Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD). (Q38295848)

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scientific article published on 09 October 2015

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English	Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).	scientific article published on 09 October 2015

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scholarly article

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27 February 2020

Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD) (English)

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27 February 2020

blood–brain barrier

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based on heuristic

inferred from title

Alzheimer's disease

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based on heuristic

inferred from title

Frédéric Calon

4

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27 February 2020

Fanchon Bourasset

8

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27 February 2020

Jean-Michel Scherrmann

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Jean-Michel Scherrmann

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Tuan Minh Do

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Agnès Dodacki

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Wael Alata

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Sophie Nicolic

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Robert Farinotti

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1 January 2016

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Journal of Alzheimer's Disease

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49

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2

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287-300

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27 February 2020

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Amyloid-β efflux from the central nervous system into the plasma

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Structure and function of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Role of the blood-brain barrier in the nutrition of the central nervous system

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Blood-brain barrier permeability to leucine-enkephalin, D-alanine2-D-leucine5-enkephalin and their N-terminal amino acid (tyrosine).

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Transport of leucine-enkephalin across the blood-brain barrier in the perfused guinea pig brain

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Upregulation of RAGE at the blood-brain barrier in streptozotocin-induced diabetic mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

beta-Amyloid efflux mediated by p-glycoprotein

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Brain insulin impairs amyloid-beta(1-40) clearance from the brain.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ABC efflux transporters in brain vasculature of Alzheimer's subjects

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer's brain

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Increased hippocampal excitability in the 3xTgAD mouse model for Alzheimer's disease in vivo

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Altered cerebral vascular volumes and solute transport at the blood-brain barriers of two transgenic mouse models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Functional characterization of the brain-to-blood efflux clearance of human amyloid-beta peptide (1-40) across the rat blood-brain barrier

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

What is the dominant Abeta species in human brain tissue? A review

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Physicochemical interactions of amyloid beta-peptide with lipid bilayers

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ApoE promotes the proteolytic degradation of Abeta

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging.

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease

1 reference

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21 January 2018

Circulating neprilysin clears brain amyloid

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21 January 2018

Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease

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21 January 2018

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

1 reference

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21 January 2018

ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2

1 reference

https://api.crossref.org/works/10.3233/JAD-150350

21 January 2018

Constitutive androstane receptor upregulates Abcb1 and Abcg2 at the blood-brain barrier after CITCO activation

1 reference

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21 January 2018

Pregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier

1 reference

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21 January 2018

Regulation of major efflux transporters under inflammatory conditions at the blood-brain barrier in vitro

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21 January 2018

Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice.

1 reference

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21 January 2018

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10.3233/JAD-150350

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26484906 AND SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26484906 AND SRC:MED&resulttype=core&format=json

27 February 2020

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