Redundancy and divergence in the amyloid precursor protein family (Q38109402)

29 August 2017

title

Redundancy and divergence in the amyloid precursor protein family (English)

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29 August 2017

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2

Bart De Strooper

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29 August 2017

S Ali M Shariati

1

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29 August 2017

language of work or name

English

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publication date

23 May 2013

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29 August 2017

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29 August 2017

volume

587

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29 August 2017

issue

13

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29 August 2017

page(s)

2036-2045

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Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The secretases: enzymes with therapeutic potential in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Amyloid precursor protein (APP) regulates synaptic structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Roles of the amyloid precursor protein family in the peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The origin and evolution of synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Evolutionary expansion and anatomical specialization of synapse proteome complexity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Homo- and heterodimerization of APP family members promotes intercellular adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Evolution of synapse complexity and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Biology and pathophysiology of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Gene duplication: a drive for phenotypic diversity and cause of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Structural features of the KPI domain control APP dimerization, trafficking, and processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APL-1, the Alzheimer's Amyloid precursor protein in Caenorhabditis elegans, modulates multiple metabolic pathways throughout development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Role of APP for dendritic spine formation and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APP physiological and pathophysiological functions: insights from animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APP is phosphorylated by TrkA and regulates NGF/TrkA signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Pinning down cell signaling, cancer and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

BACE (beta-secretase) modulates the processing of APLP2 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

APLP2 regulates neuronal stem cell differentiation during cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Neurogenic radial glia in the outer subventricular zone of human neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A mechanism for inside-out lamination in the neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

DISC1-binding proteins in neural development, signalling and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Pancortins interact with amyloid precursor protein and modulate cortical cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Reelin-dependent ApoER2 downregulation uncouples newborn neurons from progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Reelin sets the pace of neocortical neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Reelin signaling directly affects radial glia morphology and biochemical maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The mechanism of gamma-secretase activities through high molecular weight complex formation of presenilins is conserved in Drosophila melanogaster and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Identification of distinct gamma-secretase complexes with different APH-1 variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Functional and evolutionary insights into human brain development through global transcriptome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Accelerated recruitment of new brain development genes into the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

A high-resolution anatomical atlas of the transcriptome in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Evolution in protein interaction networks: co-evolution, rewiring and the role of duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

The amyloid-beta precursor protein: integrating structure with biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Divergence of spatial gene expression profiles following species-specific gene duplications in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

An update of DIVERGE software for functional divergence analysis of protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

Maximum-likelihood approach for gene family evolution under functional divergence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2013.05.026

10.1016/J.FEBSLET.2013.05.026

21 January 2018

Identifiers

DOI

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29 August 2017

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