Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice (Q38310192)

2 September 2017

title

Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice (English)

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2 September 2017

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Inmaculada García-Ruiz

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Inmaculada García-Ruiz

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author name string

Cristina Rodríguez-Juan

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2 September 2017

Teresa Díaz-Sanjuan

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2 September 2017

Pilar del Hoyo

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2 September 2017

Francisco Colina

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2 September 2017

Teresa Muñoz-Yagüe

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2 September 2017

José A Solís-Herruzo

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2 September 2017

language of work or name

English

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publication date

1 September 2006

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2 September 2017

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2 September 2017

volume

44

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2 September 2017

issue

3

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2 September 2017

page(s)

581-591

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Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity

2 September 2017

cites work

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The ins and outs of mitochondrial dysfunction in NASH.

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Animal models of steatosis

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Peroxynitrite reactions and formation in mitochondria

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Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

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Nitric oxide and peroxynitrite interactions with mitochondria

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Enhancing effects of intracellular ascorbic acid on peroxynitrite-induced U937 cell death are mediated by mitochondrial events resulting in enhanced sensitivity to peroxynitrite-dependent inhibition of complex III and formation of hydrogen peroxide

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DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite

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Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue(s) in the sarcoplasmic reticulum Ca-ATPase

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Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.

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Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

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Peroxisomal fatty acid beta-oxidation in HepG2 cells

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Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

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Glutathione determination by the Tietze enzymatic recycling assay and its relationship to cellular radiation response

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Intracellular regulation of Fas-induced apoptosis in human fibroblasts by extracellular factors and cycloheximide

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Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase

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Isolation and use of liver cells

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Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction

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NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis

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7 January 2021

A reassessment of the peroxynitrite scavenging activity of uric acid

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Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study

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Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

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7 January 2021

Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice

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Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

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Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis.

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Beyond insulin resistance in NASH: TNF-alpha or adiponectin?

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The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

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Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients

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Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

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JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

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Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells

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7 January 2021

Production of nitric oxide by mitochondria

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Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis.

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Peroxynitrite-Mediated Inactivation of Manganese Superoxide Dismutase Involves Nitration and Oxidation of Critical Tyrosine Residues

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7 January 2021

Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase.

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Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry

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Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND.

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7 January 2021

Identifiers

DOI

10.1002/HEP.21313

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2 September 2017

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