Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets (Q38107451)

29 August 2017

title

Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets (English)

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29 August 2017

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Elin Hadler-Olsen

1

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29 August 2017

Jan-Olof Winberg

series ordinal

2

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29 August 2017

Lars Uhlin-Hansen

series ordinal

3

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29 August 2017

publication date

17 May 2013

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29 August 2017

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29 August 2017

volume

34

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29 August 2017

issue

4

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29 August 2017

page(s)

2041-2051

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Matrix metalloproteinases: a tail of a frog that became a prince

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Regulation of matrix metalloproteinase activity in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Structure and function of matrix metalloproteinases and TIMPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Updated biological roles for matrix metalloproteinases and new "intracellular" substrates revealed by degradomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The regulation of matrix metalloproteinases and their inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tissue inhibitors of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Understanding the role of tissue degrading enzymes and their inhibitors in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Cancer invasion and metastasis: changing views.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinases: regulators of the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

New functions for the matrix metalloproteinases in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Pericellular proteases in angiogenesis and vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinases: roles in cancer and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Emerging roles of proteases in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

A protective role for matrix metalloproteinase-3 in squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Gelatin in situ zymography on fixed, paraffin-embedded tissue: zinc and ethanol fixation preserve enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Zymographic techniques for the analysis of matrix metalloproteinases and their inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Real-time zymography and reverse zymography: a method for detecting activities of matrix metalloproteinases and their inhibitors using FITC-labeled collagen and casein as substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Plasma matrix metalloproteinase-7 as a metastatic marker and survival predictor in patients with renal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Identification of pro-MMP-7 as a serum marker for renal cell carcinoma by use of proteomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Salivary analysis of oral cancer biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinase-13 expression is associated with bone marrow microinvolvement and prognosis in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Prognostic significance of matrix metalloproteinase-1 levels in peripheral plasma and tumour tissues of lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The role of matrix metalloproteinase 2 on the survival of patients with non-small cell lung cancer: a systematic review with meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Role of serum vascular endothelial growth factor in the prediction of angiogenesis and prognosis for non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Prognostic stratification of stage IIIA pN2 non-small cell lung cancer by hierarchical clustering analysis of tissue microarray immunostaining data: an Alpe Adria Thoracic Oncology Multidisciplinary Group study (ATOM 014).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Three immunomarker support vector machines-based prognostic classifiers for stage IB non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

MMP-7 as a prognostic marker in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer - a predictor of tumour stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Serum matrix-metalloproteinase-1 is a bona fide prognostic marker for colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The clinical implications of MMP-11 and CK-20 expression in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Comparative analysis and clinical value of the expression of metalloproteases and their inhibitors by intratumor stromal fibroblasts and those at the invasive front of breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Study of matrix metalloproteinases and their inhibitors in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The clinicopathological and prognostic significance of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-9 according to their localization in invasive breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Genetic polymorphisms in the MMP-7 gene and breast cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Study of matrix metalloproteinases and their inhibitors in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Elevated serum matrix metalloproteinase 7 levels predict poor prognosis after radical prostatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Validation of circulating MMP-7 level as an independent prognostic marker of poor survival in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinases and angiogenic factors: predictors of survival after radical prostatectomy for clinically organ-confined prostate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

The other side of MMPs: protective roles in tumor progression

21 January 2018

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https://api.crossref.org/works/10.1007/S13277-013-0842-8

Strategies for MMP inhibition in cancer: innovations for the post-trial era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Matrix metalloproteinase proteomics: substrates, targets, and therapy.

21 January 2018

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https://api.crossref.org/works/10.1007/S13277-013-0842-8

Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Tissue inhibitor of metalloproteinase 1 is an independent predictor of prognosis in patients with nonsmall cell lung carcinoma who undergo resection with curative intent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Structural Differences of Matrix Metalloproteinases with Potential Implications for Inhibitor Selectivity Examined by the GRID/CPCA Approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S13277-013-0842-8

Quantitative reverse zymography: analysis of picogram amounts of metalloproteinase inhibitors using gelatinase A and B reverse zymograms

21 January 2018

1 reference

12 December 2020

Urinary biomarkers predict brain tumor presence and response to therapy

1 reference

12 December 2020

Expression of KISS1 and MMP-9 in non-small cell lung cancer and their relations to metastasis and survival

1 reference

12 December 2020

Predictive value of MMP-7 expression for response to chemotherapy and survival in patients with non-small cell lung cancer

1 reference

12 December 2020

Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells

1 reference

12 December 2020

Expression and clinical significance of matrix metalloproteinase (MMP)-26 protein in non-small cell lung cancer

1 reference

12 December 2020

Stromelysin 3 expression: a useful marker for the differential diagnosis dermatofibroma versus dermatofibrosarcoma protuberans

1 reference

12 December 2020

Expression of matrix metalloproteinases 7 and 9 in non-small cell lung cancer. Relation to clinicopathological factors, beta-catenin and prognosis

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12 December 2020

Activity of MMP-2 and MMP-9 in sera of breast cancer patients

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12 December 2020

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

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12 December 2020

MMP-9 (gelatinase B) expression is associated with disease-free survival and disease-specific survival in colorectal cancer patients

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12 December 2020

Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1

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12 December 2020

Elevated levels of serum metalloproteinase 9 in patients with esophageal squamous cell carcinoma

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12 December 2020

Collagenase-3 expression by tumor cells and gelatinase B expression by stromal fibroblast-like cells are associated with biochemical recurrence after radical prostatectomy in patients with prostate cancer

1 reference

12 December 2020

Expression of potential molecular markers in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy

1 reference

12 December 2020

Identification and classification of differentially expressed genes in non-small cell lung cancer by expression profiling on a global human 59.620-element oligonucleotide array.

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12 December 2020

Alternative splicing variant of vascular endothelial growth factor-A is a critical prognostic factor in non-small cell lung cancer.

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12 December 2020

Clinicopathologic and prognostic significance of matrilysin expression at the invasive front in human colorectal cancers

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12 December 2020

MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer

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12 December 2020

Overexpression of matrix metalloproteinase-7 (MMP-7) correlates with tumor proliferation, and a poor prognosis in non-small cell lung cancer

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12 December 2020

Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.

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12 December 2020

Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma

1 reference

12 December 2020

Serum matrix metalloproteinases -2, -9 and tissue inhibitors of metalloproteinases -1, -2 in lung cancer--TIMP-1 as a prognostic marker

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12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

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12 December 2020

Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease.

1 reference

12 December 2020

The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis

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12 December 2020

Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer

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12 December 2020

Expression of HIF-1alpha, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer

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12 December 2020

Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis.

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12 December 2020

Circulating MMP2 and MMP9 in breast cancer -- potential role in classification of patients into low risk, high risk, benign disease and breast cancer categories

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12 December 2020

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

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12 December 2020

Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance

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12 December 2020

Matrix Metalloproteinase-9 Is a Prognostic Marker to Predict Survival of Patients Who Underwent Surgery Due to Rectal Carcinoma

1 reference

12 December 2020

Matrix metalloproteinases as diagnostic (MMP-13) and prognostic (MMP-2, MMP-9) markers of prostate cancer

1 reference

12 December 2020

Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer

1 reference

12 December 2020

Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer

1 reference

12 December 2020

Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells.

1 reference

12 December 2020

Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database

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12 December 2020

Experimental metastasis is suppressed in MMP-9-deficient mice

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12 December 2020

Prognostic relevance of TTF-1 and MMP-9 expression in advanced lung adenocarcinoma

1 reference

12 December 2020

Clinical Significance of the Measurements of Serum Matrix Metalloproteinase-9 and Its Inhibitor (Tissue Inhibitor of Metalloproteinase-1) in Patients With Pancreatic Cancer

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12 December 2020

Prognostic value of matrix metalloproteinase 9 expression in patients with non-small cell lung cancer

1 reference

12 December 2020

Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice

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12 December 2020

Noninvasive diagnosis of bladder cancer by detection of matrix metalloproteinases (MMP-2 and MMP-9) and their inhibitor (TIMP-2) in urine

1 reference

12 December 2020

The diagnostic value of the measurement of matrix metalloproteinase 9 (MMP-9), squamous cell cancer antigen (SCC) and carcinoembryonic antigen (CEA) in the sera of esophageal cancer patients

1 reference

12 December 2020

Expression of metalloproteases and their inhibitors in primary tumors and in local recurrences after mastectomy for breast cancer

1 reference

12 December 2020

CD147, MMP-1, MMP-2 and MMP-9 protein expression as significant prognostic factors in human prostate cancer

1 reference

12 December 2020

MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone

1 reference

12 December 2020

10.1007/S13277-013-0842-8

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1004513159

0 references

1 reference