Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2 affinity of the fifth binding module of the LDL receptor. (Q38289814)

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English	Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2 affinity of the fifth binding module of the LDL receptor.	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574243 AND SRC:MED&resulttype=core&format=json

9 January 2020

Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2 affinity of the fifth binding module of the LDL receptor (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574243 AND SRC:MED&resulttype=core&format=json

9 January 2020

Adrian Velazquez-campoy

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9 January 2020

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9 January 2020

Xabier Arias-Moreno

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Xabier Arias-Moreno

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9 January 2020

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José Carlos Rodríguez

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9 January 2020

Miguel Pocoví

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23 June 2008

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9 January 2020

Journal of Biological Chemistry

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9 January 2020

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9 January 2020

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9 January 2020

22670-22679

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9 January 2020

A receptor-mediated pathway for cholesterol homeostasis

1 reference

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Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: Relation to low density lipoprotein receptor distribution

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21 January 2018

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

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Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

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Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote

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Lipoprotein receptors: new roles for ancient proteins.

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Diverse roles for the LDL receptor family

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Versatility in ligand recognition by LDL receptor family proteins: advances and frontiers

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Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity

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21 January 2018

Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol

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21 January 2018

The LDL receptor gene: a mosaic of exons shared with different proteins

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21 January 2018

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

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21 January 2018

Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module

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21 January 2018

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor

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21 January 2018

The LDL receptor: how acid pulls the trigger

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https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Structural features of the low-density lipoprotein receptor facilitating ligand binding and release

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Cooperation between fixed and low pH-inducible interfaces controls lipoprotein release by the LDL receptor

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https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1 reference

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21 January 2018

The low-density lipoprotein receptor: ligands, debates and lore

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Structure of the LDL receptor extracellular domain at endosomal pH

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Folding determinants of LDL receptor type A modules

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

Solubilization of the low density lipoprotein receptor

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

LDL-receptor mutations in Europe

1 reference

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21 January 2018

Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants

1 reference

https://api.crossref.org/works/10.1074/JBC.M802153200

21 January 2018

The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family

1 reference

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21 January 2018

Scrambled isomers as key intermediates in the oxidative folding of ligand binding module 5 of the low density lipoprotein receptor

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21 January 2018

pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1.

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Conformational stability of apoflavodoxin

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21 January 2018

Thermodynamics of BPTI folding

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Two-dimensional differential scanning calorimetry: simultaneous resolution of intrinsic protein structural energetics and ligand binding interactions by global linkage analysis

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21 January 2018

Isothermal titration calorimetric procedure to determine protein-metal ion binding parameters in the presence of excess metal ion or chelator

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21 January 2018

Protein folding in confined and crowded environments

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21 January 2018

Models for excluded volume interaction between an unfolded protein and rigid macromolecular cosolutes: macromolecular crowding and protein stability revisited.

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21 January 2018

Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor

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21 January 2018

Computational diagnosis of protein conformational diseases: short molecular dynamics simulations reveal a fast unfolding of r-LDL mutants that cause familial hypercholesterolemia.

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21 January 2018

Calcium uptake via endocytosis with rapid release from acidifying endosomes.

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Structure and physiologic function of the low-density lipoprotein receptor

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What does it mean to be natively unfolded?

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Molecular basis for LDL receptor recognition by PCSK9

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Knowing when to let go: endosomal release of LDL from the LDL-Receptor

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A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands

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10.1074/JBC.M802153200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574243 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574243 AND SRC:MED&resulttype=core&format=json

9 January 2020

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