PI3K: a potential therapeutic target for cancer (Q37936950)

25 August 2017

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title

PI3K: a potential therapeutic target for cancer (English)

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25 August 2017

Yingwei Chen

1

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25 August 2017

Bao-Can Wang

series ordinal

2

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25 August 2017

Yongtao Xiao

series ordinal

3

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25 August 2017

publication date

1 July 2012

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Journal of Cellular Physiology

25 August 2017

published in

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25 August 2017

volume

227

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25 August 2017

issue

7

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25 August 2017

page(s)

2818-2821

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

25 August 2017

cites work

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The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

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The regulation and function of Class III PI3Ks: novel roles for Vps34.

21 January 2018

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Autophagy signaling and the cogwheels of cancer

21 January 2018

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New phosphatidylinositol 3-kinase inhibitors for cancer

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

21 January 2018

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p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways

21 January 2018

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PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.

21 January 2018

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The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

21 January 2018

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 January 2018

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

21 January 2018

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CD151 amplifies signaling by integrin α6β1 to PI3K and induces the epithelial-mesenchymal transition in HCC cells

21 January 2018

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Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis

21 January 2018

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The role of autophagy in cancer development and response to therapy.

21 January 2018

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PI3Kγ mediates kaposi's sarcoma-associated herpesvirus vGPCR-induced sarcomagenesis.

21 January 2018

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Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

21 January 2018

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Phosphoinositide signaling and the regulation of membrane trafficking in yeast

21 January 2018

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Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase

21 January 2018

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

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EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

21 January 2018

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

21 January 2018

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Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol

21 January 2018

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Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

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Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 January 2018

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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

21 January 2018

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Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

21 January 2018

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Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

21 January 2018

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Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

21 January 2018

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Lovastatin Inhibits VEGFR and AKT Activation: Synergistic Cytotoxicity in Combination with VEGFR Inhibitors

21 January 2018

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Vimentin is a novel AKT1 target mediating motility and invasion

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.23038

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25 August 2017

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