Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer (Q38212057)

31 August 2017

title

Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer (English)

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31 August 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Julia E Wells

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

Catherine H Cole

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

Ursula R Kees

series ordinal

4

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3 June 2020

language of work or name

English

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publication date

30 May 2014

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International Journal of Cancer

31 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

volume

137

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

issue

3

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3 June 2020

page(s)

504-511

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Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

3 June 2020

cites work

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The modular architecture of a new family of growth regulators related to connective tissue growth factor

21 January 2018

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Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis

21 January 2018

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Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

21 January 2018

1 reference

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

21 January 2018

1 reference

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

21 January 2018

1 reference

All in the CCN family: essential matricellular signaling modulators emerge from the bunker

21 January 2018

1 reference

Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo

21 January 2018

1 reference

The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis

21 January 2018

1 reference

Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein

21 January 2018

1 reference

Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases.

21 January 2018

1 reference

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

21 January 2018

1 reference

CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis

21 January 2018

1 reference

Roles for CCN2 in normal physiological processes

21 January 2018

1 reference

Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7.

21 January 2018

1 reference

Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis

21 January 2018

1 reference

Connective tissue growth factor expression in pediatric myofibroblastic tumors

21 January 2018

1 reference

Suppression of cell proliferation and signaling transduction by connective tissue growth factor in non-small cell lung cancer cells

21 January 2018

1 reference

Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells

21 January 2018

1 reference

Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer

21 January 2018

1 reference

Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas

21 January 2018

1 reference

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

21 January 2018

1 reference

All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo

21 January 2018

1 reference

Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance

21 January 2018

1 reference

Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling

21 January 2018

1 reference

Connective tissue growth factor inhibits metastasis and acts as an independent prognostic marker in colorectal cancer.

21 January 2018

1 reference

Connective tissue growth factor acts as a therapeutic agent and predictor for peritoneal carcinomatosis of colorectal cancer

21 January 2018

1 reference

CTGF, intestinal stellate cells and carcinoid fibrogenesis

21 January 2018

1 reference

Prioritizing genes associated with prostate cancer development

21 January 2018

1 reference

CTGF is overexpressed in papillary thyroid carcinoma and promotes the growth of papillary thyroid cancer cells.

21 January 2018

1 reference

Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer

21 January 2018

1 reference

Connective tissue growth factor enhances the migration of gastric cancer through downregulation of E‐cadherin via the NF‐κB pathway

21 January 2018

1 reference

Connective tissue growth factor modulates oral squamous cell carcinoma invasion by activating a miR-504/FOXP1 signalling.

21 January 2018

1 reference

Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray.

21 January 2018

1 reference

miR-205 expression promotes cell proliferation and migration of human cervical cancer cells

21 January 2018

1 reference

Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade

21 January 2018

1 reference

Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis

21 January 2018

1 reference

Connective tissue growth factor immunohistochemical expression is associated with gallbladder cancer progression.

21 January 2018

1 reference

Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis

21 January 2018

1 reference

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

21 January 2018

1 reference

Identification of new genes related to the myogenic differentiation arrest of human rhabdomyosarcoma cells

21 January 2018

1 reference

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia

21 January 2018

1 reference

Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1.

21 January 2018

1 reference

High expression of connective tissue growth factor in pre-B acute lymphoblastic leukaemia

21 January 2018

1 reference

Connective tissue growth factor is an indicator of bone involvement in multiple myeloma, but matrix metalloproteinase-9 is not.

21 January 2018

1 reference

CTGF (IGFBP-rP2) is specifically expressed in malignant lymphoblasts of patients with acute lymphoblastic leukaemia (ALL).

21 January 2018

1 reference

Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.

21 January 2018

1 reference

Desmoplastic reaction influences pancreatic cancer growth behavior

21 January 2018

1 reference

Expression of connective tissue growth factor in tumor tissues is an independent predictor of poor prognosis in patients with gastric cancer

21 January 2018

1 reference

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration.

21 January 2018

1 reference

Expression and prognostic significance of THBS1, Cyr61 and CTGF in esophageal squamous cell carcinoma

21 January 2018

1 reference

The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

21 January 2018

1 reference

Expression profiling of Wilms tumors reveals new candidate genes for different clinical parameters

21 January 2018

1 reference

Expression of connective tissue growth factor is a prognostic marker for patients with intrahepatic cholangiocarcinoma

21 January 2018

1 reference

Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion

21 January 2018

1 reference

Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor

21 January 2018

1 reference

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Connective tissue growth factor expression in endocrine tumors is associated with high stromal expression of alpha-smooth muscle actin.

21 January 2018

1 reference

Cancer and the tumor microenvironment: a review of an essential relationship

21 January 2018

1 reference

Friends or foes - bipolar effects of the tumour stroma in cancer

21 January 2018

1 reference

Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth

21 January 2018

1 reference

CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway

21 January 2018

1 reference

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

21 January 2018

1 reference

Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer

21 January 2018

1 reference

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.

21 January 2018

1 reference

Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line

21 January 2018

1 reference

Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme

21 January 2018

1 reference

Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion

21 January 2018

1 reference

Connective tissue growth factor is a positive regulator of epithelial-mesenchymal transition and promotes the adhesion with gastric cancer cells in human peritoneal mesothelial cells

21 January 2018

1 reference

Tumour-cell invasion and migration: diversity and escape mechanisms

21 January 2018

1 reference

Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines

21 January 2018

1 reference

Molecular determinants of human uveal melanoma invasion and metastasis.

21 January 2018

1 reference

Connective tissue growth factor activates pluripotency genes and mesenchymal-epithelial transition in head and neck cancer cells.

21 January 2018

1 reference

CTGF inhibits cell motility and COX-2 expression in oral cancer cells

21 January 2018

1 reference

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

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Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

21 January 2018

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CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation

21 January 2018

1 reference

Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24832082 AND SRC:MED&resulttype=core&format=json

3 June 2020

1 reference