Toxicology-based cancer causation analysis of CoCr-containing hip implants: a quantitative assessment of genotoxicity and tumorigenicity studies (Q38235674)

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English	Toxicology-based cancer causation analysis of CoCr-containing hip implants: a quantitative assessment of genotoxicity and tumorigenicity studies	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 August 2017

Toxicology-based cancer causation analysis of CoCr-containing hip implants: a quantitative assessment of genotoxicity and tumorigenicity studies (English)

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Europe PubMed Central

PubMed publication ID

31 August 2017

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Whitney V Christian

1

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Europe PubMed Central

PubMed publication ID

31 August 2017

Lindsay D Oliver

2

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Europe PubMed Central

PubMed publication ID

31 August 2017

Dennis J Paustenbach

3

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Europe PubMed Central

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31 August 2017

Marisa L Kreider

4

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Europe PubMed Central

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31 August 2017

Brent L Finley

5

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Europe PubMed Central

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31 August 2017

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publication date

1 September 2014

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Europe PubMed Central

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31 August 2017

Journal of Applied Toxicology

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Europe PubMed Central

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31 August 2017

34

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Europe PubMed Central

PubMed publication ID

31 August 2017

9

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Europe PubMed Central

PubMed publication ID

31 August 2017

939-967

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Europe PubMed Central

PubMed publication ID

31 August 2017

Distribution of metal released from cobalt–chromium alloy orthopaedic wear particles implanted into air pouches in mice

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

In vitro genotoxic effects of hard metal particles assessed by alkaline single cell gel and elution assays

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Effects of coal combustion products and metal compounds on sister chromatid exchange (SCE) in a macrophagelike cell line

1 reference

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21 January 2018

Evaluation of the potential genotoxicity of chromium picolinate in mammalian cells in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Metal ion levels in the blood of patients after hip resurfacing: a comparison between twenty-eight and thirty-six-millimeter-head metal-on-metal prostheses

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Cobalt enhances DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Nanoparticles can cause DNA damage across a cellular barrier

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

A comparison of the in vitro genotoxicity of tri- and hexavalent chromium

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Frequency of spontaneous tumours in Wistar rats in 2-year studies

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Biological effects of clinically relevant wear particles from metal-on-metal hip prostheses

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Consequences of exposure to peri-articular injections of micro- and nano-particulate cobalt-chromium alloy

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Characterisation of wear particles produced by metal on metal and ceramic on metal hip prostheses under standard and microseparation simulation

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Analysis of metal ion-induced DNA damage, apoptosis, and necrosis in human (Jurkat) T-cells demonstrates Ni2 and V3 are more toxic than other metals: Al3 , Be2 , Co2 , Cr3 , Cu2 , Fe3 , Mo5 , Nb5 , Zr2 .

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Wear particles from metal-on-metal total hip replacements: effects of implant design and implantation time

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comparison of in vitro with in vivo characteristics of wear particles from metal-metal hip implants

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comet assay in human biomonitoring studies: Reliability, validation, and applications

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Metal-specific differences in levels of DNA damage caused by synovial fluid recovered at revision arthroplasty

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

In vivo genotoxicity of hard metal dust: induction of micronuclei in rat type II epithelial lung cells

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Increased chromosome translocations and aneuploidy in peripheral blood lymphocytes of patients having revision arthroplasty of the hip.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Metal wear particle characterization from metal on metal total hip replacements: transmission electron microscopy study of periprosthetic tissues and isolated particles

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Chromosomal aberrations in the peripheral blood of patients with metal-on-metal hip bearings

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Chromium-induced genotoxicity and interference in human lymphoblastoid cell (TK6) repair processes

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

2008 John Charnley award: metal ion levels after metal-on-metal total hip arthroplasty: a randomized trial

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Dose-response relationships for blood cobalt concentrations and health effects: a review of the literature and application of a biokinetic model

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Molecular and immune toxicity of CoCr nanoparticles in MoM hip arthroplasty

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay).

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The production of malignant tumours by cobalt in the rat.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Carcinogenic properties of wear particles from prostheses made in cobalt-chromium alloy.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The ability of the Comet assay to discriminate between genotoxins and cytotoxins

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Safety of trivalent chromium complexes: no evidence for DNA damage in human HaCaT keratinocytes

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Chromium(III) oxide nanoparticles induced remarkable oxidative stress and apoptosis on culture cells.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Presence of corrosion products and hypersensitivity-associated reactions in periprosthetic tissue after aseptic loosening of total hip replacements with metal bearing surfaces

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Experimental studies in metal carcinogenesis. Chromium, nickel, iron, arsenic.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Polyneuropathy caused by cobalt-chromium metallosis after total hip replacement

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Hierarchies in eukaryotic genome organization: Insights from polymer theory and simulations

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Tea and human health: the dark shadows.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Inducible SOS response system of DNA repair and mutagenesis in Escherichia coli

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Oxidative DNA base damage in renal, hepatic, and pulmonary chromatin of rats after intraperitoneal injection of cobalt(II) acetate.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

A prospective study of a ceramic-on-metal bearing in total hip arthroplasty. Clinical results, metal ion levels and chromosome analysis at two years

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Physiologically based pharmacokinetic model for humans orally exposed to chromium.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Dose-dependent cytotoxicity of clinically relevant cobalt nanoparticles and ions on macrophages in vitro

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Changes in metal levels and chromosome aberrations in the peripheral blood of patients after metal-on-metal hip arthroplasty.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Patterns of risk of cancer in patients with metal-on-metal hip replacements versus other bearing surface types: a record linkage study between a prospective joint registry and general practice electronic health records in England

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The effects of calcium phosphate deposition upon corrosion of CoCr alloys and the potential for implant failure

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Intraarticular carcinogenesis bioassays of CoCrMo and TiAlV alloys in rats.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Risk of cancer with metal-on-metal hip replacements: population based study

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Cancer incidence and cause-specific mortality in patients with metal-on-metal hip replacements in Finland

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

A study of sarcogenicity associated with Co-Cr-Mo particles implanted in animal muscle.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Hip replacement: landmark surgery in modern medical history

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Malignant neoplasms associated with orthopedic implant materials in rats

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Modes of implant failure after hip resurfacing: morphological and wear analysis of 267 retrieval specimens.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Effects of chromium picolinate on glycemic control and kidney of the obese Zucker rat

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comparative studies of chromosomal aberration and mutagenicity of the trivalent and hexavalent chromium

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Induction of spindle inhibition and abnormal mitotic figures by Cr(II), Cr(III) and Cr(VI) ions

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Current problems associated with toxicity evaluation of medical device materials and future research needs

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Severe cobalt intoxication due to prosthesis wear in repeated total hip arthroplasty

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Cancer incidence in Finnish hip replacement patients from 1980 to 1995: a nationwide cohort study involving 31,651 patients

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The effect of nano- and micron-sized particles of cobalt-chromium alloy on human fibroblasts in vitro

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Genotoxic effects of particles of surgical cobalt chrome alloy on human cells of different age in vitro.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Interpreting cobalt blood concentrations in hip implant patients

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Measurement of Single Cell Refractive Index, Dry Mass, Volume, and Density Using a Transillumination Microscope

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Urinary 8-hydroxydeoxyguanosine and sister chromatid exchanges in patients with total hip replacements

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Evaluation of the Tissue Response to the Wear Products of the Hip Joint Endo-Arthroprosthesis

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Local and systemic toxicity of nanoscale debris particles in total hip arthroplasty

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comparing metabolic effects of six different commercial trivalent chromium compounds

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Quantification of metal ion induced DNA damage with single cell array based assay

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Implants for total hip arthroplasty

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comparative assessment of implantable hip devices with different bearing surfaces: systematic appraisal of evidence

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Long-term safety evaluation of a novel oxygen-coordinated niacin-bound chromium (III) complex.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Safety and toxicological evaluation of a novel niacin-bound chromium (III) complex

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Blood metal ion testing is an effectivescreening tool to identify poorly performing metal-on-metal bearingsurfaces

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Risk of cancer in first seven years after metal-on-metal hip replacement compared with other bearings and general population: linkage study between the National Joint Registry of England and Wales and hospital episode statistics

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Genotoxicity assessment of chromium(III) propionate complex in the rat model using the comet assay

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Study of oxidative damage in growing-finishing pigs with continuous excess dietary chromium picolinate intake

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Bacterial chromosome organization and segregation

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt–tungsten carbide

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Chromium and cobalt ion release following the Durom high carbon content, forged metal-on-metal surface replacement of the hip.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Metal release mechanisms in hip replacement

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

A retrospective comparative study of mortality and causes of death among patients with metal-on-metal and metal-on-polyethylene total hip prostheses in primary osteoarthritis after a long-term follow-up

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Malignant tumors at the site of total hip prosthesis. Analytic review of 46 cases

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

DNA damage and DNA repair in cultured human cells exposed to chromate

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

In vivo wear rate of the Birmingham Hip Resurfacing arthroplasty. A review of 10 retrieved components

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Malignant Fibrous Histiocytoma at the Site of an Alumina-on-Alumina-Bearing Total Hip Arthroplasty Mimicking Infected Trochanteric Bursitis

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair.

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance

1 reference

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21 January 2018

Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation

1 reference

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21 January 2018

Fatal cardiomyopathy after revision total hip replacement for fracture of a ceramic liner

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Survival of hard-on-hard bearings in total hip arthroplasty: a systematic review

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Sister chromatid exchange in patients with joint prostheses

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

The chemical form of metallic debris in tissues surrounding metal-on-metal hips with unexplained failure

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Passive and transpassive behaviour of CoCrMo in simulated biological solutions

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Cobalt as a Carcinogen

1 reference

https://api.crossref.org/works/10.1002/JAT.3039

21 January 2018

Identifiers

10.1002/JAT.3039

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

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