Eosinophil apoptosis as a therapeutic target in allergic asthma (Q38154740)

29 August 2017

title

Eosinophil apoptosis as a therapeutic target in allergic asthma (English)

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29 August 2017

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Pinja Ilmarinen

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author name string

Hannu Kankaanranta

series ordinal

2

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29 August 2017

publication date

13 November 2013

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Basic and Clinical Pharmacology and Toxicology

29 August 2017

published in

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volume

114

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29 August 2017

issue

1

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29 August 2017

page(s)

109-117

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T-helper type 2-driven inflammation defines major subphenotypes of asthma.

29 August 2017

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Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway

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Bacterial DNA delays human eosinophil apoptosis.

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Pharmacological regulation of human eosinophil apoptosis

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Eosinophil apoptosis and clearance in asthma

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Divergent effect of mometasone on human eosinophil and neutrophil apoptosis

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CD4( )CD8( )TCR(low) thymocytes express low levels of glucocorticoid receptors while being sensitive to glucocorticoid-induced apoptosis

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Beclomethasone, budesonide and fluticasone propionate inhibit human neutrophil apoptosis

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Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

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The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils

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Nitric oxide-induced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activation.

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The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils.

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The effects of anti-asthma drugs on the phagocytic clearance of apoptotic eosinophils by A549 cells

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Involvement of annexin I in the dexamethasone-mediated upregulation of A549 cells phagocytosis of apoptotic eosinophils

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Effects of glucocorticoids on apoptosis and clearance of apoptotic cells.

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Salbutamol delays human eosinophil apoptosis via a cAMP-dependent mechanism

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Leukotriene modifiers for asthma treatment

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Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals

21 January 2018

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Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5.

21 January 2018

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Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition

21 January 2018

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21 January 2018

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Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation

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Induction of eosinophil apoptosis by the cyclin-dependent kinase inhibitor AT7519 promotes the resolution of eosinophil-dominant allergic inflammation

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IL-5-mediated eosinophil survival requires inhibition of GSK-3 and correlates with β-catenin relocalization

21 January 2018

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Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation

21 January 2018

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Sputum eosinophil apoptotic rate is positively correlated to exhaled nitric oxide in children

21 January 2018

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Modulation of nitric oxide pathways: therapeutic potential in asthma and chronic obstructive pulmonary disease

21 January 2018

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Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation.

21 January 2018

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21 January 2018

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Antieosinophilic activity of orazipone

21 January 2018

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Effects of levo- and dextrosimendan on NF-kappaB-mediated transcription, iNOS expression and NO production in response to inflammatory stimuli.

21 January 2018

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Orazipone inhibits activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 and decreases inducible nitric-oxide synthase expression and nitric oxide production in response to inf

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Adam8 limits the development of allergic airway inflammation in mice.

21 January 2018

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Selective Inducible Nitric Oxide Synthase Inhibition Has No Effect on Allergen Challenge in Asthma

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Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BCPT.12163

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29 August 2017

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