Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses (English)

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2 September 2017

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3

Andrej Shevchenko

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2 September 2017

2

Anna Shevchenko

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2 September 2017

4

William G Dunphy

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2 September 2017

Hae Yong Yoo

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2 September 2017

language of work or name

English

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publication date

22 September 2004

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Journal of Biological Chemistry

2 September 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

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2 September 2017

volume

279

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2 September 2017

issue

51

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2 September 2017

page(s)

53353-53364

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A unified view of the DNA-damage checkpoint

2 September 2017

cites work

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Cell cycle checkpoint signaling through the ATM and ATR kinases

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Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

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DNA replication in eukaryotic cells

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MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.

21 January 2018

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MCM proteins: DNA damage, mutagenesis and repair

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Eukaryotic MCM proteins: beyond replication initiation

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Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus

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The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts

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Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

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Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage

21 January 2018

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Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

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Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

21 January 2018

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The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

21 January 2018

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Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity

21 January 2018

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Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase

21 January 2018

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

21 January 2018

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An analysis of the regulation of DNA synthesis by cdk2, Cip1, and licensing factor

21 January 2018

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UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress

21 January 2018

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Isolation and characterization of Xenopus ATM (X-ATM): expression, localization, and complex formation during oogenesis and early development

21 January 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

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Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

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Identification of MCM4 as a Target of the DNA Replication Block Checkpoint System

21 January 2018

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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

21 January 2018

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A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

21 January 2018

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Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway

21 January 2018

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An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

21 January 2018

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Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts

21 January 2018

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Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint.

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M408026200

ATR and ATM regulate the timing of DNA replication origin firing

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M408026200

Uninterrupted MCM2-7 function required for DNA replication fork progression

21 January 2018

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Paradoxes of eukaryotic DNA replication: MCM proteins and the random completion problem.

21 January 2018

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A rotary pumping model for helicase function of MCM proteins at a distance from replication forks.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408026200

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2 September 2017

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