WNK3 is a putative chloride-sensing kinase. (Q37969554)

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18 January 2020

title

WNK3 is a putative chloride-sensing kinase (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179001 AND SRC:MED&resulttype=core&format=json

18 January 2020

author

Diana Pacheco-Alvarez

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179001 AND SRC:MED&resulttype=core&format=json

18 January 2020

Gerardo Gamba

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179001 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Diana Pacheco-Alvarez

1

1 reference

26 August 2017

Gerardo Gamba

2

1 reference

26 August 2017

publication date

16 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179001 AND SRC:MED&resulttype=core&format=json

Cellular Physiology and Biochemistry

18 January 2020

published in

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18 January 2020

volume

28

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18 January 2020

issue

6

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18 January 2020

page(s)

1123-1134

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WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

18 January 2020

cites work

1 reference

Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension

21 January 2018

1 reference

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms

21 January 2018

1 reference

Human hypertension caused by mutations in WNK kinases

21 January 2018

1 reference

Hypercalciuria in familial hyperkalemia and hypertension accompanies hyperkalemia and precedes hypertension: description of a large family with the Q565E WNK4 mutation

21 January 2018

1 reference

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study

21 January 2018

1 reference

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

21 January 2018

1 reference

Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay

21 January 2018

1 reference

Three novel missense mutations of WNK4, a kinase mutated in inherited hypertension, in Japanese hypertensives: implication of clinical phenotypes

21 January 2018

1 reference

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

1 reference

WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells

21 January 2018

1 reference

WNK kinases regulate thiazide-sensitive Na-Cl cotransport

21 January 2018

1 reference

Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved

21 January 2018

1 reference

WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction

21 January 2018

1 reference

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform

21 January 2018

1 reference

WNK1 activates SGK1 to regulate the epithelial sodium channel.

21 January 2018

1 reference

WNK4 regulates activity of the epithelial Na channel in vitro and in vivo.

21 January 2018

1 reference

WNK4 regulates the balance between renal NaCl reabsorption and K secretion

21 January 2018

1 reference

WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4.

21 January 2018

1 reference

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension

21 January 2018

1 reference

Overexpression of human WNK1 increases paracellular chloride permeability and phosphorylation of claudin-4 in MDCKII cells

21 January 2018

1 reference

Molecular physiology of the WNK kinases.

21 January 2018

1 reference

The thiazide-sensitive Na -Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs

21 January 2018

1 reference

The WNKs: atypical protein kinases with pleiotropic actions.

21 January 2018

1 reference

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters

21 January 2018

1 reference

Cloning, genomic organization, alternative splicing and expression analysis of the human gene WNK3 (PRKWNK3).

21 January 2018

1 reference

WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na -Cl- cotransporter

21 January 2018

1 reference

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation

21 January 2018

1 reference

Properties of WNK1 and implications for other family members

21 January 2018

1 reference

Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress

21 January 2018

1 reference

WNK lies upstream of kinases involved in regulation of ion transporters

21 January 2018

1 reference

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

21 January 2018

1 reference

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

21 January 2018

1 reference

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

21 January 2018

1 reference

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)

21 January 2018

1 reference

Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.

21 January 2018

1 reference

Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family

21 January 2018

1 reference

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

21 January 2018

1 reference

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family

21 January 2018

1 reference

Functional comparison of the K -Cl- cotransporters KCC1 and KCC4.

21 January 2018

1 reference

NH2-terminal heterogeneity in the KCC3 K -Cl- cotransporter

21 January 2018

1 reference

Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter

21 January 2018

1 reference

Regulation of Na-K-2Cl cotransport by phosphorylation and protein-protein interactions

21 January 2018

1 reference

A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.

21 January 2018

1 reference

Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2).

21 January 2018

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The Na :Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

21 January 2018

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Phosphoregulation of K( )-Cl(-) cotransporter 4 during changes in intracellular Cl(-) and cell volume

21 January 2018

1 reference

PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)

21 January 2018

1 reference

Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

21 January 2018

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Activation of the thiazide-sensitive Na -Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

21 January 2018

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Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways

21 January 2018

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Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule

21 January 2018

1 reference

Sites of regulated phosphorylation that control K-Cl cotransporter activity

21 January 2018

1 reference

Regulation of K-Cl cotransport: from function to genes

21 January 2018

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WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters

21 January 2018

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WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

21 January 2018

1 reference

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.

21 January 2018

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The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex

21 January 2018

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WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

21 January 2018

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Renal and brain isoforms of WNK3 have opposite effects on NCCT expression

21 January 2018

1 reference

21 January 2018

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Roles of the cation-chloride cotransporters in neurological disease.

21 January 2018

1 reference

Electroneutral cation-chloride cotransporters in the central nervous system

21 January 2018

1 reference

Cation-chloride co-transporters in neuronal communication, development and trauma

21 January 2018

1 reference

Cation-chloride cotransporters and neuronal function

21 January 2018

1 reference

With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume

21 January 2018

1 reference

WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K channel ROMK1 (Kir1.1).

21 January 2018

1 reference

WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway

21 January 2018

1 reference

SLC26A9 is a Cl(-) channel regulated by the WNK kinases

21 January 2018

1 reference

The activity of the thiazide-sensitive Na( )-Cl(-) cotransporter is regulated by protein phosphatase PP4.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000335848

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22179001 AND SRC:MED&resulttype=core&format=json

18 January 2020

1 reference