Nonviral gene delivery with dendritic self-assembling architectures (Q38211725)

31 August 2017

title

Nonviral gene delivery with dendritic self-assembling architectures (English)

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31 August 2017

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3

Rainer Haag

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31 August 2017

Ariane Tschiche

1

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31 August 2017

Shashwat Malhotra

series ordinal

2

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31 August 2017

publication date

1 April 2014

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31 August 2017

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31 August 2017

volume

9

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31 August 2017

issue

5

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31 August 2017

page(s)

667-693

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Recent developments in the use of adenoviruses and immunotoxins in cancer gene therapy.

31 August 2017

cites work

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

21 January 2018

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Functional lipids and lipoplexes for improved gene delivery.

21 January 2018

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Materials for Non-Viral Gene Delivery

21 January 2018

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Non-viral gene therapy: polycation-mediated DNA delivery

21 January 2018

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Polymers for gene delivery across length scales.

21 January 2018

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Post-transcriptional gene silencing by siRNAs and miRNAs

21 January 2018

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Gene therapy - promises, problems and prospects

21 January 2018

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Electroporation for targeted gene transfer

21 January 2018

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Microbubble-enhanced ultrasound for vascular gene delivery

21 January 2018

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Physical methods for gene transfer: improving the kinetics of gene delivery into cells

21 January 2018

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Synthetic DNA delivery systems

21 January 2018

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Design and development of polymers for gene delivery

21 January 2018

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Nonviral vectors for gene delivery

21 January 2018

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Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery

21 January 2018

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New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells

21 January 2018

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Self-assembling nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers

21 January 2018

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DNA condensation by multivalent cations

21 January 2018

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Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

21 January 2018

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Formation and intracellular trafficking of lipoplexes and polyplexes

21 January 2018

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Intracellular trafficking of nonviral vectors

21 January 2018

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Potocytosis and cellular exit of complexes as cellular pathways for gene delivery by polycations

21 January 2018

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Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity?

21 January 2018

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Polycationic beta-cyclodextrin "click clusters": monodisperse and versatile scaffolds for nucleic acid delivery

21 January 2018

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Barriers to nonviral gene delivery

21 January 2018

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Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms

21 January 2018

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Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

21 January 2018

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Chitosans for gene delivery

21 January 2018

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Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses.

21 January 2018

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In vivo gene delivery by nonviral vectors: overcoming hurdles?

21 January 2018

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Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

21 January 2018

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Efficient and targeted delivery of siRNA in vivo

21 January 2018

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Knocking down barriers: advances in siRNA delivery

21 January 2018

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Non-viral gene delivery systems

21 January 2018

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Peptide vectors for the nonviral delivery of nucleic acids

21 January 2018

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Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

21 January 2018

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Lipid-based nanoparticles for nucleic acid delivery

21 January 2018

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The headgroup evolution of cationic lipids for gene delivery

21 January 2018

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Structure-activity relationship in cationic lipid mediated gene transfection.

21 January 2018

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Lipophosphoramidates as lipidic part of lipospermines for gene delivery.

21 January 2018

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

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Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

21 January 2018

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In vitro gene delivery by degraded polyamidoamine dendrimers

21 January 2018

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Dendritic polyamines: simple access to new materials with defined treelike structures for application in nonviral gene delivery

21 January 2018

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Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers

21 January 2018

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DNA complexing with polyamidoamine dendrimers: implications for transfection

21 January 2018

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Substituted beta-cyclodextrins interact with PAMAM dendrimer-DNA complexes and modify transfection efficiency

21 January 2018

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Biological applications of dendrimers

21 January 2018

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Dendrimers in biomedical applications--reflections on the field

21 January 2018

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Designing dendrimers for biological applications

21 January 2018

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Dendrimers in gene delivery

21 January 2018

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Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

21 January 2018

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Dendrimer biocompatibility and toxicity

21 January 2018

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Remnant cationic dendrimers block RNA migration in electrophoresis after monophasic lysis

21 January 2018

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Evaluating the gene-expression profiles of HeLa cancer cells treated with activated and nonactivated poly(amidoamine) dendrimers, and their DNA complexes

21 January 2018

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Biomedical applications of dendrimers: a tutorial

21 January 2018

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Efficient synthesis and cell-transfection properties of a new multivalent cationic lipid for nonviral gene delivery.

21 January 2018

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Amphiphilic Dendrimers: Novel Self‐Assembling Vectors for Efficient Gene Delivery

21 January 2018

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Synergistic effects in gene delivery-a structure-activity approach to the optimisation of hybrid dendritic-lipidic transfection agents.

21 January 2018

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Self-assembled multivalency: dynamic ligand arrays for high-affinity binding

21 January 2018

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Dendrimers and the double helix--from DNA binding towards gene therapy

21 January 2018

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Cytokines as biomarkers of nanoparticle immunotoxicity

21 January 2018

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Cationic lipids activate intracellular signaling pathways

21 January 2018

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Self-assembling dendrimers.

21 January 2018

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Polystyrene-dendrimer amphiphilic block copolymers with a generation-dependent aggregation

21 January 2018

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Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers

21 January 2018

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Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles

21 January 2018

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DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers

21 January 2018

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Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides

21 January 2018

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Versatile peptide dendrimers for nucleic acid delivery.

21 January 2018

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Dendriplexes and their characterisation

21 January 2018

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Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide.

21 January 2018

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Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity.

21 January 2018

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Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

21 January 2018

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New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery.

21 January 2018

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Dendritic cationic lipids with highly charged headgroups for efficient gene delivery

21 January 2018

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A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice.

21 January 2018

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Nanogyroids Incorporating Multivalent Lipids: Enhanced Membrane Charge Density and Pore Forming Ability for Gene Silencing

21 January 2018

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Liquid crystalline phases of dendritic lipid-DNA self-assemblies: lamellar, hexagonal, and DNA bundles

21 January 2018

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Cationic liposome-DNA complexes: from liquid crystal science to gene delivery applications

21 January 2018

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Cationic liposome-nucleic acid complexes: liquid crystal phases with applications in gene therapy

21 January 2018

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Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes

21 January 2018

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An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery

21 January 2018

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Three-Dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes

21 January 2018

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Cationic lipid-DNA complexes for gene therapy: understanding the relationship between complex structure and gene delivery pathways at the molecular level

21 January 2018

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High-affinity multivalent DNA binding by using low-molecular-weight dendrons

21 January 2018

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Dendrons with spermine surface groups as potential building blocks for nonviral vectors in gene therapy

21 January 2018

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An improved synthesis of a trifurcated newkome-type monomer and orthogonally protected two-generation dendrons

21 January 2018

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Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules.

21 January 2018

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Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

21 January 2018

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The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

21 January 2018

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Supramolecular structures from dendrons and dendrimers

21 January 2018

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Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

21 January 2018

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Polyamidoamine dendron-bearing lipid assemblies: Their morphologies and gene transfection ability

21 January 2018

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Synthesis of novel cationic lipids having polyamidoamine dendrons and their transfection activity

21 January 2018

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Glycine-terminated dendritic amphiphiles for nonviral gene delivery

21 January 2018

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A review of stimuli-responsive nanocarriers for drug and gene delivery

21 January 2018

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Acid-triggered transformation of diortho ester phosphocholine liposome

21 January 2018

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Lipophilic pyrylium salts in the synthesis of efficient pyridinium-based cationic lipids, gemini surfactants, and lipophilic oligomers for gene delivery

21 January 2018

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The problem with cationic liposome/micelle-based non-viral vector systems for gene therapy

21 January 2018

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Photoresponsive amphiphiles based on azobenzene-dendritic glycerol conjugates show switchable transport behavior

21 January 2018

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Self-assembled multivalent RGD-peptide arrays--morphological control and integrin binding

21 January 2018

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A novel anionic dendrimer for improved cellular delivery of antisense oligonucleotides.

21 January 2018

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Tripod-like cationic lipids as novel gene carriers

21 January 2018

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The use of solid supports to generate nucleic acid carriers.

21 January 2018

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Optically degradable dendrons for temporary adhesion of proteins to DNA.

21 January 2018

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Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery

21 January 2018

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Synthesis of poly(amidoamine) dendron-bearing lipids with poly(ethylene glycol) grafts and their use for stabilization of nonviral gene vectors

21 January 2018

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Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry

21 January 2018

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A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery

21 January 2018

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New perfluorinated polycationic dimerizable detergents for the formulation of monomolecular DNA nanoparticles and their in vitro transfection efficiency

21 January 2018

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Nucleic acid transfer with hemifluorinated polycationic lipids

21 January 2018

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Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies

21 January 2018

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Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery

21 January 2018

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Dendrosome-dendriplex inside liposomes: as a gene delivery system.

21 January 2018

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Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity

21 January 2018

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Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus.

21 January 2018

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Peptide dendrimer/lipid hybrid systems are efficient DNA transfection reagents: structure--activity relationships highlight the role of charge distribution across dendrimer generations

21 January 2018

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Less is more – multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery

21 January 2018

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Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

21 January 2018

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Polyglycerol-based amphiphilic dendrons as potential siRNA carriers for in vivo applications

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/NNM.14.32

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31 August 2017

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