Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. (Q38327788)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

title

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

author name string

Andy Y Shih

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

Vilte Barakauskas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

Heidi Erb

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

Lei Jiang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

Ping Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

Timothy H Murphy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

19 April 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 January 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

22925-22936

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Chemoprotection against cancer by induction of phase 2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Nrf2 is essential for protection against acute pulmonary injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Role of NRF2 in protection against hyperoxic lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Aging, energy, and oxidative stress in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Enhanced NAD(P)H:Quinone Reductase Activity Prevents Glutamate Toxicity Produced by Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Physiological concentrations of lactate dehydrogenases and substrate inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Preferential expression of antioxidant response element mediated gene expression in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Chemoprotection against cancer by isothiocyanates and glucosinolates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Volume transmission in the CNS and its relevance for neuropsychopharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Antioxidants and oxidants regulated signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Effects of dietary and in vitro 2(3)-t-butyl-4-hydroxy-anisole and other phenols on hepatic enzyme activities in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Environmental factors in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Parkinson's disease, pesticides and mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Controversy surrounding the existence of discrete functional classes of astrocytes in adult gray matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

Cholinergic interneuron characteristics and nicotinic properties in the striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M414635200

21 January 2018

Identifiers

DOI

10.1074/JBC.M414635200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15840590 AND SRC:MED&resulttype=core&format=json

10 January 2020

1 reference