Relief of p53-mediated telomerase suppression by p73. (Q38330053)

2 September 2017

title

Relief of p53-mediated telomerase suppression by p73. (English)

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2 September 2017

Wen Hong Toh

1

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2 September 2017

Satoru Kyo

series ordinal

2

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2 September 2017

Kanaga Sabapathy

series ordinal

3

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2 September 2017

language of work or name

English

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publication date

25 February 2005

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

280

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2 September 2017

issue

17

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2 September 2017

page(s)

17329-17338

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Telomerase in the human organism

2 September 2017

cites work

1 reference

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Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis

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Antisense hTERT inhibits thyroid cancer cell growth

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Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy

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Inhibition of telomerase activity with hTERT antisense increases the effect of CDDP-induced apoptosis in myeloid leukemia

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Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

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p53; from inductive signal to cellular effect

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p53-dependent down-regulation of telomerase is mediated by p21waf1.

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Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts

21 January 2018

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Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

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Functional regulation of p73 and p63: development and cancer

21 January 2018

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

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p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas

21 January 2018

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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Tumor spectrum analysis in p53-mutant mice

21 January 2018

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Regulation of mutant p53 temperature-sensitive DNA binding.

21 January 2018

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Two new p73 splice variants, gamma and delta, with different transcriptional activity.

21 January 2018

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c-Jun regulates the stability and activity of the p53 homologue, p73.

21 January 2018

1 reference

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Multiple stress signals induce p73beta accumulation

21 January 2018

1 reference

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Multiple tumor suppressor pathways negatively regulate telomerase

21 January 2018

1 reference

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

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MDM2 induces NF-kappaB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M500044200

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