New surprises of suppressor of cytokine signalling in liver fibrosis (Q38193547)

30 August 2017

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title

New surprises of suppressor of cytokine signalling in liver fibrosis (English)

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30 August 2017

Chang Cheng

1

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30 August 2017

Cheng Huang

2

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30 August 2017

Tao-Tao Ma

3

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30 August 2017

Tao Xu

4

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30 August 2017

Ya-Rui Wang

5

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30 August 2017

Lei Zhang

6

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30 August 2017

Li Jun

7

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30 August 2017

language of work or name

English

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publication date

6 March 2014

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Expert Opinion on Therapeutic Targets

30 August 2017

published in

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30 August 2017

volume

18

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30 August 2017

issue

4

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30 August 2017

page(s)

415-426

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Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches

30 August 2017

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Suppressors of cytokine signalling: SOCS.

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SOCS proteins: negative regulators of cytokine signaling

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Suppressors of cytokine signaling regulate angiotensin II-activated Janus kinase-signal transducers and activators of transcription pathway in renal cells.

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Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

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MicroRNA-98 and let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in response to microbial challenge

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SOCS, inflammation, and cancer

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Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia

21 January 2018

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Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

21 January 2018

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Aberrant promoter methylation and loss of Suppressor of Cytokine Signalling-1 gene expression in the development of uterine cervical carcinogenesis

21 January 2018

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Methylation of SOCS-3 and SOCS-1 in the carcinogenesis of Barrett's adenocarcinoma

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SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

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Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis

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Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation.

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Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer

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SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

21 January 2018

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Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production.

21 January 2018

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DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats

21 January 2018

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Osteopontin delays resolution of liver fibrosis

21 January 2018

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Global analysis of DNA methylation in early-stage liver fibrosis

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling

21 January 2018

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Regulation of cytokine signaling by the SOCS and Spred family proteins

21 January 2018

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The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

21 January 2018

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Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling

21 January 2018

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GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival

21 January 2018

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Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment

21 January 2018

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Methylation determines fibroblast activation and fibrogenesis in the kidney

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

Effects of SOCS 1/3 gene silencing on the expression of C/EBPα and PPARγ during differentiation and maturation of rat preadipocytes

21 January 2018

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DNA methylation patterns of peroxisome proliferator-activated receptor gamma gene associated with liver fibrosis and inflammation in chronic hepatitis B.

21 January 2018

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The role of methyl-CpG binding protein 2 in liver fibrosis

21 January 2018

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Epigenetic regulators and histone modification

21 January 2018

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IFN-beta-induced SOCS-1 negatively regulates CD40 gene expression in macrophages and microglia

21 January 2018

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The potential of microRNAs in liver fibrosis

21 January 2018

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MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development

21 January 2018

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Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

21 January 2018

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MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1

21 January 2018

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miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling.

21 January 2018

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Epigenetic regulation of hepatic stellate cell activation

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

TGF-β in epithelial to mesenchymal transition and metastasis of liver carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

SOCS3 deficiency promotes M1 macrophage polarization and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Symbiotic formulation in experimentally induced liver fibrosis in rats: intestinal microbiota as a key point to treat liver damage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Toll‐like receptor signaling in liver regeneration, fibrosis and carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1517/14728222.2014.885953

TGF-beta, Smad3 and the process of progressive fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Smad3 as a mediator of the fibrotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

SOCS regulation of the JAK/STAT signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Role of nuclear factor kappaB in liver health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Suppressor of cytokine signaling 1 (SOCS1) limits NFkappaB signaling by decreasing p65 stability within the cell nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

Immunohistochemical distribution of activated nuclear factor kappaB and peroxisome proliferator-activated receptors in carbon tetrachloride-induced chronic liver injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.2014.885953

10.1517/14728222.2014.885953

21 January 2018

Identifiers

DOI

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30 August 2017

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