Mechanisms of white matter damage in multiple sclerosis (Q38182524)

30 August 2017

title

Mechanisms of white matter damage in multiple sclerosis (English)

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30 August 2017

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Hans Lassmann

1

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30 August 2017

publication date

28 January 2014

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30 August 2017

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30 August 2017

volume

62

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30 August 2017

issue

11

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30 August 2017

page(s)

1816-1830

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Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases.

30 August 2017

cites work

1 reference

Extensive cortical remyelination in patients with chronic multiple sclerosis.

21 January 2018

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Antigen presentation in EAE: role of microglia, macrophages and dendritic cells

21 January 2018

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Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords

21 January 2018

1 reference

Clonal expansions of CD8( ) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

21 January 2018

1 reference

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla.

21 January 2018

1 reference

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

21 January 2018

1 reference

Myelination: do astrocytes play a role?

21 January 2018

1 reference

Elevated protein carbonylation in the brain white matter and gray matter of patients with multiple sclerosis

21 January 2018

1 reference

Astrocyte senescence as a component of Alzheimer's disease

21 January 2018

1 reference

Subpial demyelination in the cerebral cortex of multiple sclerosis patients

21 January 2018

1 reference

Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.

21 January 2018

1 reference

Oligodendrocytes: biology and pathology

21 January 2018

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Demyelination versus remyelination in progressive multiple sclerosis.

21 January 2018

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Homogeneity of active demyelinating lesions in established multiple sclerosis

21 January 2018

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Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents

21 January 2018

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The astrocyte in multiple sclerosis revisited

21 January 2018

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Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

21 January 2018

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Monocyte/macrophage differentiation in early multiple sclerosis lesions

21 January 2018

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Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.

21 January 2018

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Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

21 January 2018

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Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis?

21 January 2018

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Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

21 January 2018

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Axon degeneration mechanisms: commonality amid diversity

21 January 2018

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Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis

21 January 2018

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The relevance of animal models in multiple sclerosis research

21 January 2018

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Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

21 January 2018

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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

21 January 2018

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Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis

21 January 2018

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Axonal damage in acute multiple sclerosis lesions

21 January 2018

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NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

21 January 2018

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Disease-specific molecular events in cortical multiple sclerosis lesions.

21 January 2018

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Autoreactive CD8 T cells in multiple sclerosis: a new target for therapy?

21 January 2018

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Opposing effects of HLA class I molecules in tuning autoreactive CD8 T cells in multiple sclerosis

21 January 2018

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The relation between inflammation and neurodegeneration in multiple sclerosis brains.

21 January 2018

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Identification of autoantibodies associated with myelin damage in multiple sclerosis

21 January 2018

1 reference

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

21 January 2018

1 reference

Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis

21 January 2018

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Elevated myeloperoxidase activity in white matter in multiple sclerosis.

21 January 2018

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Laquinimod suppress antigen presentation in relapsing-remitting multiple sclerosis: in-vitro high-throughput gene expression study

21 January 2018

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Transcription factor NF-kappaB and inhibitor I kappaBalpha are localized in macrophages in active multiple sclerosis lesions

21 January 2018

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Degenerative and spontaneous regenerative processes after spinal cord injury

21 January 2018

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Oxidative damage in multiple sclerosis lesions

21 January 2018

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The effect of age on the non-haemin iron in the human brain

21 January 2018

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Iron and neurodegeneration in the multiple sclerosis brain

21 January 2018

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Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation

21 January 2018

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Selective upregulation of scavenger receptors in and around demyelinating areas in multiple sclerosis

21 January 2018

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Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2.

21 January 2018

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Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.

21 January 2018

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Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

21 January 2018

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A pathogenic role for myelin-specific CD8( ) T cells in a model for multiple sclerosis

21 January 2018

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Microglia and multiple sclerosis

21 January 2018

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A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology

21 January 2018

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Neuropathology of white matter disease in Leber's hereditary optic neuropathy

21 January 2018

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Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach

21 January 2018

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Cortical demyelination and diffuse white matter injury in multiple sclerosis.

21 January 2018

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Widespread demyelination in the cerebellar cortex in multiple sclerosis.

21 January 2018

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Progressive multiple sclerosis: pathology and pathogenesis

21 January 2018

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Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

21 January 2018

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The immunopathology of multiple sclerosis: an overview

21 January 2018

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Endoplasmic reticulum stress in disorders of myelinating cells.

21 January 2018

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

21 January 2018

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Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures

21 January 2018

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Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro

21 January 2018

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Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions

21 January 2018

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Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.

21 January 2018

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Defining the clinical course of multiple sclerosis: Results of an international survey

21 January 2018

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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

21 January 2018

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A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases

21 January 2018

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Inflammatory cortical demyelination in early multiple sclerosis

21 January 2018

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Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

21 January 2018

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Mitochondrial defects in acute multiple sclerosis lesions

21 January 2018

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Mitochondrial changes within axons in multiple sclerosis

21 January 2018

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Gap junction pathology in multiple sclerosis lesions and normal-appearing white matter

21 January 2018

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Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.

21 January 2018

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Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?

21 January 2018

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Neurofascin as a novel target for autoantibody-mediated axonal injury

21 January 2018

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Aquaporin-4 astrocytopathy in Baló’s disease

21 January 2018

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A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination

21 January 2018

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Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

21 January 2018

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Fumaric Acid and its esters: an emerging treatment for multiple sclerosis

21 January 2018

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How factors secreted from astrocytes impact myelin repair

21 January 2018

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How mitochondria produce reactive oxygen species

21 January 2018

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Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system.

21 January 2018

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Oligodendrocytes enforce immune tolerance of the uninfected brain by purging the peripheral repertoire of autoreactive CD8 T cells

21 January 2018

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Astrocytes in multiple sclerosis: a product of their environment

21 January 2018

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Debris clearance by microglia: an essential link between degeneration and regeneration.

21 January 2018

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Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

21 January 2018

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Cerebral white matter is highly vulnerable to ischemia

21 January 2018

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Remyelination can be extensive in multiple sclerosis despite a long disease course

21 January 2018

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Remyelination is extensive in a subset of multiple sclerosis patients.

21 January 2018

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Microglia in neurodegenerative disease

21 January 2018

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Imaging cortical lesions in multiple sclerosis with ultra-high-field magnetic resonance imaging

21 January 2018

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Immunopathology of secondary-progressive multiple sclerosis

21 January 2018

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Multiple sclerosis. Pathology of recurrent lesions

21 January 2018

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C3-dependent mechanism of microglial priming relevant to multiple sclerosis.

21 January 2018

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Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.

21 January 2018

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Mitochondrial sirtuins--a new therapeutic target for repair and protection in multiple sclerosis

21 January 2018

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Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes.

21 January 2018

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Iron efflux from oligodendrocytes is differentially regulated in gray and white matter.

21 January 2018

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Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.

21 January 2018

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Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination.

21 January 2018

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SIRT1 activation confers neuroprotection in experimental optic neuritis

21 January 2018

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Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons.

21 January 2018

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Astrocytes: biology and pathology

21 January 2018

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Potassium channel KIR4.1 as an immune target in multiple sclerosis

21 January 2018

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Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders

21 January 2018

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Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology

21 January 2018

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Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.

21 January 2018

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Genetic inactivation of mitochondria-targeted redox enzyme p66ShcA preserves neuronal viability and mitochondrial integrity in response to oxidative challenges

21 January 2018

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Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

21 January 2018

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CCR1 /CCR5 mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis.

21 January 2018

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In vitro and in vivo models of multiple sclerosis

21 January 2018

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Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions

21 January 2018

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NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions

21 January 2018

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Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

21 January 2018

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Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.

21 January 2018

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Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.

21 January 2018

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Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination

21 January 2018

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Pathogenic implications of iron accumulation in multiple sclerosis

21 January 2018

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Astrocytes--friends or foes in multiple sclerosis?

21 January 2018

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Enhanced number and activity of mitochondria in multiple sclerosis lesions

21 January 2018

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Protective effects and mechanisms of sirtuins in the nervous system

21 January 2018

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Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis.

21 January 2018

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Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes

21 January 2018

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Anti–Myelin Oligodendrocyte Glycoprotein Antibodies in Pediatric Patients With Optic Neuritis

21 January 2018

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Expression of αB-crystallin in glia cells during lesional development in multiple sclerosis

21 January 2018

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7 January 2021

The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions

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7 January 2021

Multiple sclerosis: a quantitative and qualitative study of immunoglobulin-containing cells in the central nervous system

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7 January 2021

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

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7 January 2021

Cortical lesions in multiple sclerosis

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7 January 2021

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

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7 January 2021

Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis

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7 January 2021

The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.

1 reference

7 January 2021

[Astrocytopathy in neuromyelitis optica, multiple sclerosis and Baló's disease]

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7 January 2021

Cortical demyelination in PML and MS: Similarities and differences

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7 January 2021

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

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7 January 2021

Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets

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7 January 2021

Patterns of oligodendroglia pathology in multiple sclerosis

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7 January 2021

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

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7 January 2021

Multiple sclerosis: remyelination of nascent lesions

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7 January 2021

Myelin antigen-specific CD8 T cells are encephalitogenic and produce severe disease in C57BL/6 mice

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7 January 2021

Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?

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7 January 2021

Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis

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7 January 2021

Identifiers

DOI

10.1002/GLIA.22597

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30 August 2017

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