Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death (Q37941527)

25 August 2017

1 reference

title

Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death (English)

1 reference

25 August 2017

Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death (English)

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

13 December 2024

0 references

1

Jaume Folch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21965004

13 December 2024

2

Felix Junyent

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21965004

13 December 2024

7

Mercè Pallàs

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21965004

13 December 2024

8

Antoni Camins

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21965004

13 December 2024

author name string

Ester Verdaguer

3

1 reference

25 August 2017

Carme Auladell

4

1 reference

25 August 2017

Carlos Beas-Zarate

6

1 reference

25 August 2017

Javier G. Pizarro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21965004

13 December 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21965004

13 December 2024

publication date

1 October 2011

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full work available at URL

25 August 2017

http://link.springer.com/content/pdf/10.1007/s12640-011-9277-4.pdf

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

http://link.springer.com/article/10.1007/s12640-011-9277-4/fulltext.html

13 December 2024

file format

HyperText Markup Language

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

http://link.springer.com/content/pdf/10.1007/s12640-011-9277-4

13 December 2024

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

13 December 2024

published in

Neurotoxicity Research

1 reference

25 August 2017

volume

22

1 reference

25 August 2017

issue

3

1 reference

25 August 2017

page(s)

195-207

1 reference

p27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: a proof-of-concept study

25 August 2017

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Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

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Review: cell cycle aberrations and neurodegeneration

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Replicating Huntington's disease phenotype in experimental animals

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3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

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Inhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis

21 January 2018

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Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease

21 January 2018

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Role of the cell cycle in the pathobiology of central nervous system trauma

21 January 2018

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Employing new cellular therapeutic targets for Alzheimer's disease: a change for the better?

21 January 2018

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Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

21 January 2018

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The nature of the cell cycle in neurons: focus on a "non-canonical" pathway of DNA replication causally related to death.

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The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.

21 January 2018

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Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter

21 January 2018

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Cdk5 deregulation in the pathogenesis of Alzheimer's disease

21 January 2018

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Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

21 January 2018

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Mitochondria in Huntington's disease

21 January 2018

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Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

21 January 2018

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The E2F transcriptional network: old acquaintances with new faces

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.

21 January 2018

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Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease.

21 January 2018

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Apaf-1 is a mediator of E2F-1-induced apoptosis

21 January 2018

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E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Divide and die: cell cycle events as triggers of nerve cell death.

21 January 2018

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Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The transcription factor E2F1 promotes dopamine-evoked neuronal apoptosis by a mechanism independent of transcriptional activation

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cdk5: Links to DNA damage

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The RB-E2F1 pathway regulates autophagy.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Induction of cell-cycle regulators in simian immunodeficiency virus encephalitis

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Altered subcellular distribution of transcriptional regulators in response to Abeta peptide and during Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Expression patterns of retinoblastoma protein in Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

21 January 2018

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6-Hydroxydopamine-induced PC12 cell death is mediated by MEF2D down-regulation.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Oxidative stress, cell cycle, and neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The harlequin mouse mutation downregulates apoptosis-inducing factor

21 January 2018

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NF-kappaB is involved in the survival of cerebellar granule neurons: association of IkappaBbeta [correction of Ikappabeta] phosphorylation with cell survival

21 January 2018

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Cell cycle activation linked to neuronal cell death initiated by DNA damage

21 January 2018

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Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

21 January 2018

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Cyclin D1 immunoreactivity changes in CA1 pyramidal neurons and dentate granule cells in the gerbil hippocampus after transient forebrain ischemia

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Apoptosis, autophagy, and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cdk5: multitasking between physiological and pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Neuronal expression of cell cycle-related proteins after brain ischaemia in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Absence of the transcription factor E2F1 attenuates brain injury and improves behavior after focal ischemia in mice

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

G1 cell-cycle control and cancer

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

To die or not to die: DNA repair in neurons

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Genetic determinants at the interface of cancer and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Up-regulation of E2F-1 in Down's syndrome brain exhibiting neuropathological features of Alzheimer-type dementia

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The cell division cycle and the pathophysiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

The cell cycle as a therapeutic target for Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cyclin-dependent kinases as a therapeutic target for stroke.

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Acetylation status of E2F-1 has an important role in the regulation of E2F-1-mediated transactivation of tumor suppressor p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Flavopiridol: an antitumor drug with potential application in the treatment of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Effects of MPP on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F - at the crossroads of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

p53 and E2f: partners in life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F1 regulates autophagy and the transcription of autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cell cycle machinery and stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIP(short).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Constitutive expression of functionally active cyclin-dependent kinases and their binding partners suggests noncanonical functions of cell cycle regulators in differentiated neurons

21 January 2018

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A putative role for cell cycle-related proteins in microtubule-based neuroplasticity

21 January 2018

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https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cell cycle activation in postmitotic neurons is essential for DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F1-induced apoptosis: turning killers into therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

E2F1 induces cell death, calpain activation, and MDMX degradation in a transcription independent manner implicating a novel role for E2F1 in neuronal loss in SIV encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cdk5, a therapeutic target for Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

The expression of cell cycle proteins in neurons and its relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Mitotic mechanisms in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

The cell cycle in Alzheimer disease: a unique target for neuropharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Alzheimer's disease: the two-hit hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Alzheimer disease, the two-hit hypothesis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S12640-011-9277-4

DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells.

21 January 2018

1 reference

12 December 2020

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

12 December 2020

p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death

1 reference

12 December 2020

Pin1 inhibition activates cyclin D and produces neurodegenerative pathology

1 reference

12 December 2020

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease

1 reference

12 December 2020

Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease

1 reference

12 December 2020

Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease

1 reference

12 December 2020

Erratic expression of DNA polymerases by beta-amyloid causes neuronal death.

1 reference

12 December 2020

The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons.

1 reference

12 December 2020

Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis

1 reference

12 December 2020

Cyclin-dependent kinases in neural development and degeneration

1 reference

12 December 2020

Multiple Pathways of Neuronal Death Induced by DNA-Damaging Agents, NGF Deprivation, and Oxidative Stress

1 reference

12 December 2020

Why do neurons enter the cell cycle?

1 reference

12 December 2020

Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats

1 reference

12 December 2020

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

12 December 2020

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

12 December 2020

Cdk5: Mediator of neuronal development, death and the response to DNA damage

1 reference

12 December 2020

Emerging pathogenic role for cyclin dependent kinases in neurodegeneration

1 reference

12 December 2020

Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

1 reference

12 December 2020

The transcription factor E2F1 modulates apoptosis of neurons

1 reference

12 December 2020

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

1 reference

12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

12 December 2020

Increased DeltaN-p73 expression in tumors by upregulation of the E2F1-regulated, TA-promoter-derived DeltaN'-p73 transcript

1 reference

12 December 2020

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

12 December 2020

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

12 December 2020

Identifiers

1 reference

25 August 2017

1 reference