Transcriptional control of regulatory T cell development and function (Q38135555)

24016547

29 August 2017

title

Transcriptional control of regulatory T cell development and function (English)

1 reference

29 August 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Ming O Li

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

publication date

6 September 2013

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29 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

volume

34

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

issue

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

531-539

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

CCR7 and its ligands: balancing immunity and tolerance

13 June 2020

cites work

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12 December 2020

TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo

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12 December 2020

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4 CD25 regulatory cells

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12 December 2020

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3 regulatory T cells

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12 December 2020

The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4 T cells

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12 December 2020

Decrease of Foxp3 Treg cell number and acquisition of effector cell phenotype during lethal infection

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12 December 2020

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

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12 December 2020

FOXP3 controls regulatory T cell function through cooperation with NFAT

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12 December 2020

Enhanced selection of FoxP3 T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease.

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12 December 2020

Regulatory T cells: mechanisms of differentiation and function

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12 December 2020

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

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12 December 2020

Differential requirement for CARMA1 in agonist-selected T-cell development

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12 December 2020

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

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12 December 2020

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.

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12 December 2020

Inducing and expanding regulatory T cell populations by foreign antigen

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12 December 2020

c-Rel is required for the development of thymic Foxp3 CD4 regulatory T cells

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12 December 2020

An essential role for Scurfin in CD4 CD25 T regulatory cells

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12 December 2020

Oral tolerance in the absence of naturally occurring Tregs

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12 December 2020

Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.

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12 December 2020

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses

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12 December 2020

CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

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12 December 2020

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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12 December 2020

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

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12 December 2020

Transcription factor Foxp3 and its protein partners form a complex regulatory network

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12 December 2020

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

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12 December 2020

Autonomous role of medullary thymic epithelial cells in central CD4( ) T cell tolerance

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12 December 2020

An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance

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12 December 2020

Peripheral education of the immune system by colonic commensal microbiota.

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12 December 2020

Natural and adaptive foxp3 regulatory T cells: more of the same or a division of labor?

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12 December 2020

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

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12 December 2020

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

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12 December 2020

Adaptive Foxp3 regulatory T cell-dependent and -independent control of allergic inflammation

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12 December 2020

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery

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12 December 2020

Regulatory CD4( ) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

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12 December 2020

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

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12 December 2020

DNA methylation controls Foxp3 gene expression

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12 December 2020

T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

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12 December 2020

Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I

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12 December 2020

CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance

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12 December 2020

Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

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12 December 2020

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3 regulatory T cells

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12 December 2020

Selective depletion of Foxp3 regulatory T cells induces a scurfy-like disease

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12 December 2020

Eos mediates Foxp3-dependent gene silencing in CD4 regulatory T cells

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12 December 2020

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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12 December 2020

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

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12 December 2020

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

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12 December 2020

Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4 CD25 Foxp3 regulatory T cells

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12 December 2020

T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development

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12 December 2020

Regulatory T cells in the control of host-microorganism interactions (*).

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12 December 2020

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

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12 December 2020

A two-step process for thymic regulatory T cell development.

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12 December 2020

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3 regulatory T cells

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12 December 2020

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

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12 December 2020

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

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12 December 2020

Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification

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12 December 2020

Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB.

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12 December 2020

Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue

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12 December 2020

Regulatory T cells and immune tolerance

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12 December 2020

Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion

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12 December 2020

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8 T Cell Differentiation

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12 December 2020

Foxp3 interacts with c-Rel to mediate NF-κB repression

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12 December 2020

Differential requirement of PKC-theta in the development and function of natural regulatory T cells

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12 December 2020

Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature

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12 December 2020

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

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12 December 2020

Thymic selection of CD4 CD25 regulatory T cells induced by an agonist self-peptide

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12 December 2020

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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12 December 2020

Novel Foxo1-dependent transcriptional programs control T(reg) cell function

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12 December 2020

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

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12 December 2020

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

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12 December 2020

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

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12 December 2020

Identification of T helper type 1–like, Foxp3 regulatory T cells in human autoimmune disease

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12 December 2020

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

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12 December 2020

Foxo: in command of T lymphocyte homeostasis and tolerance

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12 December 2020

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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12 December 2020

T-bet( ) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

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12 December 2020

Regulatory T cell development in the absence of functional Foxp3.

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12 December 2020

Mechanisms of foxp3 T regulatory cell-mediated suppression

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12 December 2020

Foxp3-dependent programme of regulatory T-cell differentiation

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12 December 2020

Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

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12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4 CD25 immunoregulatory T cells that control autoimmune diabetes

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12 December 2020

All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

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12 December 2020

Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3 T regulatory cells

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12 December 2020

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

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12 December 2020

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

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12 December 2020

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4 T lymphocytes by CD4 CD25 regulatory T cells

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12 December 2020

Generalized multi-organ autoimmunity in CCR7-deficient mice

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12 December 2020

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

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12 December 2020

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

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12 December 2020

Differential dependence of CD4 CD25 regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

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12 December 2020

Specificity requirements for selection and effector functions of CD25 4 regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

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12 December 2020

Foxo proteins cooperatively control the differentiation of Foxp3 regulatory T cells

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12 December 2020

An inherently bifunctional subset of Foxp3 T helper cells is controlled by the transcription factor eos.

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12 December 2020

Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict

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12 December 2020

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

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12 December 2020

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

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12 December 2020

Recognition of the peripheral self by naturally arising CD25 CD4 T cell receptors

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12 December 2020

The AKT-mTOR axis regulates de novo differentiation of CD4 Foxp3 cells

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12 December 2020

Foxo transcription factors control regulatory T cell development and function

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12 December 2020

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

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12 December 2020

A function for interleukin 2 in Foxp3-expressing regulatory T cells

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12 December 2020

Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4 CD44hi Cells

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12 December 2020

Development of Foxp3( ) regulatory t cells is driven by the c-Rel enhanceosome

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12 December 2020

Nonredundant roles for Stat5a/b in directly regulating Foxp3

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12 December 2020

Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

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12 December 2020

Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

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12 December 2020

IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4 Foxp3 regulatory T cell development

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12 December 2020

Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression

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12 December 2020

IFN-γ- and IL-10-expressing virus epitope-specific Foxp3( ) T reg cells in the central nervous system during encephalomyelitis

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12 December 2020

CCR7 is required for the in vivo function of CD4 CD25 regulatory T cells

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12 December 2020

Molecular mechanisms underlying FOXP3 induction in human T cells

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12 December 2020

Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

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12 December 2020

Selective role of NFATc3 in positive selection of thymocytes

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12 December 2020

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.

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12 December 2020

Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.

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12 December 2020

Identifiers

DOI

10.1016/J.IT.2013.08.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24016547 AND SRC:MED&resulttype=core&format=json

13 June 2020

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13 June 2020

24016547

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