Molecular mechanisms of endolysosomal Ca2 signalling in health and disease (Q37944859)

25 August 2017

title

Molecular mechanisms of endolysosomal Ca2 signalling in health and disease (English)

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25 August 2017

Frances M Platt

2

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Antony Giuseppe Galione

object named as

Antony Galione

series ordinal

4

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author name string

Anthony J Morgan

series ordinal

1

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25 August 2017

Emyr Lloyd-Evans

series ordinal

3

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25 August 2017

language of work or name

English

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publication date

1 November 2011

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25 August 2017

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25 August 2017

volume

439

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25 August 2017

issue

3

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25 August 2017

page(s)

349-374

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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

25 August 2017

cites work

1 reference

The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2 ) release channels

21 January 2018

1 reference

Acidic calcium stores open for business: expanding the potential for intracellular Ca2 signaling

21 January 2018

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Endolysosomal calcium regulation and disease

21 January 2018

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Sea urchin eggs in the acid reign

21 January 2018

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Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.

21 January 2018

1 reference

Second messenger signaling: multiple receptors for NAADP.

21 January 2018

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NAADP mobilizes Ca(2 ) from reserve granules, lysosome-related organelles, in sea urchin eggs

21 January 2018

1 reference

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

21 January 2018

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Metchnikoff and the phagocytosis theory

21 January 2018

1 reference

21 January 2018

Functions of lysosomes

1 reference

Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase

21 January 2018

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alpha-Glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease).

21 January 2018

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Lysosome-related organelles

21 January 2018

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21 January 2018

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What's special about secretory lysosomes?

21 January 2018

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Plasma membrane repair is mediated by Ca(2 )-regulated exocytosis of lysosomes

21 January 2018

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Neuraminidase 1 is a negative regulator of lysosomal exocytosis

21 January 2018

1 reference

Sorting of lysosomal proteins

21 January 2018

1 reference

LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase

21 January 2018

1 reference

Green fluorescent protein as a noninvasive intracellular pH indicator

21 January 2018

1 reference

Bcl-2 decreases the free Ca2 concentration within the endoplasmic reticulum

21 January 2018

1 reference

Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release.

21 January 2018

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Regulation of organelle acidity

21 January 2018

1 reference

Chloride concentration in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidification

21 January 2018

1 reference

A cation counterflux supports lysosomal acidification

21 January 2018

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Theoretical considerations on the role of membrane potential in the regulation of endosomal pH

21 January 2018

1 reference

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

21 January 2018

1 reference

Structure and regulation of the vacuolar ATPases

21 January 2018

1 reference

Function, structure and regulation of the vacuolar (H )-ATPases

21 January 2018

1 reference

The V-type H -ATPase in vesicular trafficking: targeting, regulation and function

21 January 2018

1 reference

Electrophysiological analysis of the yeast V-type proton pump: variable coupling ratio and proton shunt.

21 January 2018

1 reference

Regulation and isoform function of the V-ATPases

21 January 2018

1 reference

Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase

21 January 2018

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V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

21 January 2018

1 reference

Regulation of vacuolar proton-translocating ATPase activity and assembly by extracellular pH

21 January 2018

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PKA regulates vacuolar H -ATPase localization and activity via direct phosphorylation of the a subunit in kidney cells

21 January 2018

1 reference

Regulation by salt of vacuolar H -ATPase and H -pyrophosphatase activities and Na /H exchange

21 January 2018

1 reference

Inhibitors of V-ATPases: old and new players

21 January 2018

1 reference

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

21 January 2018

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Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions

21 January 2018

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Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice

21 January 2018

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An H P-ATPase on the tonoplast determines vacuolar pH and flower colour

21 January 2018

1 reference

H -PPases: yesterday, today and tomorrow.

21 January 2018

1 reference

Emerging roles of alkali cation/proton exchangers in organellar homeostasis

21 January 2018

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Four Na /H exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation

21 January 2018

1 reference

Plant NHX cation/proton antiporters

21 January 2018

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Identification of three distinct phylogenetic groups of CAX cation/proton antiporters.

21 January 2018

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AtNHX3 is a vacuolar K /H antiporter required for low-potassium tolerance in Arabidopsis thaliana

21 January 2018

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Vacuolar cation/H antiporters of Saccharomyces cerevisiae

21 January 2018

1 reference

Rho, Rho-kinase, and the actin cytoskeleton regulate the Na -H exchanger in sea urchin eggs.

21 January 2018

1 reference

The sodium/proton exchanger NHE8 regulates late endosomal morphology and function

21 January 2018

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The Na /H exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion

21 January 2018

1 reference

The Arabidopsis intracellular Na /H antiporters NHX5 and NHX6 are endosome associated and necessary for plant growth and development

21 January 2018

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Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.

21 January 2018

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Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis

21 January 2018

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Lysosomal pathology and osteopetrosis upon loss of H -driven lysosomal Cl- accumulation

21 January 2018

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The mechanochemistry of V-ATPase proton pumps

21 January 2018

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The pH of the secretory pathway: measurement, determinants, and regulation

21 January 2018

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The Cl-/H antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

21 January 2018

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Unimpaired lysosomal acidification in respiratory epithelial cells in cystic fibrosis

21 January 2018

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Chloride channels of intracellular membranes

21 January 2018

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Presence of a vacuolar H -pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H -ATPase

21 January 2018

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A possible role for Na ,K -ATPase in regulating ATP-dependent endosome acidification

21 January 2018

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Role of endosomal Na -K -ATPase and cardiac steroids in the regulation of endocytosis

21 January 2018

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In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force

21 January 2018

1 reference

Characterization of two-pore channel 2 (TPCN2)-mediated Ca2 currents in isolated lysosomes

21 January 2018

1 reference

Existence of an adenosine 5'-triphosphate dependent proton translocase in bovine neurosecretory granule membrane

21 January 2018

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pH gradient across the lysosomal membrane generated by selective cation permeability and donnan equilibrium

21 January 2018

1 reference

Determinants of [Cl-] in recycling and late endosomes and Golgi complex measured using fluorescent ligands

21 January 2018

1 reference

64 The measurement of membrane potential and ΔpH in cells, organelles, and vesicles

21 January 2018

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NAADP induces pH changes in the lumen of acidic Ca2 stores

21 January 2018

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Cell surface levels of organellar Na /H exchanger isoform 6 are regulated by interaction with RACK1.

21 January 2018

1 reference

Pharmacological modulation of sarcoplasmic reticulum function in smooth muscle

21 January 2018

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Calcium in the Golgi apparatus

21 January 2018

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Unique characteristics of Ca2 homeostasis of the trans-Golgi compartment

21 January 2018

1 reference

21 January 2018

Vacuolar Ca(2 ) uptake.

1 reference

Calcium pumps in health and disease

21 January 2018

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ATP-driven Ca2 /H antiport in acid vesicles from Dictyostelium

21 January 2018

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Acidic calcium stores of Saccharomyces cerevisiae

21 January 2018

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Molecular cloning of an intracellular P-type ATPase from Dictyostelium that is up-regulated in calcium-adapted cells

21 January 2018

1 reference

Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

21 January 2018

1 reference

Functional characterization of thapsigargin and agonist-insensitive acidic Ca2 stores in Drosophila melanogaster S2 cell lines

21 January 2018

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Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2 signaling upon lysosome proliferation.

21 January 2018

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The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction

21 January 2018

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Organelle selection determines agonist-specific Ca2 signals in pancreatic acinar and beta cells

21 January 2018

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NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata

21 January 2018

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NAADP, cADPR and IP3 all release Ca2 from the endoplasmic reticulum and an acidic store in the secretory granule area.

21 January 2018

1 reference

Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.

21 January 2018

1 reference

Generation of cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate by CD38 for Ca2 signaling in interleukin-8-treated lymphokine-activated killer cells

21 January 2018

1 reference

Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1.

21 January 2018

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Intravesicular calcium release mediates the motion and exocytosis of secretory organelles: a study with adrenal chromaffin cells

21 January 2018

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Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

21 January 2018

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An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles

21 January 2018

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An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2 signals

21 January 2018

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Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure

21 January 2018

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NAADP mobilizes calcium from acidic organelles through two-pore channels

21 January 2018

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Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2 ) signaling and endolysosomal trafficking

21 January 2018

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Ca2 /H exchange in acidic vacuoles of Trypanosoma brucei

21 January 2018

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Ca(2 ) transport into an intracellular acidic compartment of Candida parapsilosis

21 January 2018

1 reference

A dynamic pool of calcium in catecholamine storage vesicles. Exploration in living cells by a novel vesicle-targeted chromogranin A-aequorin chimeric photoprotein

21 January 2018

1 reference

Na /Ca2 exchangers: three mammalian gene families control Ca2 transport.

21 January 2018

1 reference

A functional genomic and proteomic perspective of sea urchin calcium signaling and egg activation

21 January 2018

1 reference

Na /Ca2 -K exchangers (NCKX): functional properties and physiological roles

21 January 2018

1 reference

The co-presence of Na /Ca2 -K exchanger and Na /Ca2 exchanger in bovine adrenal chromaffin cells.

21 January 2018

1 reference

SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

21 January 2018

1 reference

Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2 from a thapsigargin-insensitive pool

21 January 2018

1 reference

The two-pore channel TPCN2 mediates NAADP-dependent Ca(2 )-release from lysosomal stores

21 January 2018

1 reference

Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2 release from insulin-containing vesicles in living pancreatic beta-cells (MIN6).

21 January 2018

1 reference

Dense core secretory vesicles revealed as a dynamic Ca(2 ) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.

21 January 2018

1 reference

The lysosomal Ca2 pool in MDCK cells can be released by ins(1,4,5)P3-dependent hormones or thapsigargin but does not activate store-operated Ca2 entry.

21 January 2018

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65Zn2 Transport by lobster hepatopancreatic lysosomal membrane vesicles

21 January 2018

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The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2 store, with functional properties distinct from those of the endoplasmic reticulum

21 January 2018

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Endocytic vesicles contain a calmodulin-activated Ca2 pump that mediates the inhibition of acidification by calcium

21 January 2018

1 reference

Characterization of the P‐Type and V‐Type ATPases of Cholinergic Synaptic Vesicles and Coupling of Nucleotide Hydrolysis to Acetylcholine Transport

21 January 2018

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Subcellular distribution of Ca2 pumping sites in human neutrophils

21 January 2018

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Ca2 accumulation into acidic organelles mediated by Ca2 - and vacuolar H -ATPases in human platelets

21 January 2018

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Two distinct Ca2 compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets

21 January 2018

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Intracellular calcium release from human platelets: different messengers for multiple stores

21 January 2018

1 reference

Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone

21 January 2018

1 reference

STIM1 and STIM2 are located in the acidic Ca2 stores and associates with Orai1 upon depletion of the acidic stores in human platelets

21 January 2018

1 reference

Phenotypes of SERCA and PMCA knockout mice

21 January 2018

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Two distinct calcium pools in the endoplasmic reticulum of HEK-293T cells.

21 January 2018

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Structural basis of ion pumping by Ca2 -ATPase of the sarcoplasmic reticulum

21 January 2018

1 reference

Cytosolic calcium homeostasis in fungi: roles of plasma membrane transport and intracellular sequestration of calcium

21 January 2018

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NAADP mobilizes calcium from the endoplasmic reticular Ca(2 ) store in T-lymphocytes

21 January 2018

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Calcium uptake via endocytosis with rapid release from acidifying endosomes.

21 January 2018

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Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells

21 January 2018

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Dynamic ca(2 )changes in neutrophil phagosomes A source for intracellular ca(2 )during phagolysosome formation?

21 January 2018

1 reference

Calreticulin, a Ca2 -binding chaperone of the endoplasmic reticulum

21 January 2018

1 reference

Ca2 signaling and calcium binding chaperones of the endoplasmic reticulum

21 January 2018

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Modulation of ryanodine receptor by luminal calcium and accessory proteins in health and cardiac disease

21 January 2018

1 reference

Calcium binding capacity of the cytosol and endoplasmic reticulum of mouse pancreatic acinar cells.

21 January 2018

1 reference

Acidocalcisomes - conserved from bacteria to man.

21 January 2018

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Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes.

21 January 2018

1 reference

Melanin has a role in Ca2 homeostasis in human melanocytes.

21 January 2018

1 reference

Calmodulin activates NAD kinase of sea urchin eggs: An early event of fertilization

21 January 2018

1 reference

A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose

21 January 2018

1 reference

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.

21 January 2018

1 reference

Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

21 January 2018

1 reference

Ca(2 )-induced Ca2 release in sea urchin egg homogenates: modulation by cyclic ADP-ribose

21 January 2018

1 reference

Pharmacological properties of the Ca2 -release mechanism sensitive to NAADP in the sea urchin egg

21 January 2018

1 reference

NAADP induces Ca2 oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2 stores

21 January 2018

1 reference

NAADP, a new intracellular messenger that mobilizes Ca2 from acidic stores

21 January 2018

1 reference

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling

21 January 2018

1 reference

Coordination of agonist-induced Ca2 -signalling patterns by NAADP in pancreatic acinar cells

21 January 2018

1 reference

Nicotinate-adenine dinucleotide phosphate-induced Ca(2 )-release does not behave as a Ca(2 )-induced Ca(2 )-release system

21 January 2018

1 reference

Nicotinic acid adenine dinucleotide phosphate triggers Ca2 release from brain microsomes

21 January 2018

1 reference

Spatial control of Ca2 signaling by nicotinic acid adenine dinucleotide phosphate diffusion and gradients

21 January 2018

1 reference

Coordination of Ca2 signalling by NAADP.

21 January 2018

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Ca(2 ) transfer from the ER to mitochondria: when, how and why

21 January 2018

1 reference

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

1 reference

Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle.

21 January 2018

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Ca(2 ) signaling occurs via second messenger release from intraorganelle synthesis sites

21 January 2018

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Fertilization and nicotinic acid adenine dinucleotide phosphate induce pH changes in acidic Ca(2 ) stores in sea urchin eggs

21 January 2018

1 reference

The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2 mobilization from lysosomes in pancreatic acinar cells

21 January 2018

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Lysosome and lysosome-related organelles responsible for specialized functions in higher organisms, with special emphasis on vacuolar-type proton ATPase

21 January 2018

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Functional ryanodine receptor expression is required for NAADP-mediated local Ca2 signaling in T-lymphocytes.

21 January 2018

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Effect of nicotinic acid adenine dinucleotide phosphate on ryanodine calcium release channel in heart

21 January 2018

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Nicotinic acid-adenine dinucleotide phosphate activates the skeletal muscle ryanodine receptor

21 January 2018

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Lack of effect of cADP-ribose and NAADP on the activity of skeletal muscle and heart ryanodine receptors

21 January 2018

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TPC2 is a novel NAADP-sensitive Ca2 release channel, operating as a dual sensor of luminal pH and Ca2

21 January 2018

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Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.

21 January 2018

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21 January 2018

Mucolipidosis type IV.

1 reference

Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

21 January 2018

1 reference

Mucolipins: Intracellular TRPML1-3 channels

21 January 2018

1 reference

Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic

21 January 2018

1 reference

Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes

21 January 2018

1 reference

Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway

21 January 2018

1 reference

Cation channel activity of mucolipin-1: the effect of calcium.

21 January 2018

1 reference

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

21 January 2018

1 reference

Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2 release channel from liver lysosomes of rats

21 January 2018

1 reference

TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2 release channel in coronary arterial myocytes

21 January 2018

1 reference

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels

21 January 2018

1 reference

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2 release channels in the endolysosome

21 January 2018

1 reference

TRPM2: a multifunctional ion channel for calcium signalling.

21 January 2018

1 reference

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

21 January 2018

1 reference

TRPM2 functions as a lysosomal Ca2 -release channel in beta cells

21 January 2018

1 reference

Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.

21 January 2018

1 reference

Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis

21 January 2018

1 reference

TPCs: Endolysosomal channels for Ca2 mobilization from acidic organelles triggered by NAADP

21 January 2018

1 reference

Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals

21 January 2018

1 reference

Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels

21 January 2018

1 reference

A putative two pore channel AtTPC1 mediates Ca(2 ) flux in Arabidopsis leaf cells

21 January 2018

1 reference

Identification of putative voltage-dependent Ca2 -permeable channels involved in cryptogein-induced Ca2 transients and defense responses in tobacco BY-2 cells.

21 January 2018

1 reference

The vacuolar Ca2 -activated channel TPC1 regulates germination and stomatal movement

21 January 2018

1 reference

The fou2 mutation in the major vacuolar cation channel TPC1 confers tolerance to inhibitory luminal calcium

21 January 2018

1 reference

TPC1-SV channels gain shape

21 January 2018

1 reference

Calcium release from the endoplasmic reticulum of higher plants elicited by the NADP metabolite nicotinic acid adenine dinucleotide phosphate

21 January 2018

1 reference

Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

21 January 2018

1 reference

Planar patch clamp approach to characterize ionic currents from intact lysosomes

21 January 2018

1 reference

Identification of a chemical probe for NAADP by virtual screening

21 January 2018

1 reference

A functional role for nicotinic acid adenine dinucleotide phosphate in oxytocin-mediated contraction of uterine smooth muscle from rat.

21 January 2018

1 reference

Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2 spiking in mouse pancreatic acinar cells

21 January 2018

1 reference

Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2 signal that is essential for insulin secretion in mouse pancreatic islets

21 January 2018

1 reference

CD38-mediated Ca2 signaling contributes to angiotensin II-induced activation of hepatic stellate cells: attenuation of hepatic fibrosis by CD38 ablation

21 January 2018

1 reference

Transformation of local Ca2 spikes to global Ca2 transients: the combinatorial roles of multiple Ca2 releasing messengers

21 January 2018

1 reference

Aberrant Ca2 signalling through acidic calcium stores in pancreatic acinar cells

21 January 2018

1 reference

NAADP triggers the fertilization potential in starfish oocytes

21 January 2018

1 reference

Sperm deliver a new second messenger: NAADP

21 January 2018

1 reference

Pharmacological characterization of NAADP-induced Ca2 signals in starfish oocytes

21 January 2018

1 reference

The role of intraorganellar Ca(2 ) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles

21 January 2018

1 reference

CUPpling calcium to lysosomal biogenesis.

21 January 2018

1 reference

Lysosomes: fusion and function

21 January 2018

1 reference

TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle

21 January 2018

1 reference

NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cells

21 January 2018

1 reference

Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels

21 January 2018

1 reference

Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation

21 January 2018

1 reference

Two newly identified genetic determinants of pigmentation in Europeans

21 January 2018

1 reference

Prevalence of lysosomal storage disorders

21 January 2018

1 reference

The epidemiology of progressive intellectual and neurological deterioration in childhood

21 January 2018

1 reference

Niemann-Pick disease type C.

21 January 2018

1 reference

Correction: Uncoupling of Longevity and Telomere Length in C. elegans

21 January 2018

1 reference

Lipids on trial: the search for the offending metabolite in Niemann-Pick type C disease

21 January 2018

1 reference

Cellular pathology of Niemann-Pick type C disease

21 January 2018

1 reference

Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking

21 January 2018

1 reference

Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells

21 January 2018

1 reference

The structure and function of the Niemann-Pick C1 protein

21 January 2018

1 reference

Transmembrane molecular pump activity of Niemann-Pick C1 protein

21 January 2018

1 reference

Multidrug permeases and subcellular cholesterol transport

21 January 2018

1 reference

Identification of the gene causing mucolipidosis type IV.

21 January 2018

1 reference

TRPMLs: in sickness and in health

21 January 2018

1 reference

The neurogenetics of mucolipidosis type IV

21 January 2018

1 reference

Cultured Skin Fibroblasts Derived from Patients with Mucolipidosis 4 Are Auto-Fluorescent

21 January 2018

1 reference

Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease

21 January 2018

1 reference

The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans

21 January 2018

1 reference

Mucolipin 1: endocytosis and cation channel--a review

21 January 2018

1 reference

TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity

21 January 2018

1 reference

Mucolipidosis type IV: the effect of increased lysosomal pH on the abnormal lysosomal storage.

21 January 2018

1 reference

Functional links between mucolipin-1 and Ca2 -dependent membrane trafficking in mucolipidosis IV

21 January 2018

1 reference

Molecular pathophysiology of mucolipidosis type IV: pH dysregulation of the mucolipin-1 cation channel.

21 January 2018

1 reference

Identification of the penta-EF-hand protein ALG-2 as a Ca2 -dependent interactor of mucolipin-1.

21 January 2018

1 reference

Mucolipin-3 Regulates Luminal Calcium, Acidification, and Membrane Fusion in the Endosomal Pathway

21 January 2018

1 reference

Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2 -ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin

21 January 2018

1 reference

Regulation of phagosomal acidification. Differential targeting of Na /H exchangers, Na /K -ATPases, and vacuolar-type H -atpases

21 January 2018

1 reference

Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins

21 January 2018

1 reference

pH of TGN and recycling endosomes of H /K -ATPase-transfected HEK-293 cells: implications for pH regulation in the secretory pathway

21 January 2018

1 reference

Direct measurement of trans-Golgi pH in living cells and regulation by second messengers

21 January 2018

1 reference

The granular chloride channel ClC-3 is permissive for insulin secretion

21 January 2018

1 reference

Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.

21 January 2018

1 reference

An expanded biological repertoire for Ins(3,4,5,6)P4 through its modulation of ClC-3 function

21 January 2018

1 reference

ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation

21 January 2018

1 reference

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

21 January 2018

1 reference

ClC-3—A Granular Anion Transporter Involved in Insulin Secretion?

21 January 2018

1 reference

Ca2 and electrolyte mobilization following agonist application to the pancreatic beta cell line HIT.

21 January 2018

1 reference

Lysosomal composition in cultured vascular smooth muscle cells: electron probe analysis

21 January 2018

1 reference

Calcium containing lysosomes in the normal chick duodenum: A histochemical and analytical electron microscopic study

21 January 2018

1 reference

Elemental analysis of the Mycobacterium avium phagosome in Balb/c mouse macrophages.

21 January 2018

1 reference

Calcium dynamics in bovine adrenal medulla chromaffin cell secretory granules

21 January 2018

1 reference

Free concentrations of sodium, potassium and calcium in chromaffin granules

21 January 2018

1 reference

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

21 January 2018

1 reference

Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-Golgi pH.

21 January 2018

1 reference

The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity

21 January 2018

1 reference

Simultaneous intracellular chloride and pH measurements using a GFP-based sensor

21 January 2018

1 reference

Regulated proteolysis by cortical granule serine protease 1 at fertilization

21 January 2018

1 reference

Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells.

21 January 2018

1 reference

Genetically encoded FRET sensors to monitor intracellular Zn2 homeostasis

21 January 2018

1 reference

Potassium homeostasis in vacuolate plant cells

21 January 2018

1 reference

Electrical measurements on endomembranes

21 January 2018

1 reference

Contributions of Intracellular Compartments to Calcium Dynamics: Implicating an Acidic Store

21 January 2018

1 reference

Role of Ca2 /K ion exchange in intracellular storage and release of Ca2

21 January 2018

1 reference

Inositol 1,4,5-trisphosphate microinjection activates sea urchin eggs

21 January 2018

1 reference

Purification and reconstitution of the calcium release channel from skeletal muscle

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1042/BJ20110949

1 reference

25 August 2017

1 reference