The P-glycoprotein multidrug transporter. (Q37941756)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

review article

1 reference

title

The P-glycoprotein multidrug transporter (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Frances J Sharom

series ordinal

1

1 reference

25 August 2017

publication date

1 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

published in

Essays in Biochemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

161-178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21967057 AND SRC:MED&resulttype=core&format=json

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

13 February 2020

cites work

1 reference

Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen

21 January 2018

1 reference

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

P-Glycoprotein, a gatekeeper in the blood-brain barrier

21 January 2018

1 reference

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

ABC efflux pump-based resistance to chemotherapy drugs.

21 January 2018

1 reference

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

1 reference

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

21 January 2018

1 reference

Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein).

21 January 2018

1 reference

The bile salt export pump

21 January 2018

1 reference

Multidrug resistance reversal agents

21 January 2018

1 reference

Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism

21 January 2018

1 reference

Reversal of multidrug resistance by surfactants

21 January 2018

1 reference

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs

21 January 2018

1 reference

Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state

21 January 2018

1 reference

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

21 January 2018

1 reference

Structure of a bacterial multidrug ABC transporter

21 January 2018

1 reference

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

Do drug substrates enter the common drug-binding pocket of P-glycoprotein through "gates"?

21 January 2018

1 reference

Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

21 January 2018

1 reference

Positively Cooperative Sites for Drug Transport by P‐Glycoprotein with Distinct Drug Specificities

21 January 2018

1 reference

Is the multidrug transporter a flippase?

21 January 2018

1 reference

P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors

21 January 2018

1 reference

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

1 reference

The motor domains of ABC-transporters. What can structures tell us?

21 January 2018

1 reference

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

1 reference

Subunit interactions in ABC transporters: towards a functional architecture

21 January 2018

1 reference

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

21 January 2018

1 reference

The translocation mechanism of P-glycoprotein.

21 January 2018

1 reference

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

21 January 2018

1 reference

The catalytic cycle of P-glycoprotein

21 January 2018

1 reference

The occluded nucleotide conformation of p-glycoprotein

21 January 2018

1 reference

Characterization of an asymmetric occluded state of P-glycoprotein with two bound nucleotides: implications for catalysis

21 January 2018

1 reference

Catalytic cycle of ATP hydrolysis by P-glycoprotein: evidence for formation of the E.S reaction intermediate with ATP-gamma-S, a nonhydrolyzable analogue of ATP.

21 January 2018

1 reference

The ATP switch model for ABC transporters

21 January 2018

1 reference

The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p.

21 January 2018

1 reference

ABC multidrug transporters: structure, function and role in chemoresistance.

21 January 2018

1 reference

Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics

21 January 2018

1 reference

Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations

21 January 2018

1 reference

Membrane transporters in drug development

21 January 2018

1 reference

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters

21 January 2018

1 reference

ABC transporters in the balance: is there a role in multidrug resistance?

21 January 2018

1 reference

ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?

21 January 2018

1 reference

Targeting multidrug resistance in cancer

21 January 2018

1 reference