The role of the podocyte in albumin filtration (Q38100984)

28 August 2017

title

The role of the podocyte in albumin filtration (English)

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28 August 2017

3

Thomas Benzing

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28 August 2017

author name string

Paul Thomas Brinkkoetter

series ordinal

1

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28 August 2017

Christina Ising

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

23 April 2013

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Nature Reviews Nephrology

28 August 2017

published in

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28 August 2017

volume

9

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28 August 2017

issue

6

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28 August 2017

page(s)

328-336

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Properties of the glomerular barrier and mechanisms of proteinuria

28 August 2017

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Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

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Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis

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Clinical impact of research on the podocyte slit diaphragm

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Role for a Cindr–Arf6 axis in patterning emerging epithelia

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Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye.

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The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins

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Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of theDrosophilaretinotopic map

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The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein

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The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm

31 March 2020

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Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes.

31 March 2020

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The Drosophila nephrocyte

31 March 2020

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The irre cell recognition module (IRM) proteins

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space

31 March 2020

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Why the kidney glomerulus does not clog: a gel permeation/diffusion hypothesis of renal function

31 March 2020

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Model of albumin reabsorption in the proximal tubule

31 March 2020

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Glomerular filtration of albumin: how small is the sieving coefficient?

31 March 2020

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Electrical Forces Determine Glomerular Permeability

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Donor splice-site mutations in WT1 are responsible for Frasier syndrome

31 March 2020

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WT1 splice-site mutations are rarely associated with primary steroid-resistant focal and segmental glomerulosclerosis.

31 March 2020

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Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

31 March 2020

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Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS)

31 March 2020

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Genotype-phenotype correlations in non-Finnish congenital nephrotic syndrome

31 March 2020

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Podocin localizes in the kidney to the slit diaphragm area

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation

31 March 2020

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Early Homo and associated artefacts from Asia

31 March 2020

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Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

31 March 2020

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TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology

31 March 2020

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The podocyte's response to injury: role in proteinuria and glomerulosclerosis

31 March 2020

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The podocyte's response to stress: the enigma of foot process effacement

31 March 2020

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Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

31 March 2020

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Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.

31 March 2020

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Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

31 March 2020

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Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival

31 March 2020

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VEGF inhibition and renal thrombotic microangiopathy

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31 March 2020

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

31 March 2020

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Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca2 and RhoA activation

31 March 2020

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Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Mechanisms of the proteinuria induced by Rho GTPases

31 March 2020

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Activation of RhoA in podocytes induces focal segmental glomerulosclerosis

31 March 2020

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mTOR signaling in growth control and disease

31 March 2020

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Inhibition of MTOR disrupts autophagic flux in podocytes

31 March 2020

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mToR inhibitors-induced proteinuria: mechanisms, significance, and management

31 March 2020

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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

31 March 2020

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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

31 March 2020

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Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria

31 March 2020

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Proteinuria and immunity--an overstated relationship?

31 March 2020

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Nephrin deficiency activates NF-kappaB and promotes glomerular injury

31 March 2020

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Podocytes: gaining a foothold.

31 March 2020

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An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms

31 March 2020

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Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

31 March 2020

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Role of the polarity protein Scribble for podocyte differentiation and maintenance

31 March 2020

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Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity

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Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells

31 March 2020

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p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo.

31 March 2020

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Apoptosis in podocytes induced by TGF-beta and Smad7

31 March 2020

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Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

31 March 2020

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Cyclin-dependent kinase 5 supports neuronal survival through phosphorylation of Bcl-2.

31 March 2020

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Pathology of Human Diabetic Nephropathy

31 March 2020

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Cumulative excretion of urinary podocytes reflects disease progression in IgA nephropathy and Schönlein-Henoch purpura nephritis

31 March 2020

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Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions.

31 March 2020

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Imaging of podocyte foot processes by fluorescence microscopy

31 March 2020

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A high-powered view of the filtration barrier

31 March 2020

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The first decade of using multiphoton microscopy for high-power kidney imaging

31 March 2020

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Multiphoton imaging of the glomerular permeability of angiotensinogen

31 March 2020

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Fishing for new glomerular disease-related genes

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

The podocyte as a target for therapies—new and old

31 March 2020

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A photo shoot of proteinuria: zebrafish models of inducible podocyte damage

31 March 2020

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Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes

31 March 2020

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Rapid screening of glomerular slit diaphragm integrity in larval zebrafish

31 March 2020

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Inducible podocyte injury and proteinuria in transgenic zebrafish

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility

31 March 2020

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Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities

31 March 2020

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MYO1E mutations and childhood familial focal segmental glomerulosclerosis

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Disruption of PTPRO causes childhood-onset nephrotic syndrome

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome

31 March 2020

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Mutation analysis of LMX1B gene in nail-patella syndrome patients

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome

31 March 2020

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Mutant chromatin remodeling protein SMARCAL1 causes Schimke immuno-osseous dysplasia.

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency

31 March 2020

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https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

A case of mitochondrial cytopathy with a typical point mutation for MELAS, presenting with severe focal-segmental glomerulosclerosis as main clinical manifestation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

A nonsense mutation in the LIMP-2 gene associated with progressive myoclonic epilepsy and nephrotic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Mutations in FN1 cause glomerulopathy with fibronectin deposits.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRNEPH.2013.78

Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor

31 March 2020

1 reference

12 December 2020

A stomatin-like protein necessary for mechanosensation in C. elegans

1 reference

12 December 2020

Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm

1 reference

12 December 2020

The nephropathy associated with male pseudohermaphroditism and Wilms' tumor (Drash syndrome): a distinctive glomerular lesion--report of 10 cases

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12 December 2020

Intrarenal handling of proteins in rats using fractional micropuncture technique

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12 December 2020

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

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12 December 2020

rst and its paralogue kirre act redundantly during embryonic muscle development in Drosophila

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12 December 2020

Some features of glomerular filtration and permeability revealed by electron microscopy after intraperitoneal injection of dextran in rats.

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12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2013.78

1 reference

28 August 2017

1 reference