Replacement, refinement, and reduction: necessity of standardization and computational models for long bone fracture repair in animals. (Q38129027)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

title

Replacement, refinement, and reduction: necessity of standardization and computational models for long bone fracture repair in animals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Janin Reifenrath

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

Nina Angrisani

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

Silke Besdo

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

1 reference

30 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

Journal of Biomedical Materials Research Part A

7 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

2884-2900

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

Refining animal models in fracture research: seeking consensus in optimising both animal welfare and scientific validity for appropriate biomedical use.

7 March 2020

cites work

1 reference

In vivo models of bone repair

21 January 2018

1 reference

The biology of fracture healing

21 January 2018

1 reference

Vascular biology and the skeleton

21 January 2018

1 reference

Variability in the assessment of fracture-healing in orthopaedic trauma studies

21 January 2018

1 reference

Small animal bone healing models: standards, tips, and pitfalls results of a consensus meeting

21 January 2018

1 reference

Comparison of healing process in open osteotomy model and closed fracture model

21 January 2018

1 reference

Animal models for spinal fusion

21 January 2018

1 reference

Differences among species in compact bone tissue microstructure of mammalian skeleton: use of a discriminant function analysis for species identification

21 January 2018

1 reference

Ethical scores for animal experiments

21 January 2018

1 reference

Fish bone chemistry and ultrastructure: implications for taphonomy and stable isotope analysis

21 January 2018

1 reference

Surviving blood loss without blood transfusion in a swine poly-trauma model.

21 January 2018

1 reference

New model for simulation of fracture repair in full-grown beagle dogs: model characterization and results from a long-term study with ibandronate

21 January 2018

1 reference

Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling.

21 January 2018

1 reference

Formononetin promotes early fracture healing through stimulating angiogenesis by up-regulating VEGFR-2/Flk-1 in a rat fracture model

21 January 2018

1 reference

Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography

21 January 2018

1 reference

Effect of strontium ranelate on fracture healing in rat tibia

21 January 2018

1 reference

A single systemic dose of pamidronate improves bone mineral content and accelerates restoration of strength in a rat model of fracture repair

21 January 2018

1 reference

Estrogen and raloxifene improve metaphyseal fracture healing in the early phase of osteoporosis. A new fracture-healing model at the tibia in rat.

21 January 2018

1 reference

Expression of parathyroid hormone‐related peptide and insulin‐like growth factor I during rat fracture healing

21 January 2018

1 reference

Bone morphogenetic protein-2 coating of titanium implants increases biomechanical strength and accelerates bone remodeling in fracture treatment: a biomechanical and histological study in rats.

21 January 2018

1 reference

Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-beta1) from a biodegradable poly(D,L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats.

21 January 2018

1 reference

Fracture repair: modulation of fracture-callus and mechanical properties by sequential application of IL-6 following PTH 1-34 or PTH 28-48.

21 January 2018

1 reference

The influence of compression on the healing of experimental tibial fractures

21 January 2018

1 reference

Biodegradable composite scaffolds incorporating an intramedullary rod and delivering bone morphogenetic protein-2 for stabilization and bone regeneration in segmental long bone defects.

21 January 2018

1 reference

The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes mellitus

21 January 2018

1 reference

The effects of local platelet rich plasma delivery on diabetic fracture healing

21 January 2018

1 reference

Molecular basis for affected cartilage formation and bone union in fracture healing of the streptozotocin-induced diabetic rat.

21 January 2018

1 reference

Patterns of cytokine release and evolution of remote organs from proximal femur fracture in COPD rats

21 January 2018

1 reference

Post-junctional facilitation of Substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I.

21 January 2018

1 reference

Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I.

21 January 2018

1 reference

Effects of human amniotic fluid on fracture healing in rat tibia

21 January 2018

1 reference

1Alpha,25-dihydroxy-2beta(3-hydroxypropoxy)vitamin D3 (ED-71) suppressed callus remodeling but did not interfere with fracture healing in rat femora

21 January 2018

1 reference

Effect of 1,25-dihydroxy vitamin D3 on fracture healing and bone remodeling in ovariectomized rat femora

21 January 2018

1 reference

The effects of axial displacement on fracture callus morphology and MSC homing depend on the timing of application

21 January 2018

1 reference

Comparison of effects of alfacalcidol and alendronate on mechanical properties and bone collagen cross-links of callus in the fracture repair rat model

21 January 2018

1 reference

Locally administrated perindopril improves healing in an ovariectomized rat tibial osteotomy model

21 January 2018

1 reference

Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing

21 January 2018

1 reference

Effects of FGF-2 on metaphyseal fracture repair in rabbit tibiae

21 January 2018

1 reference

Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model

21 January 2018

1 reference

rhBMP‐2 injected in a calcium phosphate paste (α‐BSM) accelerates healing in the rabbit ulnar osteotomy model

21 January 2018

1 reference

Effects of ultrasound on osteotomy healing in a rabbit fracture model.

21 January 2018

1 reference

Early controlled passive motion improves early fracture alignment and structural properties in a closed extra-articular metacarpal fracture in a rabbit model

21 January 2018

1 reference

A first order system model of fracture healing

21 January 2018

1 reference

Action of recombinant human BMP-2 on fracture healing in rabbits is dependent on the mechanical environment

21 January 2018

1 reference

Local soft tissue compression enhances fracture healing in a rabbit fibula.

21 January 2018

1 reference

Experiment study on fracture fixation with low rigidity titanium alloy: plate fixation of tibia fracture model in rabbit

21 January 2018

1 reference

Quantitative screening of engineered implants in a long bone defect model in rabbits

21 January 2018

1 reference

Laser doppler flow imaging of open lower leg fractures in an animal experimental model

21 January 2018

1 reference

Systemic recruitment of osteoblastic cells in fracture healing.

21 January 2018

1 reference

Axial forces and bending moments in the loaded rabbit tibia in vivo.

21 January 2018

1 reference

Rabbit knee joint biomechanics: motion analysis and modeling of forces during hopping

21 January 2018

1 reference

Combination of anorganic bovine-derived hydroxyapatite with binding peptide does not enhance bone healing in a critical-size defect in a rabbit model

21 January 2018

1 reference

Evaluation of Ad-BMP-2 for enhancing fracture healing in an infected defect fracture rabbit model

21 January 2018

1 reference

Repair of an intercalated long bone defect with a synthetic biodegradable bone-inducing implant

21 January 2018

1 reference

Development of a new method in promoting fracture healing: multiple cryopreserved bone marrow injections using a rabbit model

21 January 2018

1 reference

Neuromuscular electrical stimulation enhances fracture healing: results of an animal model.

21 January 2018

1 reference

Histomorphometric evaluation of bone healing in rabbit fibular osteotomy model without fixation

21 January 2018

1 reference

Recombinant human bone morphogenetic protein 2 enhances bone healing in an experimental model of fractures at risk of non-union

21 January 2018

1 reference

Segmented interlocking nail: an in vivo evaluation of a novel humeral osteotomy fixation device in a caprine model

21 January 2018

1 reference

Unreamed or RIA reamed nailing: An experimental sheep study using comparative histological assessment of affected bone tissue in an acute fracture model

21 January 2018

1 reference

Comparison of a new braid fixation system to an interlocking intramedullary nail for tibial osteotomy repair in an ovine model

21 January 2018

1 reference

Intramedullary fixation of femoral cortical osteotomies with interlocked biodegradable self-reinforced poly-96L/4D-lactide (SR-PLA96) nails

21 January 2018

1 reference

Angle stable locking reduces interfragmentary movements and promotes healing after unreamed nailing. Study of a displaced osteotomy model in sheep tibiae

21 January 2018

1 reference

The influence of different osteosynthesis configurations with locking compression plates (LCP) on stability and fracture healing after an oblique 45° angle osteotomy

21 January 2018

1 reference

Spatial-temporal mapping of bone structural and elastic properties in a sheep model following osteotomy

21 January 2018

1 reference

Timely fracture-healing requires optimization of axial fixation stability.

21 January 2018

1 reference

Role of interfragmentary strain in fracture healing: ovine model of a healing osteotomy

21 January 2018

1 reference

The influence of cyclic compression and distraction on the healing of experimental tibial fractures

21 January 2018

1 reference

Shear movement at the fracture site delays healing in a diaphyseal fracture model

21 January 2018

1 reference

Transosseous application of low-intensity ultrasound for the enhancement and monitoring of fracture healing process in a sheep osteotomy model

21 January 2018

1 reference

Size and habit of mineral particles in bone and mineralized callus during bone healing in sheep.

21 January 2018

1 reference

Loads on muscles, tendons and bones in the hind extremities of sheep--a theoretical study.

21 January 2018

1 reference

Double-plating of ovine critical sized defects of the tibia: a low morbidity model enabling continuous in vivo monitoring of bone healing

21 January 2018

1 reference

Xenogenic transplantation of human mesenchymal stem cells in a critical size defect of the sheep tibia for bone regeneration

21 January 2018

1 reference

Comparison of the effect of reamed and unreamed locked intramedullary nailing on blood flow in the callus and strength of union following fracture of the sheep tibia.

21 January 2018

1 reference

The stress response to bilateral femoral fractures: a comparison of primary intramedullary nailing and external fixation

21 January 2018

1 reference

Computer-guided CO2-laser osteotomy of the sheep tibia: technical prerequisites and first results

21 January 2018

1 reference

CYR61 (CCN1) protein expression during fracture healing in an ovine tibial model and its relation to the mechanical fixation stability.

21 January 2018

1 reference

Mechanical induction of critically delayed bone healing in sheep: radiological and biomechanical results.

21 January 2018

1 reference

Multiscale mechanobiology of de novo bone generation, remodeling and adaptation of autograft in a common ovine femur model

21 January 2018

1 reference

Ultrasonometric evaluation of bone healing: Experimental study using a model of diaphyseal transverse osteotomy of sheep tibiae

21 January 2018

1 reference

Combined In Vivo/In Silico Study of Mechanobiological Mechanisms During Endochondral Ossification in Bone Healing

21 January 2018

1 reference

Far cortical locking can improve healing of fractures stabilized with locking plates

21 January 2018

1 reference

Increased cortical remodeling after osteotomy causes posttraumatic osteopenia.

21 January 2018

1 reference

ESB Research Award 1996. Biophysical stimuli on cells during tissue differentiation at implant interfaces

21 January 2018

1 reference

A fuzzy logic model of fracture healing.

21 January 2018

1 reference

Trabecular bone fracture healing simulation with finite element analysis and fuzzy logic

21 January 2018

1 reference

A mechano-regulation model for tissue differentiation during fracture healing: analysis of gap size and loading

21 January 2018

1 reference

Simulation of the nutrient supply in fracture healing

21 January 2018

1 reference

A numerical model of the fracture healing process that describes tissue development and revascularisation

21 January 2018

1 reference

A mechanobiological model for tissue differentiation that includes angiogenesis: a lattice-based modeling approach.

21 January 2018

1 reference

Random-walk models of cell dispersal included in mechanobiological simulations of tissue differentiation

21 January 2018

1 reference

Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing

21 January 2018

1 reference

A mechano-regulatory bone-healing model incorporating cell-phenotype specific activity

21 January 2018

1 reference

Influence of fracture gap size on the pattern of long bone healing: a computational study.

21 January 2018

1 reference

Angiogenesis in bone fracture healing: a bioregulatory model.

21 January 2018

1 reference

Simulation of fracture healing in the tibia: Mechanoregulation of cell activity using a lattice modeling approach

21 January 2018

1 reference

Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory

21 January 2018

1 reference

Mathematical modeling of fracture healing in mice: comparison between experimental data and numerical simulation results

21 January 2018

1 reference

Connecting biology and mechanics in fracture healing: an integrated mathematical modeling framework for the study of nonunions.

21 January 2018

1 reference

A finite element inverse analysis to assess functional improvement during the fracture healing process

21 January 2018

1 reference

Comparison of microCT and an inverse finite element approach for biomechanical analysis: results in a mesenchymal stem cell therapeutic system for fracture healing.

21 January 2018

1 reference

Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat.

21 January 2018

1 reference

Prediction of fracture callus mechanical properties using micro-CT images and voxel-based finite element analysis

21 January 2018

1 reference

Corroboration of mechanobiological simulations of tissue differentiation in an in vivo bone chamber using a lattice-modeling approach.

21 January 2018

1 reference

Occurrence and treatment of bone atrophic non-unions investigated by an integrative approach

21 January 2018

1 reference

Assessment of mechanobiological models for the numerical simulation of tissue differentiation around immediately loaded implants

21 January 2018

1 reference

Numerical simulation of tissue differentiation around loaded titanium implants in a bone chamber

21 January 2018

1 reference

A 3D computational simulation of fracture callus formation: influence of the stiffness of the external fixator

21 January 2018

1 reference

Corroboration of mechanoregulatory algorithms for tissue differentiation during fracture healing: Comparison with in vivo results

21 January 2018

1 reference

Bone regeneration during distraction osteogenesis: mechano-regulation by shear strain and fluid velocity

21 January 2018

1 reference

The mechanical heterogeneity of the hard callus influences local tissue strains during bone healing: a finite element study based on sheep experiments

21 January 2018

1 reference

Biomechanical model to simulate tissue differentiation and bone regeneration: application to fracture healing.

21 January 2018

1 reference

Three-dimensional simulation of fracture repair in the human tibia.

21 January 2018

1 reference

The biomechanical environment of a bone fracture and its influence upon the morphology of healing

21 January 2018

1 reference

Simulation of fracture healing incorporating mechanoregulation of tissue differentiation and dispersal/proliferation of cells

21 January 2018

1 reference

The influence of mechanical stimulus on the pattern of tissue differentiation in a long bone fracture — an FEM study

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JBM.A.34920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23946187 AND SRC:MED&resulttype=core&format=json

7 March 2020

1 reference