Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects (Q37959379)

25 August 2017

title

Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects (English)

1 reference

25 August 2017

2

Jose M. López-Novoa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22105921

18 December 2024

author name string

Francisco J. López-Hernández

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22105921

18 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22105921

18 December 2024

publication date

22 November 2011

1 reference

full work available at URL

25 August 2017

http://link.springer.com/content/pdf/10.1007/s00441-011-1275-6.pdf

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

http://link.springer.com/article/10.1007/s00441-011-1275-6/fulltext.html

18 December 2024

file format

HyperText Markup Language

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

http://link.springer.com/content/pdf/10.1007/s00441-011-1275-6

18 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

18 December 2024

published in

Cell and Tissue Research

1 reference

25 August 2017

volume

347

1 reference

25 August 2017

issue

1

1 reference

25 August 2017

page(s)

141-154

1 reference

Cellular basis of diabetic nephropathy: V. Endoglin expression levels and diabetic nephropathy risk in patients with Type 1 diabetes

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Angiotensin II induces apoptosis in renal proximal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta in kidney fibrosis: a target for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta in renal injury and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Gap junctional communication in tissue inflammation and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Role of growth factors in diabetic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Pathogenesis of glomerular damage in glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGFβ enforces activation of eukaryotic elongation factor‐2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Healthcare systems and end-stage renal disease (ESRD) therapies--an international review: costs and reimbursement/funding of ESRD therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Angiotensin II induces apoptosis in rat glomerular epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The mitogen-activated protein kinase Erk5 mediates human mesangial cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Molecular basis of renal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The glomerulus--a view from the inside--the endothelial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

An integrative view on the role of TGF-beta in the progressive tubular deletion associated with chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Fibroblast activation and myofibroblast generation in obstructive nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Functional symbiosis between endothelium and epithelial cells in glomeruli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Fibrogenesis of parenchymal organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta and glomerulonephritis: anti-inflammatory versus prosclerotic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta receptor function in the endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Regulation of immune responses by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The physiological role of endoglin in the cardiovascular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Common pathophysiological mechanisms of chronic kidney disease: therapeutic perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Involvement of small Ras GTPases and their effectors in chronic renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The transforming growth factor-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Tubulointerstitial changes as a major determinant in the progression of renal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Glomerular permeability: a never-ending saga

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta: regulation of extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta1 induces COX-2 expression and PGE2 synthesis through MAPK and PI3K pathways in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Up-regulation of endoglin, a TGF-beta-binding protein, in rats with experimental renal fibrosis induced by renal mass reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Activation of Erk1/2 and Akt following unilateral ureteral obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Apoptosis in podocytes induced by TGF-beta and Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The mesangial cell revisited: no cell is an island

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta signal transduction in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Mesangial cells initiate compensatory tubular cell hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

New insights into mechanisms of fibrosis in immune renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Role of TGF-beta in the progression of renal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The TGF-beta paradox in human cancer: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The pathogenesis of progressive renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta and epithelial-to-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Glomerular morphometry in childhood reflux nephropathy, emphasizing the capillary changes

18 December 2024

2

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Altering expression of alpha3beta1 integrin on podocytes of human and rats with diabetes

18 December 2024

10

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes

18 December 2024

12

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: role of the p38 MAPK pathway

18 December 2024

15

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Mechanical strain of glomerular mesangial cells in the pathogenesis of glomerulosclerosis: clinical implications

18 December 2024

17

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes

18 December 2024

19

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Expression of endoglin in human mesangial cells: modulation of extracellular matrix synthesis

18 December 2024

23

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Cholesterol, macrophages, and gene expression of TGF-beta 1 and fibronectin during nephrosis

18 December 2024

24

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation

18 December 2024

26

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent

18 December 2024

40

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression

18 December 2024

41

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Potential Role of TGF-β in Diabetic Nephropathy

18 December 2024

43

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Transforming growth factor beta 2 stimulates acute and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells

18 December 2024

45

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Role of mitogen-activated protein kinases as downstream effectors of transforming growth factor-beta in mesangial cells

18 December 2024

48

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Expression of connective tissue growth factor in human renal fibrosis

18 December 2024

50

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation

18 December 2024

59

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Controlling TGF-β signaling

18 December 2024

71

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The effect of transforming growth factor beta 1 on mesangial cell fibronectin synthesis: increased incorporation into the extracellular matrix and reduced pI but no effect on alternative splicing

18 December 2024

72

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TNF-alpha neutralization decreases nuclear factor-kappaB activation and apoptosis during renal obstruction

18 December 2024

73

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling

18 December 2024

74

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The MCP-1/CCR2 axis in podocytes is involved in apoptosis induced by diabetic conditions

18 December 2024

77

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Progressive renal disease: fibroblasts, extracellular matrix, and integrins

18 December 2024

80

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

The impact of experimental diabetes mellitus in rats on glomerular capillary number and sizes

18 December 2024

81

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Regulation of human mesangial cell collagen expression by transforming growth factor-beta1

18 December 2024

83

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Endoglin expression in human and rat mesangial cells and its upregulation by TGF-beta1

18 December 2024

89

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Endoglin upregulation during experimental renal interstitial fibrosis in mice

18 December 2024

92

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors

18 December 2024

94

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Congenital nephrotic syndrome in mice lacking CD2-associated protein

18 December 2024

101

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Synaptopodin expression in idiopathic nephrotic syndrome of childhood

18 December 2024

104

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Glomerular cell number in normal subjects and in type 1 diabetic patients

18 December 2024

105

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Connective tissue growth factor and regulation of the mesangial cell cycle: role in cellular hypertrophy

18 December 2024

113

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy

18 December 2024

115

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

Link between Angiotensin II and TGF-β in the Kidney

18 December 2024

118

1 reference

https://api.crossref.org/works/10.1007/S00441-011-1275-6

18 December 2024

Identifiers

1 reference

25 August 2017

1 reference