Review: Axon pathology in age-related neurodegenerative disorders (Q38050513)

27 August 2017

title

Review: Axon pathology in age-related neurodegenerative disorders (English)

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27 August 2017

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R Adalbert

1

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27 August 2017

M P Coleman

series ordinal

2

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27 August 2017

publication date

1 February 2013

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Neuropathology and Applied Neurobiology

27 August 2017

published in

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27 August 2017

volume

39

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27 August 2017

issue

2

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27 August 2017

page(s)

90-108

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Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies.

27 August 2017

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Alzheimer disease models and human neuropathology: similarities and differences

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The canine as an animal model of human aging and dementia

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Amyloid precursor protein in aged nonhuman primates

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Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease.

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Amyloid beta from axons and dendrites reduces local spine number and plasticity.

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Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development

21 January 2018

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Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex

21 January 2018

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BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology

21 January 2018

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Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment

21 January 2018

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A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis

21 January 2018

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Functional implications of the presenilin dimerization: reconstitution of gamma-secretase activity by assembly of a catalytic site at the dimer interface of two catalytically inactive presenilins

21 January 2018

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Convergence of Presenilin- and Tau-Mediated Pathways on Axonal Trafficking and Neuronal Function

21 January 2018

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Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation

21 January 2018

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Familial Alzheimer disease-linked mutations specifically disrupt Ca2 leak function of presenilin 1

21 January 2018

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The Wnt signaling pathway in development and disease

21 January 2018

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

21 January 2018

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GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner

21 January 2018

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Tau reduction prevents Abeta-induced defects in axonal transport.

21 January 2018

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Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

In vivo structural neuroanatomy of corpus callosum in Alzheimer's disease and mild cognitive impairment using different MRI techniques: a review

21 January 2018

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When, where, and how the corpus callosum changes in MCI and AD: a multimodal MRI study.

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Fiber composition of the human corpus callosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Synaptic degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Traumatic brain injury and Alzheimer's disease: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Traumatic axonal injury: practical issues for diagnosis in medicolegal cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

βA4 amyloid protein deposition in brain after head trauma

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Widespread τ and amyloid-β pathology many years after a single traumatic brain injury in humans.

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig.

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Protein Accumulation in Traumatic Brain Injury

21 January 2018

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https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Controlled Cortical Impact Traumatic Brain Injury in 3xTg-AD Mice Causes Acute Intra-Axonal Amyloid- Accumulation and Independently Accelerates the Development of Tau Abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Distinct Temporal and Anatomical Distributions of Amyloid-β and Tau Abnormalities following Controlled Cortical Impact in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Axon degeneration in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Incidence and remaining lifetime risk of Parkinson disease in advanced age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

alpha-Synuclein promoter confers susceptibility to Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ß.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The parkinsonian mimetic, MPP , specifically impairs mitochondrial transport in dopamine axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Integrating multiple aspects of mitochondrial dynamics in neurons: Age-related differences and dynamic changes in a chronic rotenone model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Role of axonal transport in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Deficits in axonal transport precede ALS symptoms in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Increased Axonal Mitochondrial Mobility Does Not Slow Amyotrophic Lateral Sclerosis (ALS)-like Disease in Mutant SOD1 Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Morphology of axonal transport abnormalities in primate eyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Optic nerve dynein motor protein distribution changes with intraocular pressure elevation in a rat model of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The mechanism of axonal degeneration after perikaryal excitotoxic injury to the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Marked loss of myelinated nerve fibers in the human brain with age

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Effects of age on axon terminals forming axosomatic and axodendritic inhibitory synapses in prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Age changes in myelinated nerve fibers of the cingulate bundle and corpus callosum in the rhesus monkey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Disrupted myelin and axon loss in the anterior commissure of the aged rhesus monkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Qualitative and quantitative morphology of human sural nerve at different ages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

White matter myelin loss in the brains of aged dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Age-associated alterations of the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Age-induced disruption of selective olfactory bulb synaptic circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Aging of the human cerebellum: a stereological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Neurite sprouting and synapse deterioration in the aging Caenorhabditis elegans nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Active zone density is conserved during synaptic growth but impaired in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Dynein dysfunction disrupts intracellular vesicle trafficking bidirectionally and perturbs synaptic vesicle docking via endocytic disturbances a potential mechanism underlying age-dependent impairment of cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Shared resistance to aging and ALS in neuromuscular junctions of specific muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Ageing of substantia nigra in humans: cell loss may be compensated by hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Morphometry of the human substantia nigra in ageing and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Effect of Aging on Tyrosine Hydroxylase Protein Content and the Relative Number of Dopamine Nerve Terminals in Human Caudate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Increased dendritic extent in hippocampal CA1 neurons from aged F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Cellular reorganization in the human retina during normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Spontaneous age-related neurite branching in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Molecular signaling how do axons die?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Late onset distal axonal swelling in YFP-H transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Aging attenuates dynactin-dynein interaction: down-regulation of dynein causes accumulation of endogenous tau and amyloid precursor protein in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Mitochondria as a central sensor for axonal degenerative stimuli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Morphological changes in nerve cells during normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

CNS axons retain their competence for myelination throughout life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Rejuvenation of Regeneration in the Aging Central Nervous System

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Mechanisms of CNS remyelination--the key to therapeutic advances.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Differential effect of aging on axon sprouting and regenerative growth in spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Influence of aging on peripheral nerve function and regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Senescent synapses and hippocampal circuit dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Ageing and Parkinson's disease: substantia nigra regional selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Update on amyloid imaging: from healthy aging to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Neuropathology of older persons without cognitive impairment from two community-based studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

DNA instability in postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Autophagy and aging: the importance of maintaining "clean" cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Taking ageing into account in remyelination-based therapies for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The impact of systemic infection on the progression of neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

The relation between inflammation and neurodegeneration in multiple sclerosis brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Lymphatic drainage of the brain and the pathophysiology of neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Anaerobic function of CNS white matter declines with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Impact of age and retinal degeneration on the light input to circadian brain structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1365-2990.2012.01308.X

10.1111/J.1365-2990.2012.01308.X

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference