Phosphoinositide Phosphatases: Just as Important as the Kinases (Q37992012)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403078 AND SRC:MED&resulttype=core&format=json

25 January 2020

title

Phosphoinositide phosphatases: just as important as the kinases (English)

1 reference

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25 January 2020

Phosphoinositide Phosphatases: Just as Important as the Kinases (English)

1 reference

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26 December 2024

2

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25 January 2020

author name string

Jelena Becanovic

4

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25 January 2020

Jennifer M. Dyson

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26 December 2024

Elizabeth M. Davies

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26 December 2024

Christina A. Mitchell

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26 December 2024

language of work or name

English

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National Center for Biotechnology Information

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26 December 2024

publication date

1 January 2012

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25 January 2020

2012

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22403078

full work available at URL

26 December 2024

http://link.springer.com/content/pdf/10.1007/978-94-007-3012-0_7.pdf

1 reference

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Sub-cellular biochemistry

26 December 2024

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403078 AND SRC:MED&resulttype=core&format=json

25 January 2020

volume

58

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25 January 2020

page(s)

215-279

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Integrative genomic profiling of human prostate cancer

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Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

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X-inactivation analysis of embryonic lethality in Ocrl wt/-; Inpp5b-/- mice

26 December 2024

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Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits inositide trisphosphate accumulation in hypothalamus and regulates food intake and body weight

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26 December 2024

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Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.

26 December 2024

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Dent-2 disease: a mild variant of Lowe syndrome

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Protein-truncating mutations in ASPM cause variable reduction in brain size

26 December 2024

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Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase

26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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The two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytes

26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity

26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network

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The lipid phosphatase SHIP2 controls insulin sensitivity

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26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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26 December 2024

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Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation

26 December 2024

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HYPERCALCURIC RICKETS ASSOCIATED WITH RENAL TUBULAR DAMAGE.

26 December 2024

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Three SAC1‐like genes show overlapping patterns of expression in Arabidopsis but are remarkably silent during embryo development

26 December 2024

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T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

26 December 2024

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Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels

26 December 2024

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The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover

26 December 2024

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The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

26 December 2024

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26 December 2024

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CD28 stimulates tyrosine phosphorylation, cellular redistribution and catalytic activity of the inositol lipid 5-phosphatase SHIP

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Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

26 December 2024

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Pheromone-regulated Genes Required for Yeast Mating Differentiation

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A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

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Large-scale identification of disease genes involved in acute myeloid leukemia

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26 December 2024

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Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p

26 December 2024

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Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

26 December 2024

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Molecular cytogenetic analysis of consistent abnormalities at 8q12-q22 in breast cancer.

26 December 2024

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Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.

26 December 2024

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Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a

26 December 2024

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Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology

26 December 2024

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

26 December 2024

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Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)

26 December 2024

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Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice

26 December 2024

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Regulation of endogenous SH2 domain-containing inositol 5-phosphatase (SHIP2) in 3T3-L1 and human preadipocytes

26 December 2024

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Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity

26 December 2024

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A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa

26 December 2024

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Up-regulation of the T cell quiescence factor KLF2 in a leukaemic T-cell line after expression of the inositol 5'-phosphatase SHIP-1.

26 December 2024

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Lowe's syndrome: identification of carriers by lens examination

26 December 2024

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Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.

26 December 2024

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1 reference

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Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling

26 December 2024

113

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses

26 December 2024

114

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets

26 December 2024

115

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels

26 December 2024

116

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The role of SHIP1 in T-lymphocyte life and death

26 December 2024

117

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons

26 December 2024

118

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Normalization of prandial blood glucose and improvement of glucose tolerance by liver-specific inhibition of SH2 domain containing inositol phosphatase 2 (SHIP2) in diabetic KKAy mice: SHIP2 inhibition causes insulin-mimetic effects on glycogen metab

26 December 2024

119

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Reg IV: a promising marker of hormone refractory metastatic prostate cancer

26 December 2024

121

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.

26 December 2024

122

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.

26 December 2024

123

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

26 December 2024

124

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...

26 December 2024

125

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP1 is a repressor of mast cell hyperplasia, cytokine production, and allergic inflammation in vivo.

26 December 2024

126

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Direct interaction of the 170 kDa isoform of synaptojanin 1 with clathrin and with the clathrin adaptor AP-2

26 December 2024

127

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

26 December 2024

Role of SHIP in cancer

128

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Mutations in synaptojanin disrupt synaptic vesicle recycling

26 December 2024

129

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Where Proteins and Lipids Meet

26 December 2024

131

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Targeted disruption ofSHIPleads to hemopoietic perturbations, lung pathology, and a shortened life span

26 December 2024

132

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Disrupted sperm function and fertilin beta processing in mice deficient in the inositol polyphosphate 5-phosphatase Inpp5b

26 December 2024

134

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism

26 December 2024

135

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration

26 December 2024

136

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits

26 December 2024

137

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions

26 December 2024

138

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

26 December 2024

139

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Dent Disease with mutations in OCRL1

26 December 2024

140

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of Fc R-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3 mediated phagocytosis by differential recruitment of these 5-phosphatases to the p

26 December 2024

141

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

26 December 2024

142

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

26 December 2024

143

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The role of SHIP in mast cell degranulation and IgE-induced mast cell survival

26 December 2024

144

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Sac phosphatase domain proteins.

26 December 2024

145

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Suppression of hepatitis B viral gene expression by phosphoinositide 5-phosphatase SKIP

26 December 2024

146

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases

26 December 2024

147

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes

26 December 2024

148

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation

26 December 2024

150

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification and characterization of a novel inositol polyphosphate 5-phosphatase

26 December 2024

151

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Increased insulin action in SKIP heterozygous knockout mice

26 December 2024

152

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes

26 December 2024

153

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder

26 December 2024

154

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

MicroRNA gene expression deregulation in human breast cancer

26 December 2024

155

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

microRNA-205 regulates HER3 in human breast cancer

26 December 2024

156

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1

26 December 2024

157

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Association of SH-2 containing inositol 5'-phosphatase 2 gene polymorphisms and hyperglycemia

26 December 2024

158

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcgammaRIIB and is mandatory for negative regulation of B cell activation

26 December 2024

159

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane

26 December 2024

160

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.

26 December 2024

161

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase

26 December 2024

162

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse

26 December 2024

163

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Localization of the 75-kDa inositol polyphosphate-5-phosphatase (INPP5B) to human chromosome band 1p34.

26 December 2024

164

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Mapping of the 75-kDa inositol polyphosphate-5-phosphatase (Inpp5b) to distal mouse chromosome 4 and its exclusion as a candidate gene for dysgenetic lens

26 December 2024

165

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice

26 December 2024

166

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Toxicology of antisense therapeutics

26 December 2024

167

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Properties of type II inositol polyphosphate 5-phosphatase

26 December 2024

168

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Evidence for a positive role of SHIP in the BCR-ABL-mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia

26 December 2024

169

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2.

26 December 2024

170

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants

26 December 2024

171

1 reference

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Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

26 December 2024

172

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice

26 December 2024

173

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome

26 December 2024

174

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Downstream of tyrosine kinases-1 and Src homology 2-containing inositol 5'-phosphatase are required for regulation of CD4 CD25 T cell development

26 December 2024

175

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake

26 December 2024

176

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Lissencephaly and the molecular basis of neuronal migration

26 December 2024

177

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Oculocerebrorenal syndrome of Lowe: Three mutations in theOCRL1 gene derived from three patients with different phenotypes

26 December 2024

178

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor

26 December 2024

180

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase

26 December 2024

181

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt.

26 December 2024

182

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane.

26 December 2024

183

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Pathogenic factors of glucose intolerance in obese Japanese adolescents with type 2 diabetes

26 December 2024

184

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network

26 December 2024

185

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane

26 December 2024

186

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement

26 December 2024

187

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis

26 December 2024

188

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Genetic analysis of primary microcephaly in Indian families: novel ASPM mutations

26 December 2024

189

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis

26 December 2024

190

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Sphingosine-1-phosphate receptor S1P1 is regulated by direct interactions with P-Rex1, a Rac guanine nucleotide exchange factor

26 December 2024

194

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses

26 December 2024

195

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans

26 December 2024

196

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells.

26 December 2024

197

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The effect of missense mutations in the RhoGAP-homology domain on ocrl1 function

26 December 2024

198

1 reference

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Spectrum of mutations in the OCRL1 gene in the Lowe oculocerebrorenal syndrome

26 December 2024

199

1 reference

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APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

26 December 2024

200

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Multiple Cytokines Stimulate the Binding of a Common 145-Kilodalton Protein to Shc at the Grb2 Recognition Site of Shc

26 December 2024

201

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

26 December 2024

202

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

26 December 2024

204

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals

26 December 2024

205

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Functional studies of the mammalian Sac1 phosphoinositide phosphatase

26 December 2024

206

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Inactivation of SHIP1 in T-cell acute lymphoblastic leukemia due to mutation and extensive alternative splicing

26 December 2024

207

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Structure and function of the Lowe syndrome protein OCRL1.

26 December 2024

208

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemia

26 December 2024

210

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Zhongguo shi yan xue ye xue za zhi

26 December 2024

211

12

420

JM Luo

2004

1 reference

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PI(3,4,5)P3 and PI(3,4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI(3,4)P2 levels determine PKB activity.

26 December 2024

212

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production

26 December 2024

213

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

MicroRNA‐205–directed transcriptional activation of tumor suppressor genes in prostate cancer

26 December 2024

214

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin 2, a novel Rac1 effector that regulates clathrin-mediated endocytosis

26 December 2024

215

1 reference

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SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34

26 December 2024

216

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

26 December 2024

217

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals

26 December 2024

218

1 reference

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A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.

26 December 2024

219

1 reference

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A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism

26 December 2024

220

1 reference

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Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension

26 December 2024

221

1 reference

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Multivariate analysis of male reproductive function in Inpp5b-/- mice reveals heterogeneity in defects in fertility, sperm-egg membrane interaction and proteolytic cleavage of sperm ADAMs.

26 December 2024

222

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man

26 December 2024

223

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling

26 December 2024

224

1 reference

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Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase

26 December 2024

225

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Distinct membrane and cytosolic forms of inositol polyphosphate 5-phosphatase II. Efficient membrane localization requires two discrete domains

26 December 2024

226

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity

26 December 2024

227

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding

26 December 2024

228

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

A presynaptic inositol-5-phosphatase

26 December 2024

229

1 reference

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Intrastriatal AP5 differentially affects behaviors induced by local infusions of D1 vs. D2 dopamine agonists

26 December 2024

230

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

26 December 2024

231

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

26 December 2024

232

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase

26 December 2024

233

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles

26 December 2024

235

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.

26 December 2024

236

1 reference

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The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol

26 December 2024

237

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Mechanisms of insulin action on sympathetic nerve activity

26 December 2024

238

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Distribution of the src-homology-2-domain-containing inositol 5-phosphatase SHIP-2 in both non-haemopoietic and haemopoietic cells and possible involvement of SHIP-2 in negative signalling of B-cells

26 December 2024

239

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors

26 December 2024

240

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

26 December 2024

241

1 reference

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High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization

26 December 2024

242

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP-deficient mice provide insights into the regulation of dendritic cell development and function

26 December 2024

243

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin 2, a Novel Synaptojanin Isoform with a Distinct Targeting Domain and Expression Pattern

26 December 2024

244

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

26 December 2024

245

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals

26 December 2024

246

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Localization of the Schwartz-Jampel syndrome (SJS) locus to chromosome 1p34-p36.1 by homozygosity mapping.

26 December 2024

247

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells

26 December 2024

248

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formation

26 December 2024

249

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

26 December 2024

250

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

26 December 2024

251

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-Phosphatase

26 December 2024

254

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family

26 December 2024

255

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase

26 December 2024

256

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice

26 December 2024

258

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Inositol phosphatase SHIP1 is a primary target of miR-155

26 December 2024

259

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.

26 December 2024

260

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

26 December 2024

261

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Nephropathy in type 1 diabetes: a manifestation of insulin resistance and multiple genetic susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes Complication Study

26 December 2024

262

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter

26 December 2024

264

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

26 December 2024

265

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

26 December 2024

266

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Insulin Resistance and Microalbuminuria: A Cross-Sectional, Case-Control Study of 158 Patients With Type 2 Diabetes and Different Degrees of Urinary Albumin Excretion

26 December 2024

267

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP2 interaction with the cytoskeletal protein Vinexin

26 December 2024

268

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2

26 December 2024

269

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas

26 December 2024

270

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

26 December 2024

271

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.

26 December 2024

272

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification of a Second SH2-Domain-Containing Protein Closely Related to the Phosphatidylinositol Polyphosphate 5-Phosphatase SHIP

26 December 2024

273

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux

26 December 2024

274

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

A novel domain suggests a ciliary function for ASPM, a brain size determining gene

26 December 2024

275

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Normal cognitive functions in joubert syndrome.

26 December 2024

276

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading

26 December 2024

277

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

26 December 2024

279

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling

26 December 2024

280

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway

26 December 2024

281

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

A molecular signature of metastasis in primary solid tumors

26 December 2024

282

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties

26 December 2024

283

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Role of Src homology 2-containing-inositol 5'-phosphatase (SHIP) in mast cells and macrophages

26 December 2024

284

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP represses the generation of alternatively activated macrophages

26 December 2024

285

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The SH3p4/Sh3p8/SH3p13 protein family: Binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain

26 December 2024

286

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy

26 December 2024

287

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Human Phosphatidylinositol Phosphatase SAC1 Interacts with the Coatomer I Complex

26 December 2024

288

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Role of SHIP-1 in the adaptive immune responses to aeroallergen in the airway

26 December 2024

290

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Carrier assessment in families with lowe oculocerebrorenal syndrome: novel mutations in the OCRL1 gene and correlation of direct DNA diagnosis with ocular examination.

26 December 2024

291

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-REX2, a novel PI-3-kinase sensitive Rac exchange factor.

26 December 2024

292

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific Phosphatase

26 December 2024

293

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.

26 December 2024

294

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin 2 functions at an early step of clathrin-mediated endocytosis

26 December 2024

295

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Patterned neuroprotection in the Inpp4a(wbl) mutant mouse cerebellum correlates with the expression of Eaat4

26 December 2024

296

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays

26 December 2024

297

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Mammalian phosphoinositide kinases and phosphatases

26 December 2024

298

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death

26 December 2024

299

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes

26 December 2024

300

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells

26 December 2024

301

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

BCR/ABL directly inhibits expression of SHIP, an SH2-containing polyinositol-5-phosphatase involved in the regulation of hematopoiesis

26 December 2024

302

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex

26 December 2024

304

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

26 December 2024

305

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation

26 December 2024

306

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase

26 December 2024

307

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Endophilin Is Required for Synaptic Vesicle Endocytosis by Localizing Synaptojanin

26 December 2024

308

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Molecular cloning of multiple isoforms of synaptojanin 2 and assignment of the gene to mouse chromosome 17A2-3.1.

26 December 2024

309

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

OCRL1 mutations in patients with Dent disease phenotype in Japan

26 December 2024

310

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Loss of Inositol Polyphosphate 5-Phosphatase Is an Early Event in Development of Cutaneous Squamous Cell Carcinoma

26 December 2024

311

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

26 December 2024

312

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma

26 December 2024

313

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The gene for schnyder's crystalline corneal dystrophy maps to human chromosome 1p34.1-p36

26 December 2024

314

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Biochemical characterization of the type I inositol polyphosphate 4-phosphatase C2 domain

26 December 2024

315

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

26 December 2024

316

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

OCRL1 mutations in Dent 2 patients suggest a mechanism for phenotypic variability

26 December 2024

317

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

26 December 2024

318

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice

26 December 2024

319

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

26 December 2024

320

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model

26 December 2024

322

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

CD4 CD25 regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity

26 December 2024

323

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae

26 December 2024

324

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Genetic polymorphisms and treatment response in advanced non-small cell lung cancer.

26 December 2024

325

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

DNA copy number alterations in prostate cancers: a combined analysis of published CGH studies

26 December 2024

326

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2.

26 December 2024

327

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

26 December 2024

328

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling

26 December 2024

329

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase

26 December 2024

330

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

LL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2.

26 December 2024

331

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

26 December 2024

333

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Novel genes associated with malignant melanoma but not benign melanocytic lesions

26 December 2024

334

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Essential role of p38gamma in K-Ras transformation independent of phosphorylation

26 December 2024

335

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses

26 December 2024

336

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells

26 December 2024

337

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The nonmotile ciliopathies

26 December 2024

339

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Two sides to cilia in cancer

26 December 2024

340

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase

26 December 2024

341

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells.

26 December 2024

342

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity

26 December 2024

343

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase

26 December 2024

345

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein

26 December 2024

346

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Increased levels of plasma lysosomal enzymes in patients with Lowe syndrome

26 December 2024

347

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases

26 December 2024

348

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein betagamma subunits and PKA.

26 December 2024

349

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Novel OCRL1 mutations in patients with the phenotype of Dent disease.

26 December 2024

350

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The zebrafish nrc mutant reveals a role for the polyphosphoinositide phosphatase synaptojanin 1 in cone photoreceptor ribbon anchoring.

26 December 2024

351

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Gene expression profiling predicts clinical outcome of breast cancer

26 December 2024

352

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling

26 December 2024

353

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating

26 December 2024

354

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

26 December 2024

355

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1

26 December 2024

356

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

26 December 2024

357

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Influence of SHIP on the NK Repertoire and Allogeneic Bone Marrow Transplantation

26 December 2024

358

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesis

26 December 2024

359

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-Rex1 - a multidomain protein that regulates neurite differentiation

26 December 2024

360

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The Sac1 lipid phosphatase regulates cell shape change and the JNK cascade during dorsal closure in Drosophila

26 December 2024

361

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

26 December 2024

362

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

P-Rex1 regulates neutrophil function

26 December 2024

363

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Predicting the clinical status of human breast cancer by using gene expression profiles

26 December 2024

364

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis

26 December 2024

365

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.

26 December 2024

366

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway

26 December 2024

367

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

26 December 2024

369

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Laser microdissection and microarray analysis of breast tumors reveal ER-alpha related genes and pathways

26 December 2024

370

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Role of lipid metabolism in smoothened derepression in hedgehog signaling

26 December 2024

371

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

26 December 2024

373

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1

26 December 2024

374

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

cDNA Microarray Analysis of Gene Expression Profiles Associated with Cervical Cancer

26 December 2024

375

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

Involvement of a Rac activator,P-Rex1, in neurotrophin-derived signaling and neuronal migration

26 December 2024

376

1 reference

https://api.crossref.org/works/10.1007/978-94-007-3012-0_7

MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia

26 December 2024

377

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