Molecular mechanisms of antibiotic resistance. (Q38272908)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

review article

1 reference

title

Molecular mechanisms of antibiotic resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

main subject

antibiotic resistance

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

Mark Webber

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

Laura Piddock

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

3

Alison J Baylay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

author name string

David O Ogbolu

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

1 December 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

Nature Reviews Microbiology

23 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

23 February 2020

issue

1

1 reference

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23 February 2020

page(s)

42-51

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25435309 AND SRC:MED&resulttype=core&format=json

Report reveals scope of US antibiotic resistance threat

23 February 2020

cites work

1 reference

High-level triclosan resistance in Pseudomonas aeruginosa is solely a result of efflux

31 March 2020

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Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase

31 March 2020

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The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens

31 March 2020

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Sensitization by heat treatment of Escherichia coli K-12 cells to hydrophobic antibacterial compounds

31 March 2020

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Transposon library screening for identification of genetic loci participating in intrinsic susceptibility and acquired resistance to antistaphylococcal agents.

31 March 2020

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Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code

31 March 2020

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In vitro synergy testing of novel antimicrobial combination therapies against Neisseria gonorrhoeae

31 March 2020

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In vitro activity of telavancin in combination with colistin versus Gram-negative bacterial pathogens

31 March 2020

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In vitro activity of doripenem in combination with various antimicrobials against multidrug-resistant Acinetobacter baumannii: possible options for the treatment of complicated infection

31 March 2020

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Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.

31 March 2020

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Multidrug resistance in bacteria

31 March 2020

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Molecular mechanisms of antibiotic resistance

31 March 2020

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Permeation rates of penicillins indicate that Escherichia coli porins function principally as nonspecific channels

31 March 2020

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Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations.

31 March 2020

1 reference

The translocation kinetics of antibiotics through porin OmpC: insights from structure-based solvation mapping using WaterMap

31 March 2020

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On the mechanism of solute uptake in Pseudomonas

31 March 2020

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Underlying mechanisms of carbapenem resistance in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli isolates at a tertiary care centre in Lebanon: role of OXA-48 and NDM-1 carbapenemases

31 March 2020

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An adaptive response of Enterobacter aerogenes to imipenem: regulation of porin balance in clinical isolates

31 March 2020

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Outbreak caused by an ertapenem-resistant, CTX-M-15-producing Klebsiella pneumoniae sequence type 101 clone carrying an OmpK36 porin variant

31 March 2020

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Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow.

31 March 2020

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Porin alterations present in non-carbapenemase-producing Enterobacteriaceae with high and intermediate levels of carbapenem resistance in Chile.

31 March 2020

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Spread of an OmpK36-modified ST15 Klebsiella pneumoniae variant during an outbreak involving multiple carbapenem-resistant Enterobacteriaceae species and clones

31 March 2020

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Frequent emergence of porin-deficient subpopulations with reduced carbapenem susceptibility in ESBL-producing Escherichia coli during exposure to ertapenem in an in vitro pharmacokinetic model

31 March 2020

1 reference

OmpK35 and OmpK36 porin variants associated with specific sequence types of Klebsiella pneumoniae

31 March 2020

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LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus

31 March 2020

1 reference

An inducible fusaric acid tripartite efflux pump contributes to the fusaric acid resistance in Stenotrophomonas maltophilia

31 March 2020

1 reference

The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response

31 March 2020

1 reference

Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae.

31 March 2020

1 reference

Complete sequencing of an IncHI1 plasmid encoding the carbapenemase NDM-1, the ArmA 16S RNA methylase and a resistance-nodulation-cell division/multidrug efflux pump

31 March 2020

1 reference

Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria

31 March 2020

1 reference

Structure and operation of bacterial tripartite pumps.

31 March 2020

1 reference

RND efflux pumps: structural information translated into function and inhibition mechanisms.

31 March 2020

1 reference

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

31 March 2020

1 reference

Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

31 March 2020

1 reference

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

31 March 2020

1 reference

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

31 March 2020

1 reference

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

31 March 2020

1 reference

Structure of the AcrAB–TolC multidrug efflux pump

31 March 2020

1 reference

The assembled structure of a complete tripartite bacterial multidrug efflux pump

31 March 2020

1 reference

Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump

31 March 2020

1 reference

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3.

31 March 2020

1 reference

Importance of the adaptor (membrane fusion) protein hairpin domain for the functionality of multidrug efflux pumps.

31 March 2020

1 reference

Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump

31 March 2020

1 reference

Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.

31 March 2020

1 reference

Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus

31 March 2020

1 reference

Two efflux systems expressed simultaneously in multidrug-resistant Pseudomonas aeruginosa

31 March 2020

1 reference

Dueling regulatory properties of a transcriptional activator (MtrA) and repressor (MtrR) that control efflux pump gene expression in Neisseria gonorrhoeae

31 March 2020

1 reference

RamA, a member of the AraC/XylS family, influences both virulence and efflux in Salmonella enterica serovar Typhimurium.

31 March 2020

1 reference

ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium

31 March 2020

1 reference

Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon

31 March 2020

1 reference

ramR mutations affecting fluoroquinolone susceptibility in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198.

31 March 2020

1 reference

Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium

31 March 2020

1 reference

Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene

31 March 2020

1 reference

Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate

31 March 2020

1 reference

Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter

31 March 2020

1 reference

Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin

31 March 2020

1 reference

Salmonella gene rma (ramA) and multiple-drug-resistant Salmonella enterica serovar typhimurium.

31 March 2020

1 reference

Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness

31 March 2020

1 reference

Absence of mutations in marRAB or soxRS in acrB-overexpressing fluoroquinolone-resistant clinical and veterinary isolates of Escherichia coli.

31 March 2020

1 reference

Contribution of mutation at amino acid 45 of AcrR to acrB expression and ciprofloxacin resistance in clinical and veterinary Escherichia coli isolates.

31 March 2020

1 reference

Indole induces the expression of multidrug exporter genes in Escherichia coli

31 March 2020

1 reference

Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses.

31 March 2020

1 reference

Regulation of the AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat

31 March 2020

1 reference

Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus

31 March 2020

1 reference

MpeR regulates the mtr efflux locus in Neisseria gonorrhoeae and modulates antimicrobial resistance by an iron-responsive mechanism

31 March 2020

1 reference

The expression of ABC efflux pump, Rv1217c-Rv1218c, and its association with multidrug resistance of Mycobacterium tuberculosis in China

31 March 2020

1 reference

Crystal structure of the transcriptional regulator Rv1219c ofMycobacterium tuberculosis

31 March 2020

1 reference

The crystal structure of multidrug-resistance regulator RamR with multiple drugs

31 March 2020

1 reference

Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations.

31 March 2020

1 reference

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection

31 March 2020

1 reference

Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications

31 March 2020

1 reference

High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure

31 March 2020

1 reference

A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus

31 March 2020

1 reference

Detection of staphylococcal cassette chromosome mec type XI carrying highly divergent mecA, mecI, mecR1, blaZ, and ccr genes in human clinical isolates of clonal complex 130 methicillin-resistant Staphylococcus aureus

31 March 2020

1 reference

Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study

31 March 2020

1 reference

Staphylococcal cassette chromosome mec: recent advances and new insights

31 March 2020

1 reference

Rapid detection, differentiation and typing of methicillin-resistant Staphylococcus aureus harbouring either mecA or the new mecA homologue mecALGA251

31 March 2020

1 reference

Use of Vitek 2 antimicrobial susceptibility profile to identify mecC in methicillin-resistant Staphylococcus aureus

31 March 2020

1 reference

Phenotypic detection of mecC-MRSA: cefoxitin is more reliable than oxacillin

31 March 2020

1 reference

The Cfr rRNA methyltransferase confers resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A antibiotics

31 March 2020

1 reference

Presence and dissemination of the multiresistance gene cfr in Gram-positive and Gram-negative bacteria

31 March 2020

1 reference

Characterization of the IncA/C plasmid pSCEC2 from Escherichia coli of swine origin that harbours the multiresistance gene cfr

31 March 2020

1 reference

Detection of methyltransferases conferring high-level resistance to aminoglycosides in enterobacteriaceae from Europe, North America, and Latin America

31 March 2020

1 reference

Association of the novel aminoglycoside resistance determinant RmtF with NDM carbapenemase in Enterobacteriaceae isolated in India and the UK.

31 March 2020

1 reference

Structure of QnrB1, a Plasmid-mediated Fluoroquinolone Resistance Factor

31 March 2020

1 reference

Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies

31 March 2020

1 reference

Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing

31 March 2020

1 reference

Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system

31 March 2020

1 reference

Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system.

31 March 2020

1 reference

Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS

31 March 2020

1 reference

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

31 March 2020

1 reference

In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator.

31 March 2020

1 reference

MgrB inactivation is a common mechanism of colistin resistance in KPC-producing Klebsiella pneumoniae of clinical origin

31 March 2020

1 reference

Emergence of daptomycin resistance in daptomycin-naïve rabbits with methicillin-resistant Staphylococcus aureus prosthetic joint infection is associated with resistance to host defense cationic peptides and mprF polymorphisms

31 March 2020

1 reference

Biochemical characterization of cardiolipin synthase mutations associated with daptomycin resistance in enterococci

31 March 2020

1 reference

Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance

31 March 2020

1 reference

Whole-genome analyses of Enterococcus faecium isolates with diverse daptomycin MICs

31 March 2020

1 reference

Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids

31 March 2020

1 reference

Defining an extended-spectrum beta-lactamase

31 March 2020

1 reference

The emerging NDM carbapenemases

31 March 2020

1 reference

Carbapenemase-producing Enterobacteriaceae: now that the storm is finally here, how will timely detection help us fight back?

31 March 2020

1 reference

Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance

31 March 2020

1 reference

Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance

31 March 2020

1 reference

Evolution of antimicrobial resistance among Enterobacteriaceae (focus on extended spectrum β-lactamases and carbapenemases).

31 March 2020

1 reference

The spread of CTX-M-type extended-spectrum beta-lactamases.

31 March 2020

1 reference

Genetic support and diversity of acquired extended-spectrum β-lactamases in Gram-negative rods

31 March 2020

1 reference

Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria

31 March 2020

1 reference

Molecular epidemiology of fluoroquinolone-resistant ST131 Escherichia coli producing CTX-M extended-spectrum beta-lactamases in nursing homes in Belfast, UK.

31 March 2020

1 reference

Complete sequence and molecular epidemiology of IncK epidemic plasmid encoding blaCTX-M-14.

31 March 2020

1 reference

Persistence of transferable extended-spectrum-β-lactamase resistance in the absence of antibiotic pressure

31 March 2020

1 reference

Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

31 March 2020

1 reference

Carbapenemases: the versatile beta-lactamases

31 March 2020

1 reference

Hydrolysis and inhibition profiles of beta-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem

31 March 2020

1 reference

Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions

31 March 2020

1 reference

Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae

31 March 2020

1 reference

Occurrence and characterization of carbapenemase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program (2000-2004).

31 March 2020

1 reference

ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China

31 March 2020

1 reference

Complete nucleotide sequence of KPC-3-encoding plasmid pKpQIL in the epidemic Klebsiella pneumoniae sequence type 258.

31 March 2020

1 reference

Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center

31 March 2020

1 reference

Arrival of Klebsiella pneumoniae producing KPC carbapenemase in the United Kingdom

31 March 2020

1 reference

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

31 March 2020

1 reference

Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of blaNDM-1 in India, Sweden, and the United Kingdom

31 March 2020

1 reference

Emergence of Klebsiella pneumoniae isolate co-producing NDM-1 with KPC-2 from India

31 March 2020

1 reference

Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study.

31 March 2020

1 reference

How to detect NDM-1 producers

31 March 2020

1 reference

New Delhi metallo-β-lactamase (NDM-1): an update.

31 March 2020

1 reference

Outbreak of NDM-1-producing Acinetobacter baumannii in France, January to May 2013.

31 March 2020

1 reference

Bacterial resistance to antibiotics: enzymatic degradation and modification

31 March 2020

1 reference

Ligand promiscuity through the eyes of the aminoglycoside N3 acetyltransferase IIa.

31 March 2020

1 reference

Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes

31 March 2020

1 reference

Identification of a novel genomic island conferring resistance to multiple aminoglycoside antibiotics in Campylobacter coli

31 March 2020

1 reference

A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria.

31 March 2020

1 reference

Novel anti-infection agents: small-molecule inhibitors of bacterial transcription factors

31 March 2020

1 reference

Antibiotic resistance is prevalent in an isolated cave microbiome

31 March 2020

1 reference

Antibiotic resistance is ancient

31 March 2020

1 reference

Human-associated extended-spectrum β-lactamase in the Antarctic

31 March 2020

1 reference

Characterization of a chromosomally encoded extended-spectrum class A beta-lactamase from Kluyvera cryocrescens

31 March 2020

1 reference

Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types

31 March 2020

1 reference

The role of the natural environment in the emergence of antibiotic resistance in gram-negative bacteria

31 March 2020

1 reference

Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms

31 March 2020

1 reference

The shared antibiotic resistome of soil bacteria and human pathogens

31 March 2020

1 reference

The antibiotic resistance "mobilome": searching for the link between environment and clinic.

31 March 2020

1 reference

An enzyme from bacteria able to destroy penicillin. 1940.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25435309

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of an acrR mutation in multidrug resistance of in vitro-selected fluoroquinolone-resistant mutants of Salmonella enterica serovar Typhimurium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25435309