Effects of vitamin D on immune disorders with special regard to asthma, COPD and autoimmune diseases: a short review (Q38066985)

28 August 2017

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title

Effects of vitamin D on immune disorders with special regard to asthma, COPD and autoimmune diseases: a short review (English)

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chronic obstructive pulmonary disease

28 August 2017

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Joseph I Székely

1

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28 August 2017

Ágnes Pataki

series ordinal

2

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28 August 2017

publication date

1 December 2012

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Expert Review of Respiratory Medicine

28 August 2017

published in

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28 August 2017

volume

6

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28 August 2017

issue

6

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28 August 2017

page(s)

683-704

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Noncalcemic Actions of Vitamin D Receptor Ligands

28 August 2017

cites work

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The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer

21 January 2018

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DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27

21 January 2018

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In vitro model of vitamin D3 (cholecalciferol) synthesis by UV radiation: dose-response relationships

21 January 2018

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Sunny hours and variations in the prevalence of asthma in schoolchildren according to the International Study of Asthma and Allergies (ISAAC) Phase III in Spain

21 January 2018

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Vitamin D signaling, infectious diseases, and regulation of innate immunity

21 January 2018

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Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity

21 January 2018

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Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase

21 January 2018

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Enzymes involved in the activation and inactivation of vitamin D.

21 January 2018

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Metabolism of vitamin D by human microsomal CYP2R1.

21 January 2018

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Minireview: vitamin D receptor: new assignments for an already busy receptor

21 January 2018

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A systematic review of the association between common single nucleotide polymorphisms and 25-hydroxyvitamin D concentrations

21 January 2018

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Vitamin D status: measurement, interpretation, and clinical application

21 January 2018

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25-hydroxyvitamin D levels and the risk of mortality in the general population

21 January 2018

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1alpha,25-dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility, and remodeling processes.

21 January 2018

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Renal adenylate cyclase and the interrelationship between parathyroid hormone and vitamin D in the regulation of urinary phosphate and adenosine cyclic 3',5'-monophosphate excretion

21 January 2018

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Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction

21 January 2018

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Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes

21 January 2018

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Plasma concentrations of 25-hydroxy-vitamin D and 1,25-dihydroxy-vitamin D are related to the phenotype of Gc (vitamin D-binding protein): a cross-sectional study on 595 early postmenopausal women

21 January 2018

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Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes

21 January 2018

1 reference

Is vitamin D deficiency to blame for the asthma epidemic?

21 January 2018

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Vitamin D and asthma: time for intervention?

21 January 2018

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Socio-environmental conditions and geographical variability of asthma prevalence in Northeast Brazil

21 January 2018

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Genetic and non-genetic correlates of vitamins K and D.

21 January 2018

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Common genetic determinants of vitamin D insufficiency: a genome-wide association study

21 January 2018

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Genome-wide association study of circulating vitamin D levels

21 January 2018

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Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study

21 January 2018

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Common variation in vitamin D pathway genes predicts circulating 25-hydroxyvitamin D Levels among African Americans.

21 January 2018

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Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

21 January 2018

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Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.

21 January 2018

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

21 January 2018

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Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions.

21 January 2018

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Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription.

21 January 2018

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Vitamin effects on the immune system: vitamins A and D take centre stage

21 January 2018

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Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes

21 January 2018

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25-Hydroxyvitamin D 3 1α-Hydroxylase and Vitamin D Synthesis

21 January 2018

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Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.

21 January 2018

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Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway

21 January 2018

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Toward a comprehensive set of asthma susceptibility genes

21 January 2018

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Vitamin D and human health: lessons from vitamin D receptor null mice.

21 January 2018

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Quantification of the vitamin D receptor-coregulator interaction

21 January 2018

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Vitamin D and respiratory health

21 January 2018

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Innate antimicrobial peptide protects the skin from invasive bacterial infection

21 January 2018

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Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis

21 January 2018

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Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor.

21 January 2018

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Defensins: antimicrobial peptides of innate immunity

21 January 2018

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Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes

21 January 2018

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The role of cathelicidin and defensins in pulmonary inflammatory diseases.

21 January 2018

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Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3).

21 January 2018

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Mechanisms underlying the effect of vitamin D on the immune system

21 January 2018

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Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation

21 January 2018

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Intervention in autoimmunity: the potential of vitamin D receptor agonists

21 January 2018

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Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts

21 January 2018

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Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns.

21 January 2018

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Intravenous immunoglobulin attenuates airway inflammation through induction of forkhead box protein 3-positive regulatory T cells

21 January 2018

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TGF-beta induces Foxp3 T-regulatory cells from CD4 CD25 - precursors

21 January 2018

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Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

21 January 2018

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Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting autoimmune diabetes

21 January 2018

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Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4 Foxp3 regulatory T cells by 1,25-dihydroxyvitamin D3.

21 January 2018

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Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity.

21 January 2018

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1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

21 January 2018

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High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells

21 January 2018

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1,25-Dihydroxyvitamin D3Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

21 January 2018

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Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells

21 January 2018

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Immunologic self-tolerance maintained by CD25( )CD4( ) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

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In vitro generation of interleukin 10-producing regulatory CD4( ) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

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Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

21 January 2018

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Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.

21 January 2018

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Natural interferon alpha/beta-producing cells link innate and adaptive immunity

21 January 2018

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CD4 CD25 immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

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The role of interleukin 10 in the control of autoimmunity.

21 January 2018

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The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells

21 January 2018

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The maintenance of human CD4 CD25 regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro.

21 January 2018

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The genes encoding cytokines IL-2, IL-10 and IL-12B are primary 1alpha,25(OH)2D3 target genes

21 January 2018

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Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

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The role of different subsets of T regulatory cells in controlling autoimmunity

21 January 2018

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Differentiation of T regulatory cells by immature dendritic cells

21 January 2018

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Immunomodulatory role of 1,25-dihydroxyvitamin D3.

21 January 2018

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Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.

21 January 2018

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Immunobiology of lnterleukin-12

21 January 2018

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1 alpha,25-Dihydroxyvitamin D3 inhibits gamma-interferon synthesis by normal human peripheral blood lymphocytes

21 January 2018

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Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease.

21 January 2018

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1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells

21 January 2018

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The anti-inflammatory effects of 1,25-dihydroxyvitamin D3 on Th2 cells in vivo are due in part to the control of integrin-mediated T lymphocyte homing

21 January 2018

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In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice

21 January 2018

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Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR CD4-CD8-T cells

21 January 2018

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Interleukin 17-producing CD4 effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

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Th17 T cells: linking innate and adaptive immunity

21 January 2018

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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

21 January 2018

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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

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The Current STATus of lymphocyte signaling: new roles for old players.

21 January 2018

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

21 January 2018

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TH17 cells in development: an updated view of their molecular identity and genetic programming

21 January 2018

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Induction and effector functions of T(H)17 cells.

21 January 2018

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The interleukin-23 axis in intestinal inflammation

21 January 2018

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Vitamin D suppresses Th17 cytokine production by inducing C/EBP homologous protein (CHOP) expression

21 January 2018

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Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response

21 January 2018

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1,25-dihydroxyvitamin D3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis

21 January 2018

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1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells

21 January 2018

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Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling

21 January 2018

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Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis

21 January 2018

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Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.

21 January 2018

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1,25-Dihydroxyvitamin D3--a hormone with immunomodulatory properties

21 January 2018

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Vitamin D receptor activation improves allergen-triggered eczema in mice.

21 January 2018

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Gene regulation by 1,25-dihydroxyvitamin D3 in CD4 CD25 cells is enabled by IL-2.

21 January 2018

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Differential Effects of Peptidoglycan Recognition Proteins on Experimental Atopic and Contact Dermatitis Mediated by Treg and Th17 Cells

21 January 2018

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Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene

21 January 2018

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Vitamin D deficiency causes deficits in lung function and alters lung structure

21 January 2018

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1,25-Dihydroxyvitamin D3 prevented allergic asthma in a rat model by suppressing the expression of inducible nitric oxide synthase

21 January 2018

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The role of vitamin D in asthma

21 January 2018

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Vitamin D - a new treatment for airway remodelling in asthma?

21 January 2018

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Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1

21 January 2018

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Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

21 January 2018

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Umbilical cord plasma 25-hydroxyvitamin D concentration and immune function at birth: the Urban Environment and Childhood Asthma study

21 January 2018

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21 January 2018

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Vitamin D levels, lung function, and steroid response in adult asthma

21 January 2018

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Heritability and environmental factors affecting vitamin D status in rural Chinese adolescent twins

21 January 2018

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Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma

21 January 2018

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Cord blood 25-hydroxyvitamin D levels are associated with aeroallergen sensitization in children from Tucson, Arizona

21 January 2018

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Genetics and biology of vitamin D receptor polymorphisms

21 January 2018

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Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis

21 January 2018

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Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy

21 January 2018

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Association of vitamin D receptor gene polymorphisms with childhood and adult asthma

21 January 2018

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Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations

21 January 2018

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Variants in the vitamin D receptor gene and asthma

21 January 2018

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Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population: a case-control study

21 January 2018

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The vitamin D axis in the lung: a key role for vitamin D-binding protein

21 January 2018

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Vitamin D deficiency as a strong predictor of asthma in children

21 January 2018

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Single nucleotide polymorphism screening and association analysis--exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthma

21 January 2018

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High Prevalence of Vitamin D Inadequacy and Implications for Health

21 January 2018

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High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC

21 January 2018

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Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study

21 January 2018

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The relationship between serum 25 hydroxy vitamin d levels and asthma in children.

21 January 2018

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Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma

21 January 2018

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Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination survey

21 January 2018

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Infant vitamin d supplementation and allergic conditions in adulthood: northern Finland birth cohort 1966.

21 January 2018

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Childhood asthma may be a consequence of vitamin D deficiency

21 January 2018

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Nutrients and foods for the primary prevention of asthma and allergy: systematic review and meta-analysis

21 January 2018

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Relationship of maternal vitamin D level with maternal and infant respiratory disease

21 January 2018

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Early-life supplementation of vitamins A and D, in water-soluble form or in peanut oil, and allergic diseases during childhood.

21 January 2018

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Maternal vitamin D status during pregnancy and child outcomes.

21 January 2018

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Diet for the prevention of asthma and allergies in early childhood: much ado about something?

21 January 2018

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21 January 2018

COPD and osteoporosis

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North-south differences in US emergency department visits for acute allergic reactions

21 January 2018

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Make no bones about it: increasing epidemiologic evidence links vitamin D to pulmonary function and COPD.

21 January 2018

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Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies

21 January 2018

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Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study

21 January 2018

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The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease: a cross sectional study.

21 January 2018

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Low bone mineral density in men with chronic obstructive pulmonary disease

21 January 2018

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Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation

21 January 2018

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Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele

21 January 2018

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21 January 2018

Vitamin D insufficiency.

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1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis

21 January 2018

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1,25 Dihydroxyvitamin D3 exerts regional effects in the central nervous system during experimental allergic encephalomyelitis

21 January 2018

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The role of vitamin D in multiple sclerosis.

21 January 2018

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Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis

21 January 2018

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A Crucial Role for the Vitamin D Receptor in Experimental Inflammatory Bowel Diseases

21 January 2018

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Mechanisms of disease: vitamin D and inflammatory bowel disease

21 January 2018

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Prolongation of allograft survival by 1,25-dihydroxyvitamin D3.

21 January 2018

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1alpha,25-dihydroxyvitamin D3 shows strong and additive immunomodulatory effects with cyclosporine A in rat renal allotransplants

21 January 2018

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Prevention of chronic allograft nephropathy with vitamin D.

21 January 2018

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Improved renal allograft survival with vitamin D receptor polymorphism

21 January 2018

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Vitamin D and the adaptive immune system with special emphasis to allergic reactions and allograft rejection

21 January 2018

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Vitamin D and the risk of acute allograft rejection following human liver transplantation.

21 January 2018

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Influence of 1,25-dihydroxyvitamin D3 on human leukocyte antigen-DR expression, macrophage infiltration, and graft survival in renal allografts

21 January 2018

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Vitamin D in organ transplantation

21 January 2018

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Ultraviolet radiation and autoimmune disease: insights from epidemiological research

21 January 2018

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Low vitamin D status despite abundant sun exposure

21 January 2018

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Gender-specific association of vitamin D receptor polymorphism combinations with type 1 diabetes mellitus

21 January 2018

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Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes

21 January 2018

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Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in the Dalmatian population.

21 January 2018

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Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

21 January 2018

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Association of vitamin D receptor genotypes with early onset rheumatoid arthritis

21 January 2018

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UVR, vitamin D and three autoimmune diseases--multiple sclerosis, type 1 diabetes, rheumatoid arthritis.

21 January 2018

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Vitamin D endocrine system involvement in autoimmune rheumatic diseases

21 January 2018

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TNF blockade requires 1,25(OH)2D3 to control human Th17-mediated synovial inflammation

21 January 2018

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The evidence for a role of B cells in multiple sclerosis

21 January 2018

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Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis

21 January 2018

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Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis

21 January 2018

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The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis

21 January 2018

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Induction of tolerogenic dendritic cells by vitamin D receptor agonists

21 January 2018

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Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques

21 January 2018

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MC1288, a vitamin D analog, prevents acute graft-versus-host disease in rat bone marrow transplantation

21 January 2018

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Vitamin D receptor gene polymorphism associates with graft-versus-host disease and survival in HLA-matched sibling allogeneic bone marrow transplantation

21 January 2018

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Prevention of chronic allograft rejection by Vitamin D receptor agonists

21 January 2018

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Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.

21 January 2018

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Vitamin D binding protein and asthma severity in children

21 January 2018

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Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study

21 January 2018

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Relationship of vitamin D status to adult lung function and COPD

21 January 2018

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Maternal Vitamin D Status in Pregnancy and Risk of Lower Respiratory Tract Infections, Wheezing, and Asthma in Offspring

21 January 2018

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Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children

21 January 2018

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The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERS.12.57

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28 August 2017

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