Deadenylation: enzymes, regulation, and functional implications (Q38187631)

30 August 2017

title

Deadenylation: enzymes, regulation, and functional implications (English)

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30 August 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Yong-Bin Yan

series ordinal

1

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30 August 2017

language of work or name

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12 February 2014

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Wiley interdisciplinary reviews. RNA

30 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

5 June 2020

volume

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

5 June 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

421-443

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

RNA quality control in eukaryotes

5 June 2020

cites work

1 reference

Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast

21 January 2018

1 reference

Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation

21 January 2018

1 reference

Control of poly(A) tail length

21 January 2018

1 reference

Life and death in the cytoplasm: messages from the 3' end.

21 January 2018

1 reference

Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease

21 January 2018

1 reference

Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast

21 January 2018

1 reference

To localize or not to localize: mRNA fate is in 3'UTR ends

21 January 2018

1 reference

Mechanisms of deadenylation‐dependent decay

21 January 2018

1 reference

Translational control by changes in poly(A) tail length: recycling mRNAs.

21 January 2018

1 reference

Cytoplasmic RNA: a case of the tail wagging the dog.

21 January 2018

1 reference

Poly(A)-specific ribonuclease (PARN): an allosterically regulated, processive and mRNA cap-interacting deadenylase

21 January 2018

1 reference

21 January 2018

1 reference

Nocturnin: at the crossroads of clocks and metabolism

21 January 2018

1 reference

Identification of four families of yCCR4- and Mg2 -dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

21 January 2018

1 reference

Human Ccr4-Not complexes contain variable deadenylase subunits

21 January 2018

1 reference

An unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodies

21 January 2018

1 reference

The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme

21 January 2018

1 reference

X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex

21 January 2018

1 reference

Structural basis for the antiproliferative activity of the Tob-hCaf1 complex

21 January 2018

1 reference

Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease

21 January 2018

1 reference

Structural insight into poly(A) binding and catalytic mechanism of human PARN.

21 January 2018

1 reference

Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity

21 January 2018

1 reference

Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction

21 January 2018

1 reference

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex

21 January 2018

1 reference

A role for Q/N-rich aggregation-prone regions in P-body localization.

21 January 2018

1 reference

Conformational stability and multistate unfolding of poly(A)-specific ribonuclease.

21 January 2018

1 reference

Global architecture of human poly(A)-specific ribonuclease by atomic force microscopy in liquid and dynamic light scattering

21 January 2018

1 reference

Recognition of adenosine residues by the active site of poly(A)-specific ribonuclease

21 January 2018

1 reference

Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC).

21 January 2018

1 reference

The R3H domain stabilizes poly(A)-specific ribonuclease by stabilizing the RRM domain.

21 January 2018

1 reference

PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae

21 January 2018

1 reference

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

21 January 2018

1 reference

Localization of AU-rich element-containing mRNA in cytoplasmic granules containing exosome subunits

21 January 2018

1 reference

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

21 January 2018

1 reference

Conservation of the deadenylase activity of proteins of the Caf1 family in human

21 January 2018

1 reference

Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiae

21 January 2018

1 reference

Saccharomyces cerevisiae Ngl3p is an active 3'-5' exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases.

21 January 2018

1 reference

Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover

21 January 2018

1 reference

A Deadenylase Assay by Size-Exclusion Chromatography

21 January 2018

1 reference

The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway

21 January 2018

1 reference

Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA

21 January 2018

1 reference

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway

21 January 2018

1 reference

Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal

21 January 2018

1 reference

The highways and byways of mRNA decay

21 January 2018

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Identification of the active site of poly(A)-specific ribonuclease by site-directed mutagenesis and Fe(2 )-mediated cleavage

21 January 2018

1 reference

Coordination of divalent metal ions in the active site of poly(A)-specific ribonuclease

21 January 2018

1 reference

21 January 2018

1 reference

Biochemical and biophysical characterization of the deadenylase CrCaf1 from Chlamydomonas reinhardtii

21 January 2018

1 reference

The activity and selectivity of fission yeast Pop2p are affected by a high affinity for Zn2 and Mn2 in the active site

21 January 2018

1 reference

Immediate early response of the circadian polyA ribonuclease nocturnin to two extracellular stimuli.

21 January 2018

1 reference

Identification of multiple RNA features that influence CCR4 deadenylation activity

21 January 2018

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PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria

21 January 2018

1 reference

A structural basis for processivity

21 January 2018

1 reference

Modulation of poly(A)-specific ribonuclease (PARN): current knowledge and perspectives

21 January 2018

1 reference

To polyadenylate or to deadenylate: that is the question

21 January 2018

1 reference

Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae

21 January 2018

1 reference

The Ccr4-Pop2-NOT mRNA deadenylase contributes to septin organization in Saccharomyces cerevisiae

21 January 2018

1 reference

twin, a CCR4 homolog, regulates cyclin poly(A) tail length to permit Drosophila oogenesis

21 January 2018

1 reference

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

21 January 2018

1 reference

Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage

21 January 2018

1 reference

The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts

21 January 2018

1 reference

Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker.

21 January 2018

1 reference

The Arabidopsis homologs of CCR4-associated factor 1 show mRNA deadenylation activity and play a role in plant defence responses

21 January 2018

1 reference

Arabidopsis deadenylases AtCAF1a and AtCAF1b play overlapping and distinct roles in mediating environmental stress responses.

21 January 2018

1 reference

Capsicum annuum CCR4-associated factor CaCAF1 is necessary for plant development and defence response.

21 January 2018

1 reference

Analysis of ABA hypersensitive germination2 revealed the pivotal functions of PARN in stress response in Arabidopsis

21 January 2018

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Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

21 January 2018

1 reference

Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway

21 January 2018

1 reference

Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.

21 January 2018

1 reference

MicroRNA-122 modulates the rhythmic expression profile of the circadian deadenylase Nocturnin in mouse liver

21 January 2018

1 reference

Loss of Git2 induces epithelial-mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1.

21 January 2018

1 reference

Nocturnin, a deadenylase in Xenopus laevis retina: a mechanism for posttranscriptional control of circadian-related mRNA.

21 January 2018

1 reference

Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming

21 January 2018

1 reference

Nucleophosmin deposition during mRNA 3′ end processing influences poly(A) tail length

21 January 2018

1 reference

The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN

21 January 2018

1 reference

A 54-kDa fragment of the Poly(A)-specific ribonuclease is an oligomeric, processive, and cap-interacting Poly(A)-specific 3' exonuclease

21 January 2018

1 reference

Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs

21 January 2018

1 reference

Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co-ordination of transcript deadenylation, decapping and P-body formation in Aspergillus nidulans.

21 January 2018

1 reference

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

21 January 2018

1 reference

Analysis of P-body assembly in Saccharomyces cerevisiae

21 January 2018

1 reference

A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

21 January 2018

1 reference

Cytoplasmic foci are sites of mRNA decay in human cells

21 January 2018

1 reference

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

21 January 2018

1 reference

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

21 January 2018

1 reference

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

21 January 2018

1 reference

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation

21 January 2018

1 reference

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs

21 January 2018

1 reference

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

21 January 2018

1 reference

Antiproliferative protein Tob directly regulates c-myc proto-oncogene expression through cytoplasmic polyadenylation element-binding protein CPEB.

21 January 2018

1 reference

Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase

21 January 2018

1 reference

BTG/TOB factors impact deadenylases

21 January 2018

1 reference

Positive and negative regulation of poly(A) nuclease

21 January 2018

1 reference

Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b

21 January 2018

1 reference

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets

21 January 2018

1 reference

GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation

21 January 2018

1 reference

Poly(A) binding proteins: are they all created equal?

21 January 2018

1 reference

Coordinate regulation of mRNA decay networks by GU-rich elements and CELF1

21 January 2018

1 reference

Drosophila maternal Hsp83 mRNA destabilization is directed by multiple SMAUG recognition elements in the open reading frame

21 January 2018

1 reference

Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo

21 January 2018

1 reference

Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs

21 January 2018

1 reference

CUG-BP binds to RNA substrates and recruits PARN deadenylase

21 January 2018

1 reference

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin

21 January 2018

1 reference

MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment

21 January 2018

1 reference

The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.

21 January 2018

1 reference

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

21 January 2018

1 reference

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

21 January 2018

1 reference

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

21 January 2018

1 reference

Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.

21 January 2018

1 reference

Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin

21 January 2018

1 reference

Insights into the structure of the CCR4-NOT complex by electron microscopy

21 January 2018

1 reference

The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?

21 January 2018

1 reference

Genome wide expression analysis of the CCR4-NOT complex indicates that it consists of three modules with the NOT module controlling SAGA-responsive genes

21 January 2018

1 reference

C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex

21 January 2018

1 reference

NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain

21 January 2018

1 reference

Structure and assembly of the NOT module of the human CCR4-NOT complex

21 January 2018

1 reference

Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex

21 January 2018

1 reference

The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.

21 January 2018

1 reference

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

Phosphorylation dynamics during early differentiation of human embryonic stem cells.

21 January 2018

1 reference

Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells

21 January 2018

1 reference

Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability

21 January 2018

1 reference

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

21 January 2018

1 reference

Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae

21 January 2018

1 reference

Regulating the regulators: posttranslational modifications of RNA silencing factors

21 January 2018

1 reference

Finishing touches: post-translational modification of protein factors involved in mammalian pre-mRNA 3' end formation

21 January 2018

1 reference

Modifications of Small RNAs and Their Associated Proteins

21 January 2018

1 reference

Phosphorylation of Tristetraprolin by MK2 Impairs AU-Rich Element mRNA Decay by Preventing Deadenylase Recruitment

21 January 2018

1 reference

CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4.

21 January 2018

1 reference

Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases

21 January 2018

1 reference

Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytes

21 January 2018

1 reference

RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB.

21 January 2018

1 reference

Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline

21 January 2018

1 reference

Is post-transcriptional stabilization, splicing and translation of selective mRNAs a key to the DNA damage response?

21 January 2018

1 reference

Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae

21 January 2018

1 reference

Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance

21 January 2018

1 reference

DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.

21 January 2018

1 reference

Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks

21 January 2018

1 reference

The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence

21 January 2018

1 reference

The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation

21 January 2018

1 reference

The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome

21 January 2018

1 reference

Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer

21 January 2018

1 reference

3' end mRNA processing: molecular mechanisms and implications for health and disease

21 January 2018

1 reference

Regulated deadenylation in vitro

21 January 2018

1 reference

Cell-free deadenylation assays with Drosophila embryo extracts

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WRNA.1221

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24523229 AND SRC:MED&resulttype=core&format=json

5 June 2020

1 reference