Epigenetic changes in gastroenteropancreatic neuroendocrine tumours (Q38272919)

1 September 2017

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title

Epigenetic changes in gastroenteropancreatic neuroendocrine tumours (English)

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1 September 2017

P Mapelli

1

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author name string

E O Aboagye

series ordinal

2

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1 September 2017

J Stebbing

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3

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1 September 2017

R Sharma

series ordinal

4

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1 September 2017

language of work or name

English

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publication date

1 December 2014

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1 September 2017

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1 September 2017

volume

34

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1 September 2017

issue

34

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1 September 2017

page(s)

4439-4447

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Gastroenteropancreatic neuroendocrine tumours

1 September 2017

cites work

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DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

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Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors

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Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors).

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LINE drive. retrotransposition and genome instability

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H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of methylation-associated gene expression in neuroendocrine pancreatic tumor cells

21 January 2018

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21 January 2018

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Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists

21 January 2018

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21 January 2018

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Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.

21 January 2018

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Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells

21 January 2018

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Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells

21 January 2018

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2014.379

Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors

21 January 2018

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A Pilot Phase II Study of Valproic Acid for Treatment of Low-Grade Neuroendocrine Carcinoma

21 January 2018

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First‐line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2014.379

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21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2014.379

Hypermethylation of the IGF2 differentially methylated region 2 is a specific event in insulinomas leading to loss-of-imprinting and overexpression

31 March 2020

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Clinical implications of microsatellite instability and MLH1 gene inactivation in sporadic insulinomas

31 March 2020

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31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2014.379

DNA methyltransferases 1, 3a, and 3b overexpression and clinical significance in gastroenteropancreatic neuroendocrine tumors

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2014.379

Global DNA methylation patterns through an array-based approach in small intestinal neuroendocrine tumors

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2014.379

Global and regional CpG methylation in pheochromocytomas and abdominal paragangliomas: association to malignant behavior

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2014.379

Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2014.379

A Phase II Study of 5-AZA-2'Deoxycytidine (Decitabine) in Hormone Independent Metastatic (D2) Prostate Cancer

31 March 2020

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12 December 2020

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12 December 2020

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Identifiers

DOI

10.1038/ONC.2014.379

1 reference

Dimensions Publication ID

1 September 2017

1033591609

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1 reference