Autophagy--a key player in cellular and body metabolism (Q38198952)

30 August 2017

title

Autophagy--a key player in cellular and body metabolism (English)

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30 August 2017

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Kook Hwan Kim

1

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30 August 2017

Myung-Shik Lee

series ordinal

2

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30 August 2017

publication date

25 March 2014

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Nature Reviews Endocrinology

30 August 2017

published in

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30 August 2017

volume

10

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30 August 2017

issue

6

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30 August 2017

page(s)

322-337

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Autophagy as a regulated pathway of cellular degradation

30 August 2017

cites work

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The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

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A ubiquitin-like system mediates protein lipidation

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Structural basis for sorting mechanism of p62 in selective autophagy

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Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

21 January 2018

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LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

21 January 2018

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

21 January 2018

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The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

21 January 2018

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Termination of autophagy and reformation of lysosomes regulated by mTOR

21 January 2018

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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Metabolite profiles and the risk of developing diabetes

21 January 2018

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Bidirectional transport of amino acids regulates mTOR and autophagy

21 January 2018

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H( )-ATPase

21 January 2018

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Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

21 January 2018

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p62 is a key regulator of nutrient sensing in the mTORC1 pathway.

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

21 January 2018

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Glutaminolysis activates Rag-mTORC1 signaling.

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Amino acid signalling upstream of mTOR

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy regulation by nutrient signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

TFEB links autophagy to lysosomal biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

AMPK: a nutrient and energy sensor that maintains energy homeostasis

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

21 January 2018

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https://api.crossref.org/works/10.1038/NRENDO.2014.35

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy regulates lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The MAP1-LC3 conjugation system is involved in lipid droplet formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Altered lipid content inhibits autophagic vesicular fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Fatty acids suppress autophagic turnover in β-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Protective role of autophagy in palmitate-induced INS-1 beta-cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A ceramide-centric view of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Ceramide starves cells to death by downregulating nutrient transporter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Methods for monitoring autophagy using GFP-LC3 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy in human type 2 diabetes pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Skeletal muscle insulin resistance is the primary defect in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy is required to maintain muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

FoxO3 controls autophagy in skeletal muscle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Cell signals influencing hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy in Myf5 progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The origins of brown adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Loss of autophagy in hypothalamic POMC neurons impairs lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The immune system as a sensor of the metabolic state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Adaptive immunity in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Inflammasome is a central player in the induction of obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Macrophage autophagy plays a protective role in advanced atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy links inflammasomes to atherosclerotic progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Suppression of autophagy in osteocytes mimics skeletal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Endocrine regulation of energy metabolism by the skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy in mammalian development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Principles and current strategies for targeting autophagy for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Developmental expression of LC3α and β: Absence of fibronectin or autophagy phenotype in LC3β knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy is essential for mouse sense of balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Genetic analysis of the ATG7 gene promoter in sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A transcriptional variant of the LC3A gene is involved in autophagy and frequently inactivated in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Potentially functional polymorphisms in ATG10 are associated with risk of breast cancer in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Role for the obesity-related FTO gene in the cellular sensing of amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

A Quantitative Trait Locus for Body Fat on Chromosome 1q43 in French Canadians: Linkage and Association Studies*

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Novel pharmacological modulators of autophagy and therapeutic prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy modulation as a potential therapeutic target for diverse diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Duration of rapamycin treatment has differential effects on metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Protective Effect of the Immunosuppressant Sirolimus Against Aortic Atherosclerosis In Apo E-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Selective clearance of macrophages in atherosclerotic plaques by autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Comparison of Everolimus-Eluting Stent With Paclitaxel-Eluting Stent in Long Chronic Total Occlusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Treatment with low dose metformin in patients with peripheral vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Exenatide as a treatment for diabetes and obesity: implications for cardiovascular risk reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other glucose-lowering therapies: a retrospective analysis of the LifeLink database

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Identification of a candidate therapeutic autophagy-inducing peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy: a targetable linchpin of cancer cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy as a crosstalk mediator of metabolic organs in regulation of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Altered autophagy in human adipose tissues in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy activity is up-regulated in adipose tissue of obese individuals and modulates proinflammatory cytokine expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Overexpression of Atg5 in mice activates autophagy and extends lifespan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Metformin action on lipid metabolism in lesions of experimental aortic atherosclerosis of rabbits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Patent watch: post-approval testing shielded from patent infringement

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRENDO.2014.35

Autophagy-lysosomal pathway is involved in lipid degradation in rat liver.

31 March 2020

1 reference

12 December 2020

Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans

1 reference

12 December 2020

Autophagy regulates adipose mass and differentiation in mice

1 reference

12 December 2020

Patent watch: extra exclusivity for new medical uses

1 reference

12 December 2020

Ammonia derived from glutaminolysis is a diffusible regulator of autophagy

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2014.35

1 reference

30 August 2017

1 reference