Research progress in signalling pathway in diabetic nephropathy (Q38217707)

31 August 2017

title

Research progress in signalling pathway in diabetic nephropathy (English)

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31 August 2017

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Wei-Jian Ni

1

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31 August 2017

Li-Qin Tang

series ordinal

2

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31 August 2017

Wei Wei

series ordinal

3

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31 August 2017

publication date

1 March 2015

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Diabetes - Metabolism: Research and Reviews

31 August 2017

published in

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31 August 2017

volume

31

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31 August 2017

issue

3

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31 August 2017

page(s)

221-233

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New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology

31 August 2017

cites work

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Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy

21 January 2018

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Diabetic nephropathy: where hemodynamics meets metabolism

21 January 2018

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Mammalian MAP kinase signalling cascades

21 January 2018

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Inhibition of MAP-kinase cascade normalizes the proliferation rate of fibroblasts from patients with Type 1 diabetes and nephropathy.

21 January 2018

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The p38 signal transduction pathway: activation and function

21 January 2018

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The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis

21 January 2018

1 reference

ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells

21 January 2018

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p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli

21 January 2018

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Differential activation of p38MAPK isoforms by MKK6 and MKK3.

21 January 2018

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Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha

21 January 2018

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Chronic inhibition of p38MAPK improves cardiac and endothelial function in experimental diabetes mellitus.

21 January 2018

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High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways.

21 January 2018

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Mitogen-activated protein kinase phosphatase-1 (MKP-1) preferentially dephosphorylates p42/44MAPK but not p38MAPK in rat pinealocytes

21 January 2018

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High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells.

21 January 2018

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P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells

21 January 2018

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Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes.

21 January 2018

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Glucose and diabetes: effects on podocyte and glomerular p38MAPK, heat shock protein 25, and actin cytoskeleton

21 January 2018

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Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy

21 January 2018

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The role of inflammatory cytokines in diabetic nephropathy.

21 January 2018

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Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes

21 January 2018

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MAP kinases in the immune response

21 January 2018

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Differential regulation and properties of MAPKs

21 January 2018

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Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases

21 January 2018

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Evaluation of JNK blockade as an early intervention treatment for type 1 diabetic nephropathy in hypertensive rats.

21 January 2018

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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

21 January 2018

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c-Jun N-terminal kinase pathways in diabetes

21 January 2018

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Both ERK/MAPK and TGF-Beta/Smad signaling pathways play a role in the kidney fibrosis of diabetic mice accelerated by blood glucose fluctuation

21 January 2018

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Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells

21 January 2018

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The mechanism of angiotensin II-induced extracellular signal-regulated kinase-1/2 activation is independent of angiotensin AT(1A) receptor internalisation.

21 January 2018

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How does angiotensin II cause renal injury?

21 January 2018

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High glucose induced VEGF expression via PKC and ERK in glomerular podocytes

21 January 2018

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Dickkopf-1 promotes hyperglycemia-induced accumulation of mesangial matrix and renal dysfunction

21 January 2018

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Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway

21 January 2018

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Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation

21 January 2018

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

21 January 2018

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TGF-beta in renal injury and disease

21 January 2018

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TGF-beta in diabetic kidney disease: role of novel signaling pathways

21 January 2018

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Transforming growth factor-β/Smad signalling in diabetic nephropathy.

21 January 2018

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TGF-β/Smad signaling in kidney disease.

21 January 2018

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Emodin attenuates high glucose-induced TGF-β1 and fibronectin expression in mesangial cells through inhibition of NF-κB pathway

21 January 2018

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Molecular mechanisms of diabetic renal hypertrophy

21 January 2018

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Smad7 as a therapeutic agent for chronic kidney diseases.

21 January 2018

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The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

21 January 2018

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Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes

21 January 2018

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Vascular endothelial growth factor induces protein synthesis in renal epithelial cells: a potential role in diabetic nephropathy

21 January 2018

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Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease

21 January 2018

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Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases

21 January 2018

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Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function

21 January 2018

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cGMP-dependent protein kinase phosphorylates and inactivates RhoA.

21 January 2018

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Acute hyperglycemia induces rapid, reversible increases in glomerular permeability in nondiabetic rats

21 January 2018

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Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure.

21 January 2018

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Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control

21 January 2018

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Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy

21 January 2018

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Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats

21 January 2018

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Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: involvement of NF-κB signaling pathway

21 January 2018

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Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

21 January 2018

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Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

21 January 2018

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High glucose induces activation of NF-κB inflammatory signaling through IκBα sumoylation in rat mesangial cells

21 January 2018

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A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage

21 January 2018

1 reference

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

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Wnt/beta-catenin signaling promotes renal interstitial fibrosis

21 January 2018

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Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetes

21 January 2018

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Sustained Wnt/β-catenin signaling rescues high glucose induction of transforming growth factor-β1-mediated renal fibrosis.

21 January 2018

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The WNT signalling pathway and diabetes mellitus

21 January 2018

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T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells

21 January 2018

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The complex world of WNT receptor signalling

21 January 2018

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Role of the JAK/STAT signaling pathway in diabetic nephropathy.

21 January 2018

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Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

21 January 2018

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Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose.

21 January 2018

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Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress

21 January 2018

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Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells.

21 January 2018

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Activation of protein kinase C isoforms and its impact on diabetic complications

21 January 2018

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PKC-alpha modulates TGF-beta signaling and impairs podocyte survival

21 January 2018

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Phosphoinositide 3-kinase is required for high glucose-induced hypertrophy and p21WAF1 expression in LLC-PK1 cells

21 January 2018

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Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice

21 January 2018

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Aldose reductase and the role of the polyol pathway in diabetic nephropathy

21 January 2018

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Glucose transporters in diabetic nephropathy

21 January 2018

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The role of reactive oxygen species in apoptosis of the diabetic kidney.

21 January 2018

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Reactive oxygen species promote caspase-12 expression and tubular apoptosis in diabetic nephropathy

21 January 2018

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Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

21 January 2018

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Rhein inhibits integrin-linked kinase expression and regulates matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio in high glucose-induced epithelial-mesenchymal transition of renal tubular cell

21 January 2018

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Expression and role of integrin-linked kinase and collagen IV in human renal allografts with interstitial fibrosis and tubular atrophy

21 January 2018

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Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria

21 January 2018

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Mechanical stress and glucose concentration modulate glucose transport in cultured rat podocytes.

21 January 2018

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Mechanical forces and TGFbeta1 reduce podocyte adhesion through alpha3beta1 integrin downregulation.

21 January 2018

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Berberine reduces fibronectin expression by suppressing the S1P-S1P2 receptor pathway in experimental diabetic nephropathy models

21 January 2018

1 reference

21 January 2018

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Diabetic nephropathy: Is it time yet for routine kidney biopsy?

21 January 2018

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7 January 2021

Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: an indicator of more advanced glomerular lesions

1 reference

7 January 2021

Glomerular and tubular induction of the transcription factor c-Jun in human renal disease

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7 January 2021

Ras modulation of superoxide activates ERK-dependent fibronectin expression in diabetes-induced renal injuries

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7 January 2021

Dopamine D1 receptor interaction with arrestin3 in neostriatal neurons.

1 reference

7 January 2021

High expression of PKC-MAPK pathway mRNAs correlates with glomerular lesions in human diabetic nephropathy

1 reference

7 January 2021

Role of vascular endothelial growth factor in diabetic nephropathy

1 reference

7 January 2021

The Renal Expression of Transforming Growth Factor- Isoforms and Their Receptors in Acute and Chronic Experimental Diabetes in Rats

1 reference

7 January 2021

A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats

1 reference

7 January 2021

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

1 reference

7 January 2021

Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.2568

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31 August 2017

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