Transient receptor potential channel modulators as pharmacological treatments for lower urinary tract symptoms (LUTS): myth or reality? (Q38233692)

31 August 2017

title

Transient receptor potential channel modulators as pharmacological treatments for lower urinary tract symptoms (LUTS): myth or reality? (English)

1 reference

31 August 2017

Yves Deruyver

1

0 references

Thomas Voets

object named as

Thomas Voets

series ordinal

2

0 references

Dirk De Ridder

series ordinal

3

object named as

Dirk De Ridder

1 reference

31 August 2017

Wouter Everaerts

4

1 reference

31 August 2017

publication date

21 January 2015

1 reference

31 August 2017

1 reference

31 August 2017

volume

115

1 reference

31 August 2017

issue

5

1 reference

31 August 2017

page(s)

686-697

1 reference

Bladder afferent signaling: recent findings

31 August 2017

cites work

1 reference

The capsaicin receptor: a heat-activated ion channel in the pain pathway

21 January 2018

1 reference

The concept of neurogenic inflammation

21 January 2018

1 reference

Vanilloid receptor 1 expression in the rat urinary tract

21 January 2018

1 reference

Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium

21 January 2018

1 reference

Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder.

21 January 2018

1 reference

Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells.

21 January 2018

1 reference

Functional TRP and ASIC-like channels in cultured urothelial cells from the rat.

21 January 2018

1 reference

Functional transient receptor potential vanilloid 1 is expressed in human urothelial cells

21 January 2018

1 reference

Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells.

21 January 2018

1 reference

Functional characterization of transient receptor potential channels in mouse urothelial cells

21 January 2018

1 reference

Differential localizations of the transient receptor potential channels TRPV4 and TRPV1 in the mouse urinary bladder

21 January 2018

1 reference

The TRPV4 cation channel mediates stretch-evoked Ca2 influx and ATP release in primary urothelial cell cultures

21 January 2018

1 reference

Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium

21 January 2018

1 reference

Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium

21 January 2018

1 reference

Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells

21 January 2018

1 reference

Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1

21 January 2018

1 reference

Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.

21 January 2018

1 reference

The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder

21 January 2018

1 reference

Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice

21 January 2018

1 reference

Transient receptor potential vanilloid subfamily 1 is essential for the generation of noxious bladder input and bladder overactivity in cystitis

21 January 2018

1 reference

Parallel changes in bladder suburothelial vanilloid receptor TRPV1 and pan-neuronal marker PGP9.5 immunoreactivity in patients with neurogenic detrusor overactivity after intravesical resiniferatoxin treatment

21 January 2018

1 reference

Cyclophosphamide cystitis in rats: involvement of capsaicin-sensitive primary afferents

21 January 2018

1 reference

On the origin of bladder sensing: Tr(i)ps in urology

21 January 2018

1 reference

Mechanisms underlying the recovery of urinary bladder function following spinal cord injury

21 January 2018

1 reference

Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks

21 January 2018

1 reference

The effects of capsaicin on the neurogenic hyperreflexic detrusor. A double blind placebo controlled study in patients with spinal cord disease. Preliminary results

21 January 2018

1 reference

Intravesical capsaicin in patients with detrusor hyper-reflexia--a placebo-controlled cross-over study.

21 January 2018

1 reference

Urodynamic effect of intravesical resiniferatoxin in patients with neurogenic detrusor overactivity of spinal origin: results of a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

Intravesical capsaicin versus resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients: a double-blind, randomized, controlled study

21 January 2018

1 reference

Intravesical instillation of capsaicin in urology: A review of the literature

21 January 2018

1 reference

Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial.

21 January 2018

1 reference

Effects of combination treatment of intravesical resiniferatoxin instillation and hydrodistention in patients with refractory painful bladder syndrome/interstitial cystitis: a pilot study

21 January 2018

1 reference

Intravesical resiniferatoxin for the treatment of women with idiopathic detrusor overactivity and urgency incontinence: A single dose, 4 weeks, double-blind, randomized, placebo controlled trial

21 January 2018

1 reference

Bladder sensory desensitization decreases urinary urgency.

21 January 2018

1 reference

GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models

21 January 2018

1 reference

Rat detrusor overactivity induced by chronic spinalization can be abolished by a transient receptor potential vanilloid 1 (TRPV1) antagonist

21 January 2018

1 reference

JTS-653 blocks afferent nerve firing and attenuates bladder overactivity without affecting normal voiding function

21 January 2018

1 reference

Selective pharmacological blockade of the TRPV1 receptor suppresses sensory reflexes of the rodent bladder.

21 January 2018

1 reference

Transient receptor potential channels as therapeutic targets

21 January 2018

1 reference

An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN‐D0501 in healthy subjects

21 January 2018

1 reference

Targeting TRP channels for pain relief

21 January 2018

1 reference

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

21 January 2018

1 reference

Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents

21 January 2018

1 reference

Emulsified isoflurane enhances thermal transient receptor potential vanilloid-1 channel activation-mediated sensory/nociceptive blockade by QX-314.

21 January 2018

1 reference

Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats

21 January 2018

1 reference

The vanilloid transient receptor potential channel TRPV4: from structure to disease

21 January 2018

1 reference

Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding

21 January 2018

1 reference

The mechanoreceptor TRPV4 is localized in adherence junctions of the human bladder urothelium: a morphological study.

21 January 2018

1 reference

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa

21 January 2018

1 reference

Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.

21 January 2018

1 reference

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

21 January 2018

1 reference

Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats

21 January 2018

1 reference

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

21 January 2018

1 reference

Advances in modulating thermosensory TRP channels.

21 January 2018

1 reference

The passive and active contractile properties of the neurogenic, underactive bladder.

21 January 2018

1 reference

Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2.

21 January 2018

1 reference

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

21 January 2018

1 reference

21 January 2018

1 reference

Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

21 January 2018

1 reference

Function and expression pattern of TRPM8 in bladder afferent neurons associated with bladder outlet obstruction in rats

21 January 2018

1 reference

Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract

21 January 2018

1 reference

Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8.

21 January 2018

1 reference

Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats

21 January 2018

1 reference

AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome

21 January 2018

1 reference

Bimodal action of menthol on the transient receptor potential channel TRPA1.

21 January 2018

1 reference

TRPM8-independent menthol-induced Ca2 release from endoplasmic reticulum and Golgi

21 January 2018

1 reference

Using the circumstances of symptom experience to assess the severity of urgency in the overactive bladder

21 January 2018

1 reference

Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature

21 January 2018

1 reference

21 January 2018

1 reference

Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder

21 January 2018

1 reference

Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway

21 January 2018

1 reference

Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.

21 January 2018

1 reference

TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation

21 January 2018

1 reference

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.

21 January 2018

1 reference

TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury

21 January 2018

1 reference

TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis

21 January 2018

1 reference

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJU.12876

1 reference

31 August 2017

1 reference