A skin-depth analysis of integrins: role of the integrin network in health and disease. (Q38160890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

A skin-depth analysis of integrins: role of the integrin network in health and disease (English)

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29 February 2020

1

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29 February 2020

author name string

Srikala Raghavan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

29 February 2020

publication date

8 November 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

Cell Communication & Adhesion

29 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

29 February 2020

volume

20

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29 February 2020

issue

6

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29 February 2020

page(s)

155-169

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells

29 February 2020

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PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells

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The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells

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RSK2 protein suppresses integrin activation and fibronectin matrix assembly and promotes cell migration

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Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

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Use of an aggressive MCF-7 cell line variant, TMX2-28, to study cell invasion in breast cancer

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Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration

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Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

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Integrin α3 mutations with kidney, lung, and skin disease

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Induction of phenotype modifying cytokines by FERMT1 mutations.

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Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes

21 January 2018

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Integrins: bidirectional, allosteric signaling machines

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Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells.

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New roles for integrins in squamous-cell carcinoma

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CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin

21 January 2018

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A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo.

21 January 2018

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The molecular basis of filamin binding to integrins and competition with talin

21 January 2018

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Bone marrow stem cell therapy for recessive dystrophic epidermolysis bullosa.

21 January 2018

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The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

21 January 2018

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Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus

21 January 2018

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Generation and characterization of a diabody targeting the αvβ6 integrin

21 January 2018

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Clinical significance of CD151 overexpression in subtypes of invasive breast cancer

21 January 2018

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Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.

21 January 2018

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ILK, PINCH and parvin: the tIPP of integrin signalling

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Antisense integrin alphaV and beta3 gene therapy suppresses subcutaneously implanted hepatocellular carcinomas

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Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

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21 January 2018

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A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen

21 January 2018

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Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

21 January 2018

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Kindlin-3 is essential for integrin activation and platelet aggregation

21 January 2018

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Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

21 January 2018

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Impaired hair follicle morphogenesis and polarized keratinocyte movement upon conditional inactivation of integrin-linked kinase in the epidermis

21 January 2018

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Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion

21 January 2018

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α4β7 Integrin is essential for contact hypersensitivity by regulating migration of T cells to skin

21 January 2018

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Bullous pemphigoid and related subepidermal autoimmune blistering diseases

21 January 2018

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Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase.

21 January 2018

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TALEN-based gene correction for epidermolysis bullosa.

21 January 2018

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ILK expression in human basal cell carcinoma correlates with epithelial-mesenchymal transition markers and tumour invasion

21 January 2018

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Revertant mosaicism in junctional epidermolysis bullosa due to multiple correcting second-site mutations in LAMB3

21 January 2018

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Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

21 January 2018

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Small molecule antagonists of integrin receptors

21 January 2018

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Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion

21 January 2018

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Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination

21 January 2018

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SHARPIN is an endogenous inhibitor of β1-integrin activation

21 January 2018

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Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme

21 January 2018

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Interaction of endostatin with integrins implicated in angiogenesis

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Injection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa

21 January 2018

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In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa

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Kidney failure in mice lacking the tetraspanin CD151.

21 January 2018

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Transforming growth factor-β1 induces epithelial-mesenchymal transition and integrin α3β1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug.

21 January 2018

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Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells

21 January 2018

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

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A suppressive role of mitogen inducible gene-2 in mesenchymal cancer cell invasion

21 January 2018

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Ultrastructure and molecular pathogenesis of epidermolysis bullosa

21 January 2018

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Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome

21 January 2018

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Plectin deficiency results in muscular dystrophy with epidermolysis bullosa

21 January 2018

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Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation

21 January 2018

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Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

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Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma

21 January 2018

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Diminished metastasis in tetraspanin CD151–knockout mice

21 January 2018

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Supramolecular assembly of basement membranes

21 January 2018

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Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa

21 January 2018

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Keratinocytes from induced pluripotent stem cells in junctional epidermolysis bullosa

21 January 2018

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Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction

21 January 2018

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Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin

21 January 2018

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Bone marrow transplantation for recessive dystrophic epidermolysis bullosa

21 January 2018

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Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton

21 January 2018

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Role of integrins in regulating epidermal adhesion, growth and differentiation

21 January 2018

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Structural basis of integrin activation by talin

21 January 2018

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URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas

21 January 2018

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Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

21 January 2018

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Kindler surprise: mutations in a novel actin-associated protein cause Kindler syndrome.

21 January 2018

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The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

21 January 2018

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Genetic Analyses of Integrin Signaling

21 January 2018

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Dynamic regulation of the structure and functions of integrin adhesions

21 January 2018

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Characterization of mice lacking the tetraspanin superfamily member CD151

21 January 2018

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The PINCH-ILK-parvin complexes: assembly, functions and regulation.

21 January 2018

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Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice

21 January 2018

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Non-herlitz junctional epidermolysis bullosa

21 January 2018

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Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/15419061.2013.854334

Structure-Function Analysis of Tetraspanin CD151 Reveals Distinct Requirements for Tumor Cell Behaviors Mediated by α3β1 versus α6β4 Integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/15419061.2013.854334

Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/15419061.2013.854334

Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

21 January 2018

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https://api.crossref.org/works/10.3109/15419061.2013.854334

Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells

21 January 2018

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https://api.crossref.org/works/10.3109/15419061.2013.854334

Silencing of the integrin-linked kinase gene suppresses the proliferation, migration and invasion of pancreatic cancer cells (Panc-1).

21 January 2018

1 reference

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10.3109/15419061.2013.854334

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24205983 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference