Chemical genetics of acetyl-CoA carboxylases. (Q38077441)

PubMed publication ID

28 August 2017

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title

Chemical genetics of acetyl-CoA carboxylases (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6269866&resulttype=core&format=json

13 May 2020

author name string

Xuyu Zu

1

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13 May 2020

Jing Zhong

2

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13 May 2020

Dixian Luo

3

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13 May 2020

Jingjing Tan

4

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13 May 2020

Qinghai Zhang

5

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13 May 2020

Ying Wu

6

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13 May 2020

Jianghua Liu

7

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13 May 2020

Renxian Cao

8

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13 May 2020

Gebo Wen

9

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13 May 2020

Deliang Cao

10

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13 May 2020

language of work or name

English

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publication date

28 January 2013

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PubMed publication ID

28 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6269866&resulttype=core&format=json

13 May 2020

volume

18

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13 May 2020

issue

2

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13 May 2020

page(s)

1704-1719

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Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

28 January 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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Inhibitory effects of long-chain acyl coenzyme a analogues on rat liver acetyl coenzyme a carboxylase

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Membrane raft microdomains mediate front-rear polarity in migrating cells

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Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells

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Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility

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Interaction of the fluorescent analogue stearoyl-(1,N6)-etheno coenzyme A with chicken liver acetyl coenzyme A carboxylase

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The risk of a contralateral breast cancer among women diagnosed with ductal and lobular breast carcinoma in situ: data from the Connecticut Tumor Registry

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Selective activation of the fatty acid synthesis pathway in human prostate cancer

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Cloning of human acetyl-CoA carboxylase beta promoter and its regulation by muscle regulatory factors

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Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase

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Increased lipogenesis in cancer cells: new players, novel targets.

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Acetyl-CoA carboxylase beta gene is regulated by sterol regulatory element-binding protein-1 in liver

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Liver and adipose tissue contributions to newly formed fatty acids in an ascites tumor

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Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis

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Acetyl-coenzyme A carboxylases: versatile targets for drug discovery

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On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA

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AMP-activated protein kinase, super metabolic regulator

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5-(Tetradecyloxy)-2-furancarboxylic acid and related hypolipidemic fatty acid-like alkyloxyarylcarboxylic acids

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Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells

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12 December 2020

A diverse superfamily of enzymes with ATP‐dependent carboxylate—amine/thiol ligase activity

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12 December 2020

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma

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Thia fatty acids, metabolism and metabolic effects

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12 December 2020

BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains

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12 December 2020

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

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12 December 2020

Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle

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12 December 2020

Soraphen, an inhibitor of the acetyl-CoA carboxylase system, improves peripheral insulin sensitivity in mice fed a high-fat diet.

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12 December 2020

A biotin analog inhibits acetyl-CoA carboxylase activity and adipogenesis

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12 December 2020

Metabolism of neoplastic tissue. IV. A study of lipid synthesis in neoplastic tissue slices in vitro

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12 December 2020

Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A. Formation of Equimolar Enzyme-Inhibitor Complex

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12 December 2020

Regulation of mammalian acetyl-coenzyme A carboxylase

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Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression

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12 December 2020

Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention

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12 December 2020

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

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Sensitization to Insulin Induced by β,β′-Methyl-Substituted Hexadecanedioic Acid (MEDICA 16) in Obese Zucker Rats In Vivo

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Metabolic effects of thia fatty acids

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Secretion of apolipoproteins A-I and B by HepG2 cells: regulation by substrates and metabolic inhibitors

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Mitochondria Uncoupling by a Long Chain Fatty Acyl Analogue

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Involvement of long-chain acyl coenzyme A for lipid synthesis in repression of acetyl-coenzyme A carboxylase in Candida lipolytica

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Identification and Characterization of a Novel Human Aldose Reductase-like Gene

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12 December 2020

The “Spot 14” gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: Implications for control of tumor metabolism

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12 December 2020

Acetyl-CoA carboxylase inhibition for the treatment of metabolic syndrome.

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12 December 2020

Regulation of mammalian acetyl-CoA carboxylase

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12 December 2020

Hypolipidemic, antiobesity, and hypoglycemic-hypoinsulinemic effects of beta,beta'-methyl-substituted hexadecanedioic acid in sand rats

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12 December 2020

Purification and characterization of intact and truncated forms of the Escherichia coli biotin carboxyl carrier subunit of acetyl-CoA carboxylase

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12 December 2020

The biochemistry of hypo- and hyperlipidemic fatty acid derivatives: metabolism and metabolic effects

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12 December 2020

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

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12 December 2020

Effect of phosphorylation by AMP-activated protein kinase on palmitoyl-CoA inhibition of skeletal muscle acetyl-CoA carboxylase

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12 December 2020

Fatty acid synthesis and its regulation

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12 December 2020

Requirement for a malonyl CoA-CO2 exchange reaction in long chain but not short chain fatty acid synthesis in Clostridium Kluvveri

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12 December 2020

Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals

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12 December 2020

BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase

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12 December 2020

Inhibition of fatty acid synthesis decreases very low density lipoprotein secretion in the hamster

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12 December 2020

Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase

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12 December 2020

Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation

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12 December 2020

Structure and regulation of acetyl-CoA carboxylase genes of metazoa

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12 December 2020

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

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12 December 2020

Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.

1 reference

12 December 2020

Metabolic labelling of membrane microdomains/rafts in Jurkat cells indicates the presence of glycerophospholipids implicated in signal transduction by the CD3 T-cell receptor

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12 December 2020

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

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12 December 2020

AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome

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12 December 2020

Androgens, lipogenesis and prostate cancer.

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12 December 2020

Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription

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12 December 2020

Synthesis of the optical isomers of 4-[1-(4-tert-butylphenyl)-2-oxo- pyrrolidine-4-yl]methyloxybenzoic acid (S-2) and their biological evaluation as antilipidemic agent

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12 December 2020

A new dominant selection marker for transformation of Pichia pastoris to soraphen A resistance.

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12 December 2020

Inhibition of beta-oxidative respiration is a therapeutic window associated with the cancer chemo-preventive activity of PPARgamma agonists.

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Why Syndrome X? From Harold Himsworth to the insulin resistance syndrome

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12 December 2020

A novel acetyl-CoA carboxylase inhibitor reduces de novo fatty acid synthesis in HepG2 cells and rat primary hepatocytes

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12 December 2020

Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition

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12 December 2020

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

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12 December 2020

Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in the rat in vivo

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12 December 2020

Dietary supplementation with alpha-amylase inhibitor wheat albumin to high-fat diet-induced insulin-resistant rats is associated with increased expression of genes related to fatty acid synthesis in adipose tissue

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12 December 2020

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase

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12 December 2020

Anti-obesity activity of a novel lipid synthesis inhibitor

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12 December 2020

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

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12 December 2020

Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery

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12 December 2020

The effect of beta,beta'-tetramethylhexadecanedioic acid (MEDICA 16) on plasma very-low-density lipoprotein metabolism in rats: role of apolipoprotein C-III.

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12 December 2020

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

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12 December 2020

Asymmetric total synthesis of soraphen A: a flexible alkyne strategy

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12 December 2020

Lipid rafts and signal transduction

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12 December 2020

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12 December 2020

Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16

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12 December 2020

Acetyl coenzyme A carboxylase. Molecular forms and subunit composition of biotin carboxyl carrier protein

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12 December 2020

AKR1B10 overexpression in breast cancer: Association with tumor size, lymph node metastasis and patient survival and its potential as a novel serum marker

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12 December 2020

Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid

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12 December 2020

Citrate inhibition of rat-kidney cortex phosphofructokinase

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12 December 2020

A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product.

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12 December 2020

Mechanism responsible for 5-(tetradecyloxy)-2-furoic acid inhibition of hepatic lipogenesis

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12 December 2020

Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival

1 reference

12 December 2020

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

1 reference

12 December 2020

Biotin carboxylase comes into the fold

1 reference

12 December 2020

Interactions between fatty acid synthesis, oxidation, and esterification in the production of triglyceride-rich lipoproteins by the liver

1 reference

12 December 2020

Kinetic and structural analysis of a new group of Acyl-CoA carboxylases found in Streptomyces coelicolor A3(2).

1 reference

12 December 2020

Broad specificity of carnitine palmitoyltransferase II towards long-chain acyl-CoA beta-oxidation intermediates and its practical approach to the synthesis of various long-chain acylcarnitines

1 reference

12 December 2020

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

1 reference

12 December 2020

Inhibition of Atherosclerosis and Myocardial Lesions in the JCR:LA-cp Rat by β,β′-Tetramethylhexadecanedioic Acid (MEDICA 16)

1 reference

12 December 2020

Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosis

1 reference

12 December 2020

Expression and characterization of recombinant fungal acetyl-CoA carboxylase and isolation of a soraphen-binding domain

1 reference

12 December 2020

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

1 reference

12 December 2020

SREBP transcription factors: master regulators of lipid homeostasis

1 reference

12 December 2020

Movement of the biotin carboxylase B-domain as a result of ATP binding

1 reference

12 December 2020

Aldo-keto reductase family 1 member B10 promotes cell survival by regulating lipid synthesis and eliminating carbonyls

1 reference

12 December 2020

Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1

1 reference

12 December 2020

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase

1 reference

12 December 2020

Control of lipid metabolism in hepatomas: insensitivity of rate of fatty acid and cholesterol synthesis by mouse hepatoma BW7756 to fasting and to feedback control.

1 reference

12 December 2020

10.3390/MOLECULES18021704

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6269866&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6269866&resulttype=core&format=json

13 May 2020

PubMed publication ID

23358327

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6269866&resulttype=core&format=json