Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins (Q38266425)

1 September 2017

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title

Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins (English)

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1 September 2017

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Toshiyuki Yamaji

1

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1 September 2017

Kentaro Hanada

series ordinal

2

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1 September 2017

publication date

16 December 2014

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1 September 2017

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1 September 2017

volume

16

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1 September 2017

issue

2

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1 September 2017

page(s)

101-122

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Functional implications of sterol transport by the oxysterol-binding protein gene family.

1 September 2017

cites work

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A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP

21 January 2018

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Phospholipid transfer proteins in perspective

21 January 2018

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Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

21 January 2018

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Molecular machinery for non-vesicular trafficking of ceramide

21 January 2018

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Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

21 January 2018

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Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

21 January 2018

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Non-vesicular lipid transport by lipid-transfer proteins and beyond

21 January 2018

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Lipid landscapes and pipelines in membrane homeostasis

21 January 2018

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Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity

21 January 2018

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De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs

21 January 2018

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Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids

21 January 2018

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Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols

21 January 2018

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Sphingolipid metabolites in inflammatory disease

21 January 2018

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Glycosphingolipids in engineered mice: insights into function

21 January 2018

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Physiopathological function of hematoside (GM3 ganglioside).

21 January 2018

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TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide

21 January 2018

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Conditional LoxP-flanked glucosylceramide synthase allele controlling glycosphingolipid synthesis

21 January 2018

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Generation of general and tissue-specific gene knockout mouse models

21 January 2018

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Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase

21 January 2018

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Neutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localization

21 January 2018

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The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi

21 January 2018

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21 January 2018

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Phylogeny.fr: robust phylogenetic analysis for the non-specialist

21 January 2018

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Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells

21 January 2018

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The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

21 January 2018

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Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

21 January 2018

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A Mammalian Homolog of the Yeast LCB1 Encodes a Component of Serine Palmitoyltransferase, the Enzyme Catalyzing the First Step in Sphingolipid Synthesis

21 January 2018

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Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques

21 January 2018

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Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase

21 January 2018

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Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

21 January 2018

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Localization, topology, and function of the LCB1 subunit of serine palmitoyltransferase in mammalian cells.

21 January 2018

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The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2 -sensitive csg2Delta mutant

21 January 2018

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FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane

21 January 2018

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When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis

21 January 2018

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Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells

21 January 2018

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Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors

21 January 2018

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Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

21 January 2018

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Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

21 January 2018

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LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity

21 January 2018

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The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver

21 January 2018

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Identification and characterization of a sphingolipid delta 4-desaturase family

21 January 2018

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DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine

21 January 2018

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The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis

21 January 2018

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Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

21 January 2018

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Dihydroceramide:sphinganine C-4-hydroxylation requires Des2 hydroxylase and the membrane form of cytochrome b5

21 January 2018

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Identification of a family of animal sphingomyelin synthases

21 January 2018

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Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells

21 January 2018

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Effects of brefeldin A on sphingomyelin transport and lipid synthesis in BHK21 cells

21 January 2018

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Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis.

21 January 2018

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Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells

21 January 2018

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Cog2 Null Mutant CHO Cells Show Defective Sphingomyelin Synthesis

21 January 2018

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Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER

21 January 2018

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Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis

21 January 2018

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Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis

21 January 2018

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Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression

21 January 2018

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UDP-galactose:ceramide galactosyltransferase is a class I integral membrane protein of the endoplasmic reticulum.

21 January 2018

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Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis

21 January 2018

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Drosophila glucosylceramide synthase: a negative regulator of cell death mediated by proapoptotic factors.

21 January 2018

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Identification of active site residues in glucosylceramide synthase. A nucleotide-binding catalytic motif conserved with processive beta-glycosyltransferases

21 January 2018

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Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain

21 January 2018

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Involvement of murine β-1,4-galactosyltransferase V in lactosylceramide biosynthesis.

21 January 2018

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Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development

21 January 2018

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β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5.

21 January 2018

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Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi

21 January 2018

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Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs

21 January 2018

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Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase

21 January 2018

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The cytoplasmic tail of GM3 synthase defines its subcellular localization, stability, and in vivo activity

21 January 2018

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Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids

21 January 2018

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Transmembrane BAX Inhibitor Motif Containing (TMBIM) Family Proteins Perturbs a trans-Golgi Network Enzyme, Gb3 Synthase, and Reduces Gb3 Biosynthesis

21 January 2018

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Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway

21 January 2018

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Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis

21 January 2018

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Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids

21 January 2018

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beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepat

21 January 2018

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GA2/GM2/GD2 synthase localizes to the trans-golgi network of CHO-K1 cells

21 January 2018

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Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization

21 January 2018

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Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain

21 January 2018

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The interaction between the pleckstrin homology domain of ceramide kinase and phosphatidylinositol 4,5-bisphosphate regulates the plasma membrane targeting and ceramide 1-phosphate levels

21 January 2018

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Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release

21 January 2018

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Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2

21 January 2018

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Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells

21 January 2018

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Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase

21 January 2018

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Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells

21 January 2018

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Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis

21 January 2018

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Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels

21 January 2018

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Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin

21 January 2018

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CERT mediates intermembrane transfer of various molecular species of ceramides.

21 January 2018

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Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

21 January 2018

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Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

21 January 2018

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Ceramide transfer protein deficiency compromises organelle function and leads to senescence in primary cells

21 January 2018

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Two sphingolipid transfer proteins, CERT and FAPP2: their roles in sphingolipid metabolism

21 January 2018

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Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT

21 January 2018

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Interorganelle trafficking of ceramide is regulated by phosphorylation-dependent cooperativity between the PH and START domains of CERT.

21 January 2018

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Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin

21 January 2018

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Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells

21 January 2018

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Give lipids a START: the StAR-related lipid transfer (START) domain in mammals.

21 January 2018

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Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

21 January 2018

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A novel inhibitor of ceramide trafficking from the endoplasmic reticulum to the site of sphingomyelin synthesis.

21 January 2018

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Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer

21 January 2018

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The role of the phosphoinositides at the Golgi complex

21 January 2018

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FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

21 January 2018

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Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.

21 January 2018

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Structural Basis for the Golgi Association by the Pleckstrin Homology Domain of the Ceramide Trafficking Protein (CERT)

21 January 2018

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Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity

21 January 2018

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A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP

21 January 2018

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Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum.

21 January 2018

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Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

21 January 2018

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Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein

21 January 2018

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Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes

21 January 2018

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Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

21 January 2018

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The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.

21 January 2018

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The phosphatidylinositol-transfer protein Nir2 binds phosphatidic acid and positively regulates phosphoinositide signalling

21 January 2018

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Golgi structure in three dimensions: functional insights from the normal rat kidney cell

21 January 2018

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Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions

21 January 2018

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Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein

21 January 2018

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Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα.

21 January 2018

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Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex

21 January 2018

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ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex

21 January 2018

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Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport

21 January 2018

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Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases

21 January 2018

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Phosphatidylinositol 4-kinases: old enzymes with emerging functions

21 January 2018

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Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity

21 January 2018

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Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport

21 January 2018

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Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast

21 January 2018

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Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels

21 January 2018

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Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI

21 January 2018

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Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus

21 January 2018

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Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions

21 January 2018

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Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments golgi non-compact tubular zones and inhibits intra-golgi transport

21 January 2018

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Lipid sorting in epithelial cells

21 January 2018

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Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells

21 January 2018

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Galectin-9 trafficking regulates apical-basal polarity in Madin-Darby canine kidney epithelial cells

21 January 2018

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Golgi protein FAPP2 tubulates membranes

21 January 2018

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Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain

21 January 2018

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Interaction of Fapp1 with Arf1 and PI4P at a membrane surface: an example of coincidence detection

21 January 2018

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Cloning and expression of glycolipid transfer protein from bovine and porcine brain

21 January 2018

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Structural basis for glycosphingolipid transfer specificity

21 January 2018

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Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome

21 January 2018

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Lipid-mediated endocytosis.

21 January 2018

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Metabolic pathways and intracellular trafficking of gangliosides

21 January 2018

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Ganglioside/glycosphingolipid turnover: new concepts

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Lipid rafts as a membrane-organizing principle

21 January 2018

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Molecular mechanisms of clathrin-independent endocytosis.

21 January 2018

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Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis

21 January 2018

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Shiga toxin induces tubular membrane invaginations for its uptake into cells

21 January 2018

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The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway

21 January 2018

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Lipid metabolism in Chlamydia trachomatis-infected cells: directed trafficking of Golgi-derived sphingolipids to the chlamydial inclusion

21 January 2018

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Sphingolipids and glycoproteins are differentially trafficked to the Chlamydia trachomatis inclusion

21 January 2018

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Host cell-derived sphingolipids are required for the intracellular growth of Chlamydia trachomatis

21 January 2018

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Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development

21 January 2018

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The Lipid Transfer Protein CERT Interacts with the Chlamydia Inclusion Protein IncD and Participates to ER-Chlamydia Inclusion Membrane Contact Sites

21 January 2018

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Host sphingolipid biosynthesis as a target for hepatitis C virus therapy

21 January 2018

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Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

21 January 2018

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Sphingomyelin Activates Hepatitis C Virus RNA Polymerase in a Genotype-Specific Manner

21 January 2018

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Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

21 January 2018

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Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.

21 January 2018

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

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Transbilayer movement of monohexosylsphingolipids in endoplasmic reticulum and Golgi membranes

21 January 2018

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The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

21 January 2018

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Reconstitution of glucosylceramide flip-flop across endoplasmic reticulum: implications for mechanism of glycosphingolipid biosynthesis.

21 January 2018

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Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis

21 January 2018

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Myristic acid increases the activity of dihydroceramide Δ4-desaturase 1 through its N-terminal myristoylation

21 January 2018

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Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

21 January 2018

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Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers

21 January 2018

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GM1 structure determines SV40-induced membrane invagination and infection

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/TRA.12239

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1 September 2017

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