Anti-inflammatory therapy in type 1 diabetes (Q38025979)

27 August 2017

title

Anti-inflammatory therapy in type 1 diabetes (English)

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27 August 2017

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Bernd Baumann

1

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27 August 2017

Heba H Salem

series ordinal

2

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27 August 2017

Bernhard O Boehm

series ordinal

3

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27 August 2017

publication date

1 October 2012

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27 August 2017

published in

Current diabetes report

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27 August 2017

volume

12

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27 August 2017

issue

5

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27 August 2017

page(s)

499-509

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The BB/Wor rat and the balance hypothesis of autoimmunity

27 August 2017

cites work

1 reference

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The NOD mouse: a model of immune dysregulation

21 January 2018

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Analysis of islet inflammation in human type 1 diabetes.

21 January 2018

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Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

21 January 2018

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https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

21 January 2018

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Immunopathology of the human pancreas in type-I diabetes

21 January 2018

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https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

21 January 2018

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https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Expression and regulation of chemokines in murine and human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

21 January 2018

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https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-κB, inflammation, and metabolic disease.

21 January 2018

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The IkappaB kinase - a bridge between inflammation and cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S11892-012-0299-Y

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

HLA, NFKB1 and NFKBIA gene polymorphism profile in autoimmune diabetes mellitus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Transcriptional Regulation of Type I Diabetes by NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Increased NF-kappa B activity in B cells and bone marrow-derived dendritic cells from NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

A role for transcription factor NF-kappaB in autoimmunity: possible interactions of genes, sex, and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Distinctions between c-Rel and other NF-kappaB proteins in immunity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-κB function in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

B cell-directed therapies in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Blocking NF- B: An Inflammatory Issue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Role of TNF in pathologies induced by nuclear factor kappaB deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Role of NF-kappa B in the pathogenesis of diabetes and its associated complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

21 January 2018

NF-κB in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Differential regulation of Th1-type and Th2-type cytokine profiles in pancreatic islets of C57BL/6 and BALB/c mice by multiple low doses of streptozotocin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Fermented ginseng protects streptozotocin-induced damage in rat pancreas by inhibiting nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Protection from diabetes development by single-chain antibody-mediated delivery of a NF-κB inhibitor specifically to β-cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

High Pancreatic n-3 Fatty Acids Prevent STZ-Induced Diabetes in Fat-1 Mice: Inflammatory Pathway Inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Effects of Flavonoids and other Polyphenols on Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The microRNA-21−PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Cyclosporin therapy for prevention and cure of IDDM. Epidemiological perspective of benefits and risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

NF-κB signaling pathways regulated by CARMA family of scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The Ca2 -dependent Phosphatase Calcineurin Controls the Formation of the Carma1-Bcl10-Malt1 Complex during T Cell Receptor-induced NF-κB Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

High-Dose Aspirin Is Required to Influence Plasma Fibrin Network Structure in Patients With Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Inhibition of NF-kappa B by sodium salicylate and aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Residual Beta Cell Function in Newly Diagnosed Type 1 Diabetes after Treatment with Atorvastatin: The Randomized DIATOR Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Improved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Glycotoxins in the diet promote diabetes and diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

The role of oxidative stress and NF-kappaB activation in late diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Lipoic acid – biological activity and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Blockade of interleukin 1 in type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11892-012-0299-Y

Effect of Sanguis draconis (a dragon's blood resin) on streptozotocin- and cytokine-induced β-cell damage, in vitro and in vivo

21 January 2018

1 reference

12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

Altered fibrin architecture is associated with hypofibrinolysis and premature coronary atherothrombosis

1 reference

12 December 2020

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review

1 reference

12 December 2020

Molecular mechanisms of treg-mediated T cell suppression

1 reference

12 December 2020

T helper cell subsets in insulin-dependent diabetes

1 reference

12 December 2020

Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

1 reference

12 December 2020

1, 2 di-substituted idopyranose from Vitex negundo L. protects against streptozotocin-induced diabetes by inhibiting nuclear factor-kappa B and inducible nitric oxide synthase expression

1 reference

12 December 2020

Effects of low-dosage simvastatin on rheumatoid arthritis through reduction of Th1/Th2 and CD4/CD8 ratios

1 reference

12 December 2020

Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated Apoptosis

1 reference

12 December 2020

Dendritic cell development and survival require distinct NF-kappaB subunits

1 reference

12 December 2020

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

12 December 2020

Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes

1 reference

12 December 2020

Antioxidant and anti-inflammatory effect of conjugated linolenic acid isomers against streptozotocin-induced diabetes

1 reference

12 December 2020

Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10

1 reference

12 December 2020

Regulation of cytokine production during development of autoimmune diabetes induced with multiple low doses of streptozotocin

1 reference

12 December 2020

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse

1 reference

12 December 2020

The survival of antigen-stimulated T cells requires NFkappaB-mediated inhibition of p73 expression

1 reference

12 December 2020

Prevention of spontaneous and experimentally induced diabetes in mice with zinc sulfate-enriched drinking water is associated with activation and reduction of NF-kappa B and AP-1 in islets, respectively

1 reference

12 December 2020

An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha

1 reference

12 December 2020

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase

1 reference

12 December 2020

Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase

1 reference

12 December 2020

NFkappaB polymorphisms and susceptibility to type 1 diabetes

1 reference

12 December 2020

Understanding type 1 diabetes through genetics: advances and prospects

1 reference

12 December 2020

10.1007/S11892-012-0299-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1045993369

0 references

1 reference