PAG--a multipurpose transmembrane adaptor protein. (Q38161403)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

PAG--a multipurpose transmembrane adaptor protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

main subject

transmembrane protein

0 references

author

Matouš Hrdinka

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

author name string

V Horejsi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

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publication date

11 November 2013

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29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

29 February 2020

issue

41

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29 February 2020

page(s)

4881-4892

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

Role of ITAM-containing adapter proteins and their receptors in the immune system and bone

29 February 2020

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Microdomain-dependent regulation of Lck and Fyn protein-tyrosine kinases in T lymphocyte plasma membranes

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Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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Differential effects of filipin and methyl-beta-cyclodextrin on B cell receptor signaling

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Transmembrane adaptor molecules: a new category of lymphoid-cell markers

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Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia

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Expression pattern of adaptor protein PAG: correlation between secondary lymphatic follicle and histogenetically related malignant lymphomas

21 January 2018

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Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development

21 January 2018

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Expression and purification of human PAG, a transmembrane adapter protein using an insect cell expression system and its structure basis

21 January 2018

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A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration

21 January 2018

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Separation of a cholesterol-enriched microdomain involved in T-cell signal transduction

21 January 2018

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Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones

21 January 2018

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Activation-induced endocytosis of the raft-associated transmembrane adaptor protein LAB/NTAL in B lymphocytes: evidence for a role in internalization of the B cell receptor

21 January 2018

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Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts

21 January 2018

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Csk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activation

21 January 2018

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Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2013.485

Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

21 January 2018

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Quantitative phosphoproteomics reveals SLP-76 dependent regulation of PAG and Src family kinases in T cells

21 January 2018

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Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase

21 January 2018

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Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase

21 January 2018

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Mechanism of Csk-mediated Down-regulation of Src Family Tyrosine Kinases in Epidermal Growth Factor Signaling

21 January 2018

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Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor

21 January 2018

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Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment

21 January 2018

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Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid rafts

21 January 2018

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Thy-1 associated pp85--90 is a potential docking site for SH2 domain-containing signal transduction molecules

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Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.

21 January 2018

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Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation

21 January 2018

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Regulation of FynT function by dual domain docking on PAG/Cbp

21 January 2018

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Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity.

21 January 2018

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PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes

21 January 2018

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Modulation of proximal signaling in normal and transformed B cells by transmembrane adapter Cbp/PAG.

21 January 2018

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Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts

21 January 2018

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The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src

21 January 2018

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Inhibitory Tyrosine Protein Kinase p50 Is Associated with Protein-tyrosine Phosphatase PTP-PEST in Hemopoietic and Non-hemopoietic Cells

21 January 2018

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LYP inhibits T-cell activation when dissociated from CSK.

21 January 2018

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CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2013.485

Regulation of the SRC family kinases by Csk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Removal of C-terminal SRC kinase from the immune synapse by a new binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The activation of Csk by CD4 interferes with TCR-mediated activatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Molecular regulation of T-cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The adaptor protein EBP50 is important for localization of the protein kinase A-Ezrin complex in T-cells and the immunomodulating effect of cAMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Cyclic AMP-mediated immune regulation--overview of mechanisms of action in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The ubiquitously expressed Csk adaptor protein Cbp is dispensable for embryogenesis and T-cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains Differentially Modulates Src Kinase Activity in Brain Maturation

21 January 2018

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Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling

21 January 2018

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Cutting Edge: Transmembrane phosphoprotein Csk-binding protein/phosphoprotein associated with glycosphingolipid-enriched microdomains as a negative feedback regulator of mast cell signaling through the FcepsilonRI

21 January 2018

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The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn

21 January 2018

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Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Inhibition of nephrin activation by c-mip through Csk-Cbp-Fyn axis plays a critical role in Angiotensin II-induced podocyte damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Presenilin1/γ‐secretase promotes the EphB2‐induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid‐enriched microdomains/Csk binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Proteomic identification of ZO-1/2 as a novel scaffold for Src/Csk regulatory circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Down-regulation of the Tumor Suppressor C-terminal Src Kinase (Csk)-binding Protein (Cbp)/PAG1 Is Mediated by Epigenetic Histone Modifications via the Mitogen-activated Protein Kinase (MAPK)/Phosphatidylinositol 3-Kinase (PI3K) Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The ups and downs of SRC regulation: tumor suppression by Cbp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Transforming potential of Src family kinases is limited by the cholesterol-enriched membrane microdomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The Transmembrane Adaptor Cbp/PAG1 Controls the Malignant Potential of Human Non–Small Cell Lung Cancers That Have c-Src Upregulation

21 January 2018

1 reference

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Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes

21 January 2018

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Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma.

21 January 2018

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Overexpression of Csk-binding protein contributes to renal cell carcinogenesis

21 January 2018

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Identification of the PAG1 gene as a novel target of inherent radioresistance in human laryngeal carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2013.485

Membrane-associated signaling in human B-lymphoma lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2013.485

Constitutive and Growth Factor-Regulated Phosphorylation of Caveolin-1 Occurs at the Same Site (Tyr-14) in Vivo: Identification of a c-Src/Cav-1/Grb7 Signaling Cassette

21 January 2018

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A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase

21 January 2018

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SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Association of Csk to VE-cadherin and inhibition of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Impairment in a negative regulatory system for TCR signaling in CD4 T cells from old mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Molecular alterations of the Fyn-complex occur as late events of human T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Dysregulation of Src family kinases in mast cells from epilepsy-resistant ASK versus epilepsy-prone EL mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Signal transduction in leucocytes via GPI-anchored proteins: an experimental artefact or an aspect of immunoreceptor function?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2013.485

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.485

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

1018543998

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24213579 AND SRC:MED&resulttype=core&format=json