Biogenesis of spliceosomal small nuclear ribonucleoproteins (Q37913270)

25 August 2017

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title

Biogenesis of spliceosomal small nuclear ribonucleoproteins (English)

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ribonucleoprotein complex

25 August 2017

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Utz Fischer

1

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author name string

Clemens Englbrecht

series ordinal

2

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25 August 2017

Ashwin Chari

series ordinal

3

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25 August 2017

publication date

25 April 2011

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Wiley interdisciplinary reviews. RNA

25 August 2017

published in

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25 August 2017

volume

2

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25 August 2017

issue

5

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25 August 2017

page(s)

718-731

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Pre-mRNA splicing: awash in a sea of proteins

25 August 2017

cites work

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The spliceosome: design principles of a dynamic RNP machine

21 January 2018

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Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure

21 January 2018

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Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

21 January 2018

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A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro

21 January 2018

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Identification of both shared and distinct proteins in the major and minor spliceosomes

21 January 2018

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Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns

21 January 2018

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snRNAs contain specific SMN-binding domains that are essential for snRNP assembly

21 January 2018

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Comparison of the RNA polymerase III transcription machinery in Schizosaccharomyces pombe, Saccharomyces cerevisiae and human

21 January 2018

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Small nuclear RNA genes: a model system to study fundamental mechanisms of transcription

21 January 2018

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Expression of human snRNA genes from beginning to end.

21 January 2018

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Crossing the line between RNA polymerases: transcription of human snRNA genes by RNA polymerases II and III.

21 January 2018

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Eukaryotic transcription factor-DNA complexes.

21 January 2018

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

21 January 2018

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SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III

21 January 2018

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TBP, a universal eukaryotic transcription factor?

21 January 2018

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Cloning, expression, and function of TFC5, the gene encoding the B" component of the Saccharomyces cerevisiae RNA polymerase III transcription factor TFIIIB.

21 January 2018

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Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme

21 January 2018

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Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II

21 January 2018

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The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain

21 January 2018

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Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression

21 January 2018

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Assembly and intracellular transport of snRNP particles

21 January 2018

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Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

21 January 2018

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m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain

21 January 2018

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Monomethylated cap structures facilitate RNA export from the nucleus

21 January 2018

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A cap-binding protein complex mediating U snRNA export

21 January 2018

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PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation

21 January 2018

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Exporting RNA from the nucleus to the cytoplasm

21 January 2018

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RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase

21 January 2018

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Cajal body surveillance of U snRNA export complex assembly

21 January 2018

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Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts

21 January 2018

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Coiled bodies preferentially associate with U4, U11, and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes

21 January 2018

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RNA-mediated interaction of Cajal bodies and U2 snRNA genes.

21 January 2018

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The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

21 January 2018

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The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

21 January 2018

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A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs

21 January 2018

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Essential role for the SMN complex in the specificity of snRNP assembly

21 January 2018

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Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

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Correlation between severity and SMN protein level in spinal muscular atrophy

21 January 2018

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Cellular strategies for the assembly of molecular machines

21 January 2018

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Deciphering the assembly pathway of Sm-class U snRNPs

21 January 2018

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Chaperoning ribonucleoprotein biogenesis in health and disease

21 January 2018

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Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln

21 January 2018

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The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins

21 January 2018

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Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

21 January 2018

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Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

21 January 2018

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An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

21 January 2018

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pICln inhibits snRNP biogenesis by binding core spliceosomal proteins

21 January 2018

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Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis

21 January 2018

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The Gemin5 protein of the SMN complex identifies snRNAs

21 January 2018

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Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus

21 January 2018

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RNA-quality control by the exosome

21 January 2018

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Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.

21 January 2018

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Assembly and localization of the U1-specific snRNP C protein in the amphibian oocyte

21 January 2018

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The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal

21 January 2018

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Nuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytes

21 January 2018

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Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport

21 January 2018

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Nuclear import of U snRNPs requires importin beta

21 January 2018

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Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure

21 January 2018

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The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro

21 January 2018

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Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1

21 January 2018

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Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus

21 January 2018

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The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway

21 January 2018

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Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein

21 January 2018

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SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta

21 January 2018

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The U1 small nuclear ribonucleoprotein (snRNP) 70K protein is transported independently of U1 snRNP particles via a nuclear localization signal in the RNA-binding domain

21 January 2018

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An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins

21 January 2018

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Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

21 January 2018

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Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies.

21 January 2018

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Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway

21 January 2018

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WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies

21 January 2018

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Targeting SMN to Cajal bodies and nuclear gems during neuritogenesis.

21 January 2018

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Pumping RNA: nuclear bodybuilding along the RNP pipeline.

21 January 2018

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Dynamic control of Cajal body number during zebrafish embryogenesis

21 January 2018

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A small nucleolar guide RNA functions both in 2'-O-ribose methylation and pseudouridylation of the U5 spliceosomal RNA

21 January 2018

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A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles

21 January 2018

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A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

21 January 2018

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Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing

21 January 2018

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Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

21 January 2018

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Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.

21 January 2018

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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

21 January 2018

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Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies

21 January 2018

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RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies

21 January 2018

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Detection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transfer

21 January 2018

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A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

21 January 2018

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A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formation

21 January 2018

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Enhancement of U4/U6 small nuclear ribonucleoprotein particle association in Cajal bodies predicted by mathematical modeling

21 January 2018

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Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies

21 January 2018

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A role for Cajal bodies in the final steps of U2 snRNP biogenesis

21 January 2018

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Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

21 January 2018

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Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death

21 January 2018

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Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy

21 January 2018

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SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing

21 January 2018

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Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs

21 January 2018

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The neurobiology of childhood spinal muscular atrophy.

21 January 2018

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The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy

21 January 2018

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Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

21 January 2018

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Impaired minor tri-snRNP assembly generates differential splicing defects of U12-type introns in lymphoblasts derived from a type I SMA patient

21 January 2018

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Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

21 January 2018

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Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7.

21 January 2018

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Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster

21 January 2018

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SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WRNA.87

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release_poo46akwrfdplbnq4dmkbpubuu

25 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/poo46akwrfdplbnq4dmkbpubuu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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