Follistatin as potential therapeutic target in prostate cancer (Q38086102)

28 August 2017

title

Follistatin as potential therapeutic target in prostate cancer (English)

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28 August 2017

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Maria Vittoria Sepporta

1

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28 August 2017

Francesca Maria Tumminello

2

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28 August 2017

Carla Flandina

3

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28 August 2017

Marilena Crescimanno

4

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28 August 2017

Marco Giammanco

5

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28 August 2017

Maurizio La Guardia

6

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28 August 2017

Danila di Majo

7

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28 August 2017

Gaetano Leto

8

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28 August 2017

publication date

1 March 2013

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28 August 2017

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28 August 2017

volume

8

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28 August 2017

issue

4

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28 August 2017

page(s)

215-223

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Estimates of the cancer incidence and mortality in Europe in 2006.

28 August 2017

cites work

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Signal transduction in prostate cancer progression

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Activins and inhibins in endocrine and other tumors

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The contribution of inhibins and activins to malignant prostate disease

21 January 2018

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Activins and activin antagonists in the prostate and prostate cancer

21 January 2018

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Follistatin: a multifunctional regulatory protein

21 January 2018

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Multiple defects and perinatal death in mice deficient in follistatin

21 January 2018

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Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function

21 January 2018

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https://api.crossref.org/works/10.1007/S11523-013-0268-7

FoxL2 and Smad3 coordinately regulate follistatin gene transcription

21 January 2018

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Transcriptional regulation of follistatin expression by GnRH in mouse gonadotroph cell lines: evidence for a role for cAMP signaling

21 January 2018

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GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells

21 January 2018

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BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: potential therapeutic targets for glucocorticoid-induced osteoporosis

21 January 2018

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Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways

21 January 2018

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A transcriptional response to Wnt protein in human embryonic carcinoma cells

21 January 2018

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Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis

21 January 2018

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Peroxisome proliferator-activated receptor gamma down-regulates follistatin in intestinal epithelial cells through SP1

21 January 2018

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1,25(OH)2Vitamin D3 Stimulates Myogenic Differentiation by Inhibiting Cell Proliferation and Modulating the Expression of Promyogenic Growth Factors and Myostatin in C2C12 Skeletal Muscle Cells

21 January 2018

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Sp6 downregulation of follistatin gene expression in ameloblasts

21 January 2018

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Differential distribution of follistatin isoforms: application of a new FS315-specific immunoassay

21 January 2018

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The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding

21 January 2018

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Rat follistatin: gonadal and extragonadal expression and evidence for alternative splicing.

21 January 2018

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Structural basis for the inhibition of activin signalling by follistatin.

21 January 2018

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Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions

21 January 2018

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Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin, and bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

21 January 2018

1 reference

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Follistatin regulates bone morphogenetic protein-7 (BMP-7) activity to stimulate embryonic muscle growth.

21 January 2018

1 reference

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Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin.

21 January 2018

1 reference

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Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis

21 January 2018

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Follistatin antagonizes transforming growth factor-beta3-induced epithelial-mesenchymal transition in vitro: implications for murine palatal development supported by microarray analysis.

21 January 2018

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https://api.crossref.org/works/10.1007/S11523-013-0268-7

Identification and characterization of follistatin as a novel angiogenin-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Expression patterns of activin, inhibin and follistatin variants in the adult male mouse reproductive tract suggest important roles in the epididymis and vas deferens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Inhibins, activins, and follistatins: expression of mRNAs and cellular localization in tissues from men with benign prostatic hyperplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Regulation of prostate branching morphogenesis by activin A and follistatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Molecular signaling pathways that regulate prostate gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Role of stroma in carcinogenesis of the prostate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Conserved gene expression programs integrate mammalian prostate development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Dedifferentiation of stromal smooth muscle as a factor in prostate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Differentially expressed genes in two LNCaP prostate cancer cell lines reflecting changes during prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Sex hormone metabolism in prostate cancer cells during transition to an androgen-independent state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

A dormant state modulated by osmotic pressure controls clonogenicity of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Endogenous bone morphogenetic protein-7 controls the motility of prostate cancer cells through regulation of bone morphogenetic protein antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Nucleolar Follistatin Promotes Cancer Cell Survival under Glucose-deprived Conditions through Inhibiting Cellular rRNA Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Angiogenin as a Molecular Target for the Treatment of Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

A therapeutic target for prostate cancer based on angiogenin-stimulated angiogenesis and cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

More than an accessory: implications of type III transforming growth factor-beta receptor loss in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Differential gene expression by endothelial cells in distinct angiogenic states

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Mechanisms of action of angiogenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Dissociation of angiogenesis and tumorigenesis in follistatin- and activin-expressing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Tumor Angiogenesis as a Target for Dietary Cancer Prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Upregulated INHBA expression may promote cell proliferation and is associated with poor survival in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Neuroblastoma angiogenesis is inhibited with a folded synthetic molecule corresponding to the epidermal growth factor-like module of the follistatin domain of SPARC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Activin A stimulates AKR1C3 expression and growth in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Deregulation of the activin/follistatin system in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Proteomic analysis of conditioned media from the PC3, LNCaP, and 22Rv1 prostate cancer cell lines: discovery and validation of candidate prostate cancer biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Serum follistatin in patients with prostate cancer metastatic to the bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Changes in extracellular activin A:follistatin ratio during differentiation of a mesenchymal progenitor cell line, ROB-C26 into osteoblasts and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

The activin A-follistatin system: potent regulator of human extracellular matrix mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Follistatin as a potent regulator of bone metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Bone morphogenetic proteins and its receptors; therapeutic targets in cancer progression and bone metastasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Activin receptor signaling regulates prostatic epithelial cell adhesion and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Validation of a multiplex immunoassay for serum angiogenic factors as biomarkers for aggressive prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Activin A circulating levels in patients with bone metastasis from breast or prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Plasma Concentrations of Angiogenesis-related Molecules in Patients with Pancreatic Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11523-013-0268-7

Follistatin and its role as an activin-binding protein

21 January 2018

1 reference

12 December 2020

Difference between follistatin isoforms in the inhibition of activin signalling: activin neutralizing activity of follistatin isoforms is dependent on their affinity for activin

1 reference

12 December 2020

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression

1 reference

12 December 2020

Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in androgen-independent PC-3 human prostate cancer cells

1 reference

12 December 2020

Predicting the treatment effect of sorafenib using serum angiogenesis markers in patients with hepatocellular carcinoma

1 reference

12 December 2020

Identification of an activin-follistatin growth modulatory system in the human prostate: secretion and biological activity in primary cultures of prostatic epithelial cells

1 reference

12 December 2020

Follistatin and activin A production by the male reproductive tract

1 reference

12 December 2020

Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium

1 reference

12 December 2020

Expression of activin A and follistatin core proteins by human prostate tumor cell lines

1 reference

12 December 2020

Follistatin-activin complexes in human serum and follicular fluid differ immunologically and biochemically

1 reference

12 December 2020

Rapamycin induces Smad activity in prostate cancer cell lines

1 reference

12 December 2020

Inhibin, activin and follistatin bind preferentially to the transformed species of alpha 2-macroglobulin

1 reference

12 December 2020

Localization of the heparin binding site of follistatin

1 reference

12 December 2020

Carcinoma of the prostate: overview of the most common malignancy in men.

1 reference

12 December 2020

A Two-Site Chemiluminescent Assay for Activin-Free Follistatin Reveals That Most Follistatin Circulating in Men and Normal Cycling Women Is in an Activin-Bound State1

1 reference

12 December 2020

The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis

1 reference

12 December 2020

Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell

1 reference

12 December 2020

Emerging concepts: linking hypoxic signaling and cancer metabolism.

1 reference

12 December 2020

The influence of follistatin on mechanical properties of bone tissue in growing mice with overexpression of follistatin

1 reference

12 December 2020

10.1007/S11523-013-0268-7

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

1005464409

0 references

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