Submaximal PPARγ activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders (Q37992099)

26 August 2017

Submaximal PPARγ activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders (English)

1 reference

26 August 2017

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1 reference

1

Pitchai Balakumar

1 reference

26 August 2017

Sonam Kathuria

2

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26 August 2017

language of work or name

English

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publication date

1 August 2012

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26 August 2017

August 2012

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22404217

full work available at URL

26 December 2024

https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1476-5381.2012.01938.x

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https://europepmc.org/articles/PMC3402765

26 December 2024

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https://europepmc.org/articles/PMC3402765?pdf=render

26 December 2024

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https://doi.org/10.1111/j.1476-5381.2012.01938.x

26 December 2024

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open access

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111/j.1476-5381.2012.01938.x

26 December 2024

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10.1111/J.1476-5381.2012.01938.X

Crossref

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https://api.crossref.org/works/10.1111/J.1476-5381.2012.01938.X

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1476-5381.2012.01938.x

26 December 2024

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10.1111/J.1476-5381.2012.01938.X

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DOI

https://api.crossref.org/works/10.1111/J.1476-5381.2012.01938.X

British Journal of Pharmacology

26 December 2024

published in

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26 August 2017

166

1 reference

26 August 2017

7

1 reference

26 August 2017

1981-1992

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Preconditioning the hyperlipidemic myocardium: Fact or fantasy?

26 August 2017

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Guide to Receptors and Channels (GRAC), 5th edition

6 September 2017

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Is targeting eNOS a key mechanistic insight of cardiovascular defensive potentials of statins?

6 September 2017

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Telmisartan prevents VCAM-1 induction and monocytic cell adhesion to endothelium exposed to non-uniform shear stress and TNF-α

6 September 2017

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Interplay between statins and PPARs in improving cardiovascular outcomes: a double‐edged sword?

6 September 2017

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6 September 2017

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6 September 2017

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Endoplasmic Reticulum Ca2 Release Modulates Endothelial Nitric-oxide Synthase via Extracellular Signal-regulated Kinase (ERK) 1/2-mediated Serine 635 Phosphorylation

6 September 2017

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6 September 2017

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PAM-1616, a selective peroxisome proliferator-activated receptor γ modulator with preserved anti-diabetic efficacy and reduced adverse effects

6 September 2017

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Rosiglitazone via upregulation of Akt/eNOS pathways attenuates dysfunction of endothelial progenitor cells, induced by advanced glycation end products

6 September 2017

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6 September 2017

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PAR-1622 is a selective peroxisome proliferator-activated receptor gamma partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention

6 September 2017

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MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema

6 September 2017

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6 September 2017

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6 September 2017

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Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma Activation

6 September 2017

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6 September 2017

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Thiazolidinediones: effects on insulin resistance and the cardiovascular system

6 September 2017

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Cardioprotective effects of curcumin

6 September 2017

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PPAR ligands: are they potential agents for cardiovascular disorders?

6 September 2017

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PPAR dual agonists: are they opening Pandora's Box?

6 September 2017

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6 September 2017

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Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease

6 September 2017

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Peroxisome proliferator-activated receptor-gamma agonists for management and prevention of vascular disease in patients with and without diabetes mellitus

6 September 2017

1 reference

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Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation

6 September 2017

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Targeting Rho and Rho-kinase in the treatment of cardiovascular disease

6 September 2017

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6 September 2017

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Modulation of the L-arginine/nitric oxide signalling pathway in vascular endothelial cells

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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28 September 2017

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28 September 2017

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Thiazolidinediones in the treatment of insulin resistance and type II diabetes

28 September 2017

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Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice.

28 September 2017

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Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice

23 June 2018

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Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase

23 June 2018

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PPAR gamma partial agonist, KR-62776, inhibits adipocyte differentiation via activation of ERK.

23 June 2018

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Telmisartan decreases plasma levels of asymmetrical dimethyl-L-arginine and improves lipid and glucose metabolism and vascular function

23 June 2018

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AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633

23 June 2018

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AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats

23 June 2018

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A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.

23 June 2018

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Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2.

23 June 2018

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Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex

23 June 2018

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Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

23 June 2018

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cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide

23 June 2018

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Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cells

23 June 2018

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Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions

23 June 2018

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Red wine: a source of potent ligands for peroxisome proliferator-activated receptor γ.

23 June 2018

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Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity

31 August 2018

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31 August 2018

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Effect of rosiglitazone in sodium arsenite-induced experimental vascular endothelial dysfunction

31 August 2018

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Peroxisome proliferator-activated receptor-gamma(PPARgamma) agonist improves coronary artery endothelial function in diabetic patients with coronary artery disease

31 August 2018

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Vascular insulin resistance in prehypertensive rats: role of PI3-kinase/Akt/eNOS signaling

31 August 2018

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Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic acid (MK-0533): a novel selective peroxisome proliferator-activated receptor gamma modulator for the treatment of type 2 diabetes mell

31 August 2018

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Up-regulating PPAR-γ expression and NO concentration, and down-regulating PAI-1 concentration in a rabbit atherosclerotic model: the possible antiatherogenic and antithrombotic effects of atorvastatin

31 August 2018

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Benfotiamine attenuates nicotine and uric acid-induced vascular endothelial dysfunction in the rat.

31 August 2018

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Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats

31 August 2018

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Effects of telmisartan, a unique angiotensin receptor blocker with selective peroxisome proliferator-activated receptor-gamma-modulating activity, on nitric oxide bioavailability and atherosclerotic change

31 August 2018

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Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts

31 August 2018

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Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice.

31 August 2018

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Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms

31 August 2018

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Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property

31 August 2018

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Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Red wine polyphenols prevent cardiovascular alterations in L-NAME-induced hypertension.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-indepen

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Thiazolidinediones in type 2 diabetes. Role of peroxisome proliferator-activated receptor gamma (PPARgamma)

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Wine polyphenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Endothelial dysfunction in hypertension

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402765

Pioglitazone ameliorates endothelial dysfunction and restores ischemia-induced angiogenesis in diabetic mice

1 October 2018

1 reference

12 December 2020

Telmisartan provides protection against development of impaired vasodilation independently of metabolic effects in SHRSP.Z-Leprfa/IzmDmcr rats with metabolic syndrome

1 reference

12 December 2020

Telmisartan downregulates angiotensin II type 1 receptor through activation of peroxisome proliferator-activated receptor gamma

1 reference

12 December 2020

AMP-activated protein kinase phosphorylation of endothelial NO synthase

1 reference

12 December 2020

[Telmisartan in monotherapy of essential hypertension in young men--time of drug administration and 24-hours blood pressure and heart rate]

1 reference

12 December 2020

Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats

1 reference

12 December 2020

10.1111/J.1476-5381.2012.01938.X

Identifiers

DOI

1 reference

26 August 2017

1 reference

26 August 2017

1 reference