Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology (Q38019307)

27 August 2017

title

Acyl-CoA:diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology (English)

1 reference

27 August 2017

Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology (English)

1 reference

https://api.crossref.org/works/10.1016/J.PLIPRES.2012.06.001

4 January 2025

0 references

0 references

5

Randall J Weselake

1 reference

27 August 2017

3

Richard Lehner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22705711

4 January 2025

author name string

Qin Liu

1

1 reference

27 August 2017

Rodrigo M. P. Siloto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22705711

4 January 2025

Scot J. Stone

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22705711

4 January 2025

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22705711

4 January 2025

publication date

15 June 2012

1 reference

full work available at URL

27 August 2017

https://api.elsevier.com/content/article/PII:S0163782712000380?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.PLIPRES.2012.06.001

https://api.elsevier.com/content/article/PII:S0163782712000380?httpAccept=text/plain

4 January 2025

1 reference

https://api.crossref.org/works/10.1016/J.PLIPRES.2012.06.001

Progress in Lipid Research

4 January 2025

published in

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27 August 2017

volume

51

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27 August 2017

issue

4

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27 August 2017

page(s)

350-377

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Triacylglycerol metabolism

27 August 2017

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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Cloning and characterization of a cDNA encoding diacylglycerol acyltransferase from castor bean.

4 January 2025

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4 January 2025

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Cloning of a cDNA encoding diacylglycerol acyltransferase from Arabidopsis thaliana and its functional expression

4 January 2025

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Cloning and characterization of an acyl-CoA-dependent diacylglycerol acyltransferase 1 (DGAT1) gene from Tropaeolum majus, and a study of the functional motifs of the DGAT protein using site-directed mutagenesis to modify enzyme activity and oil con

4 January 2025

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The olive DGAT2 gene is developmentally regulated and shares overlapping but distinct expression patterns with DGAT1.

4 January 2025

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A leaf-based assay using interchangeable design principles to rapidly assemble multistep recombinant pathways.

4 January 2025

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The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

4 January 2025

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Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells

4 January 2025

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Cloning and molecular characterization of a novel acyl‐CoA:diacylglycerol acyltransferase 1‐like gene (PtDGAT1) from the diatom Phaeodactylum tricornutum

4 January 2025

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Metabolic engineering of hydroxy fatty acid production in plants: RcDGAT2 drives dramatic increases in ricinoleate levels in seed oil.

4 January 2025

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Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phase

4 January 2025

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Type II diacylglycerol acyltransferase from Claviceps purpurea with ricinoleic acid, a hydroxyl fatty acid of industrial importance, as preferred substrate

4 January 2025

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Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases

4 January 2025

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Triacylglycerol synthesis and diacylglycerol acyltransferase activity during skeletal myogenesis

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Characterization of the diacylglycerol acyltransferase activity in the lipid body fraction from an oleaginous fungus

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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A simple method for displaying the hydropathic character of a protein

4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

4 January 2025

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The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

4 January 2025

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4 January 2025

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4 January 2025

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4 January 2025

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A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling

4 January 2025

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Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity.

4 January 2025

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4 January 2025

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The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain

4 January 2025

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4 January 2025

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Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins

4 January 2025

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A di-arginine motif contributes to the ER localization of the type I transmembrane ER oxidoreductase TMX4.

4 January 2025

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4 January 2025

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4 January 2025

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A Conserved Histidine Is Essential for Glycerolipid Acyltransferase Catalysis

4 January 2025

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Seed-specific over-expression of an Arabidopsis cDNA encoding a diacylglycerol acyltransferase enhances seed oil content and seed weight

4 January 2025

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4 January 2025

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Characterization of cDNAs encoding diacylglycerol acyltransferase from cultures of Brassica napus and sucrose-mediated induction of enzyme biosynthesis

4 January 2025

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Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.

4 January 2025

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4 January 2025

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Expression and properties of diacylglycerol acyltransferase from cell-suspension cultures of oilseed rape

4 January 2025

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Acyl-CoA-binding and self-associating properties of a recombinant 13.3 kDa N-terminal fragment of diacylglycerol acyltransferase-1 from oilseed rape

4 January 2025

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An N-terminal fragment of mouse DGAT1 binds different acyl-CoAs with varying affinity

4 January 2025

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Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein

4 January 2025

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Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content

4 January 2025

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A phenylalanine in DGAT is a key determinant of oil content and composition in maize

4 January 2025

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Mutation of F417 but not of L418 or L420 in the lipid binding domain decreases the activity of triacylglycerol hydrolase

4 January 2025

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4 January 2025

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4 January 2025

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Subcellular localization of triacylglycerol synthesis in spinach leaves

4 January 2025

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Pathway for the synthesis of triacylglycerols from monogalactosyldiacylglycerols in ozone-fumigated spinach leaves

4 January 2025

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4 January 2025

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Proteomic profiling of oil bodies isolated from the unicellular green microalga Chlamydomonas reinhardtii: with focus on proteins involved in lipid metabolism

4 January 2025

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Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

4 January 2025

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Ca(2 ) transfer from the ER to mitochondria: when, how and why

4 January 2025

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An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship

4 January 2025

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The adipose organ: morphological perspectives of adipose tissues.

4 January 2025

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Morphometric evaluation of lipid droplet associations with secretory vesicles, mitochondria and other components in the lactating cell

4 January 2025

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Fluorescence resonance energy transfer analysis of mitochondrial:lipid association in the porcine oocyte

4 January 2025

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4 January 2025

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Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein

4 January 2025

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Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies.

4 January 2025

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Characterization of the Drosophila lipid droplet subproteome.

4 January 2025

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The lipid-droplet proteome reveals that droplets are a protein-storage depot.

4 January 2025

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Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

4 January 2025

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Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

4 January 2025

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Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells

4 January 2025

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Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis.

4 January 2025

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A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet

4 January 2025

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4 January 2025

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Global analysis of protein localization in budding yeast

4 January 2025

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The spatial organization of lipid synthesis in the yeast Saccharomyces cerevisiae derived from large scale green fluorescent protein tagging and high resolution microscopy

4 January 2025

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Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae.

4 January 2025

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DGAT and triglyceride synthesis: a new target for obesity treatment?

4 January 2025

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Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models

4 January 2025

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Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis

4 January 2025

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In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens

4 January 2025

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The inhibition of diacylglycerol acyltransferase by terpenoids from Youngia koidzumiana.

4 January 2025

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Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster.

4 January 2025

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In vivo efficacy of acyl CoA: diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia

4 January 2025

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New Polyacetylenes, DGAT inhibitors from the roots of Panax ginseng

4 January 2025

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Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.

4 January 2025

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Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

4 January 2025

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Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus

4 January 2025

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Coenzyme A: diacylglycerol acyltransferase 1 inhibitor ameliorates obesity, liver steatosis, and lipid metabolism abnormality in KKAy mice fed high-fat or high-carbohydrate diets.

4 January 2025

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A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity.

4 January 2025

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Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor

4 January 2025

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Identification and Preliminary Characterization of a Potent, Safe, and Orally Efficacious Inhibitor of Acyl-CoA:Diacylglycerol Acyltransferase 1

4 January 2025

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Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice

4 January 2025

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Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

4 January 2025

224

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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

4 January 2025

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A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice

4 January 2025

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Metabolic control analysis is helpful for informed genetic manipulation of oilseed rape (Brassica napus) to increase seed oil content

4 January 2025

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Expression of Umbelopsis ramanniana DGAT2A in seed increases oil in soybean.

4 January 2025

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Expression of Fungal diacylglycerol acyltransferase2 Genes to Increase Kernel Oil in Maize

4 January 2025

229

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Vernonia DGATs can complement the disrupted oil and protein metabolism in epoxygenase-expressing soybean seeds

4 January 2025

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A distinct DGAT with sn-3 acetyltransferase activity that synthesizes unusual, reduced-viscosity oils in Euonymus and transgenic seeds

4 January 2025

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Directed evolution of acyl-CoA:diacylglycerol acyltransferase: development and characterization of Brassica napus DGAT1 mutagenized libraries

4 January 2025

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TAG, You’re it! Chlamydomonas as a reference organism for understanding algal triacylglycerol accumulation

4 January 2025

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Three acyltransferases and nitrogen-responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas

4 January 2025

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Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase

4 January 2025

236

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Isolation of a gene encoding a 1,2-diacylglycerol-sn-acetyl-CoA acetyltransferase from developing seeds of Euonymus alatus

4 January 2025

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Cloning and functional analysis of two type 1 diacylglycerol acyltransferases from Vernonia galamensis

4 January 2025

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On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme

4 January 2025

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Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells

4 January 2025

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Expression of two human acyl-CoA:diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes

4 January 2025

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Differential expression of diacylglycerol acyltransferase (DGAT) genes in olive tissues

4 January 2025

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The HMMTOP transmembrane topology prediction server

4 January 2025

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Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

4 January 2025

245

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SVMtm: support vector machines to predict transmembrane segments

4 January 2025

246

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SOSUI: classification and secondary structure prediction system for membrane proteins

4 January 2025

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TOPCONS: consensus prediction of membrane protein topology

4 January 2025

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4 January 2025

Identifiers

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27 August 2017

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