The cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling pathway (Q38243667)

31 August 2017

title

The cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling pathway (English)

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31 August 2017

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Hong Yao

1

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31 August 2017

Xiangyang Han

series ordinal

2

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31 August 2017

Xiuzhen Han

series ordinal

3

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31 August 2017

publication date

1 December 2014

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American journal of cardiovascular drugs

31 August 2017

published in

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31 August 2017

volume

14

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31 August 2017

issue

6

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31 August 2017

page(s)

433-442

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PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

31 August 2017

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Prolongation of insulin-induced activation of mitogen-activated protein kinases ERK 1/2 and phosphatidylinositol 3-kinase by vanadyl sulfate, a protein tyrosine phosphatase inhibitor

21 January 2018

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21 January 2018

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21 January 2018

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High-glucose condition reduces cardioprotective effects of insulin against mechanical stress-induced cell injury

21 January 2018

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Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

21 January 2018

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Cardiac mTOR protects the heart against ischemia-reperfusion injury

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

21 January 2018

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Forkhead transcription factors and cardiovascular biology

21 January 2018

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Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia

21 January 2018

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FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases

21 January 2018

1 reference

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Effect of persistent activation of phosphoinositide 3-kinase on heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

17beta-estradiol reduces cardiac hypertrophy mediated through the up-regulation of PI3K/Akt and the suppression of calcineurin/NF-AT3 signaling pathways in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Myocyte apoptosis in heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin-mediated inhibition of p38 mitogen-activated protein kinase protects cardiomyocytes in severe burns.

21 January 2018

1 reference

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Effects of insulin replacement on cardiac apoptotic and survival pathways in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin resistance affects the cytoprotective effect of insulin in cardiomyocytes through an impairment of MAPK phosphatase-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinase-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Neuronal nitric oxide synthase activation is involved in insulin-mediated cardiovascular effects in the nucleus tractus solitarii of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Different signaling pathways utilized by insulin to regulate the expression of ENT2, CNT1, CNT2 nucleoside transporters in rat cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

PI3K kinase and scaffold functions in heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin improves postischemic recovery of function through PI3K in isolated working rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin signaling: a possible pathogenesis of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Cardiac insulin resistance and microRNA modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin signaling and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Autophagic predisposition in the insulin resistant diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin resistance and heart failure: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Insulin resistance: metabolic mechanisms and consequences in the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S40256-014-0089-9

10.1007/S40256-014-0089-9

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

31 August 2017

1035336830

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1 reference